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Journal Abstract Search

425 related items for PubMed ID: 24275666

  • 21. REDD1 enhances protein phosphatase 2A-mediated dephosphorylation of Akt to repress mTORC1 signaling.
    Dennis MD, Coleman CS, Berg A, Jefferson LS, Kimball SR.
    Sci Signal; 2014 Jul 22; 7(335):ra68. PubMed ID: 25056877
    [Abstract] [Full Text] [Related]

  • 22. Livers with constitutive mTORC1 activity resist steatosis independent of feedback suppression of Akt.
    Kenerson HL, Subramanian S, McIntyre R, Kazami M, Yeung RS.
    PLoS One; 2015 Jul 22; 10(2):e0117000. PubMed ID: 25646773
    [Abstract] [Full Text] [Related]

  • 23. Sustained activation of mTORC1 in macrophages increases AMPKα-dependent autophagy to maintain cellular homeostasis.
    Pan H, Zhong XP, Lee S.
    BMC Biochem; 2016 Jul 07; 17(1):14. PubMed ID: 27387347
    [Abstract] [Full Text] [Related]

  • 24. Regulated in DNA damage and development 1 (REDD1) promotes cell survival during serum deprivation by sustaining repression of signaling through the mechanistic target of rapamycin in complex 1 (mTORC1).
    Dennis MD, McGhee NK, Jefferson LS, Kimball SR.
    Cell Signal; 2013 Dec 07; 25(12):2709-16. PubMed ID: 24018049
    [Abstract] [Full Text] [Related]

  • 25. NFκB up-regulation of glucose transporter 3 is essential for hyperactive mammalian target of rapamycin-induced aerobic glycolysis and tumor growth.
    Zha X, Hu Z, Ji S, Jin F, Jiang K, Li C, Zhao P, Tu Z, Chen X, Di L, Zhou H, Zhang H.
    Cancer Lett; 2015 Apr 01; 359(1):97-106. PubMed ID: 25578782
    [Abstract] [Full Text] [Related]

  • 26. Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1.
    Di Nardo A, Wertz MH, Kwiatkowski E, Tsai PT, Leech JD, Greene-Colozzi E, Goto J, Dilsiz P, Talos DM, Clish CB, Kwiatkowski DJ, Sahin M.
    Hum Mol Genet; 2014 Jul 15; 23(14):3865-74. PubMed ID: 24599401
    [Abstract] [Full Text] [Related]

  • 27. ERK and Akt signaling pathways function through parallel mechanisms to promote mTORC1 signaling.
    Winter JN, Jefferson LS, Kimball SR.
    Am J Physiol Cell Physiol; 2011 May 15; 300(5):C1172-80. PubMed ID: 21289294
    [Abstract] [Full Text] [Related]

  • 28. Differential contribution of insulin and amino acids to the mTORC1-autophagy pathway in the liver and muscle.
    Naito T, Kuma A, Mizushima N.
    J Biol Chem; 2013 Jul 19; 288(29):21074-21081. PubMed ID: 23744068
    [Abstract] [Full Text] [Related]

  • 29. Estradiol promotes pentose phosphate pathway addiction and cell survival via reactivation of Akt in mTORC1 hyperactive cells.
    Sun Y, Gu X, Zhang E, Park MA, Pereira AM, Wang S, Morrison T, Li C, Blenis J, Gerbaudo VH, Henske EP, Yu JJ.
    Cell Death Dis; 2014 May 15; 5(5):e1231. PubMed ID: 24832603
    [Abstract] [Full Text] [Related]

  • 30. The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of mTORC1.
    Kathage B, Gehlert S, Ulbricht A, Lüdecke L, Tapia VE, Orfanos Z, Wenzel D, Bloch W, Volkmer R, Fleischmann BK, Fürst DO, Höhfeld J.
    Biochim Biophys Acta Mol Cell Res; 2017 Jan 15; 1864(1):62-75. PubMed ID: 27756573
    [Abstract] [Full Text] [Related]

  • 31. Tuberous sclerosis complex inactivation disrupts melanogenesis via mTORC1 activation.
    Cao J, Tyburczy ME, Moss J, Darling TN, Widlund HR, Kwiatkowski DJ.
    J Clin Invest; 2017 Jan 03; 127(1):349-364. PubMed ID: 27918305
    [Abstract] [Full Text] [Related]

  • 32. Tuberous sclerosis complex 1: an epithelial tumor suppressor essential to prevent spontaneous prostate cancer in aged mice.
    Kladney RD, Cardiff RD, Kwiatkowski DJ, Chiang GG, Weber JD, Arbeit JM, Lu ZH.
    Cancer Res; 2010 Nov 01; 70(21):8937-47. PubMed ID: 20940396
    [Abstract] [Full Text] [Related]

  • 33. Piperlongumine promotes autophagy via inhibition of Akt/mTOR signalling and mediates cancer cell death.
    Makhov P, Golovine K, Teper E, Kutikov A, Mehrazin R, Corcoran A, Tulin A, Uzzo RG, Kolenko VM.
    Br J Cancer; 2014 Feb 18; 110(4):899-907. PubMed ID: 24434432
    [Abstract] [Full Text] [Related]

  • 34. Aberrant hyperactivation of akt and Mammalian target of rapamycin complex 1 signaling in sporadic chordomas.
    Han S, Polizzano C, Nielsen GP, Hornicek FJ, Rosenberg AE, Ramesh V.
    Clin Cancer Res; 2009 Mar 15; 15(6):1940-6. PubMed ID: 19276265
    [Abstract] [Full Text] [Related]

  • 35. Tumorigenesis in tuberous sclerosis complex is autophagy and p62/sequestosome 1 (SQSTM1)-dependent.
    Parkhitko A, Myachina F, Morrison TA, Hindi KM, Auricchio N, Karbowniczek M, Wu JJ, Finkel T, Kwiatkowski DJ, Yu JJ, Henske EP.
    Proc Natl Acad Sci U S A; 2011 Jul 26; 108(30):12455-60. PubMed ID: 21746920
    [Abstract] [Full Text] [Related]

  • 36. Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition.
    Yoon SO, Shin S, Karreth FA, Buel GR, Jedrychowski MP, Plas DR, Dedhar S, Gygi SP, Roux PP, Dephoure N, Blenis J.
    Mol Cell; 2017 Aug 03; 67(3):512-527.e4. PubMed ID: 28757207
    [Abstract] [Full Text] [Related]

  • 37. Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvation-induced autophagy and causes a severe, late-onset myopathy.
    Castets P, Lin S, Rion N, Di Fulvio S, Romanino K, Guridi M, Frank S, Tintignac LA, Sinnreich M, Rüegg MA.
    Cell Metab; 2013 May 07; 17(5):731-44. PubMed ID: 23602450
    [Abstract] [Full Text] [Related]

  • 38. IBP-mediated suppression of autophagy promotes growth and metastasis of breast cancer cells via activating mTORC2/Akt/FOXO3a signaling pathway.
    Chen S, Han Q, Wang X, Yang M, Zhang Z, Li P, Chen A, Hu C, Li S.
    Cell Death Dis; 2013 Oct 10; 4(10):e842. PubMed ID: 24113176
    [Abstract] [Full Text] [Related]

  • 39. Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide.
    Parkhitko AA, Priolo C, Coloff JL, Yun J, Wu JJ, Mizumura K, Xu W, Malinowska IA, Yu J, Kwiatkowski DJ, Locasale JW, Asara JM, Choi AM, Finkel T, Henske EP.
    Mol Cancer Res; 2014 Jan 10; 12(1):48-57. PubMed ID: 24296756
    [Abstract] [Full Text] [Related]

  • 40. Critical role of arachidonic acid-activated mTOR signaling in breast carcinogenesis and angiogenesis.
    Wen ZH, Su YC, Lai PL, Zhang Y, Xu YF, Zhao A, Yao GY, Jia CH, Lin J, Xu S, Wang L, Wang XK, Liu AL, Jiang Y, Dai YF, Bai XC.
    Oncogene; 2013 Jan 10; 32(2):160-70. PubMed ID: 22349822
    [Abstract] [Full Text] [Related]

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