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Journal Abstract Search

277 related items for PubMed ID: 24297300

  • 1. AZD8055 induces cell death associated with autophagy and activation of AMPK in hepatocellular carcinoma.
    Hu M, Huang H, Zhao R, Li P, Li M, Miao H, Chen N, Chen M.
    Oncol Rep; 2014 Feb; 31(2):649-56. PubMed ID: 24297300
    [Abstract] [Full Text] [Related]

  • 2. PM02734 (elisidepsin) induces caspase-independent cell death associated with features of autophagy, inhibition of the Akt/mTOR signaling pathway, and activation of death-associated protein kinase.
    Ling YH, Aracil M, Zou Y, Yuan Z, Lu B, Jimeno J, Cuervo AM, Perez-Soler R.
    Clin Cancer Res; 2011 Aug 15; 17(16):5353-66. PubMed ID: 21690574
    [Abstract] [Full Text] [Related]

  • 3. PARP-1 promotes autophagy via the AMPK/mTOR pathway in CNE-2 human nasopharyngeal carcinoma cells following ionizing radiation, while inhibition of autophagy contributes to the radiation sensitization of CNE-2 cells.
    Chen ZT, Zhao W, Qu S, Li L, Lu XD, Su F, Liang ZG, Guo SY, Zhu XD.
    Mol Med Rep; 2015 Aug 15; 12(2):1868-76. PubMed ID: 25872765
    [Abstract] [Full Text] [Related]

  • 4. AKT serine/threonine protein kinase modulates baicalin-triggered autophagy in human bladder cancer T24 cells.
    Lin C, Tsai SC, Tseng MT, Peng SF, Kuo SC, Lin MW, Hsu YM, Lee MR, Amagaya S, Huang WW, Wu TS, Yang JS.
    Int J Oncol; 2013 Mar 15; 42(3):993-1000. PubMed ID: 23354080
    [Abstract] [Full Text] [Related]

  • 5. Raloxifene induces autophagy-dependent cell death in breast cancer cells via the activation of AMP-activated protein kinase.
    Kim DE, Kim Y, Cho DH, Jeong SY, Kim SB, Suh N, Lee JS, Choi EK, Koh JY, Hwang JJ, Kim CS.
    Mol Cells; 2015 Mar 15; 38(2):138-44. PubMed ID: 25537862
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of mTOR kinase by AZD8055 can antagonize chemotherapy-induced cell death through autophagy induction and down-regulation of p62/sequestosome 1.
    Huang S, Yang ZJ, Yu C, Sinicrope FA.
    J Biol Chem; 2011 Nov 18; 286(46):40002-12. PubMed ID: 21949121
    [Abstract] [Full Text] [Related]

  • 7. Autophagy induced by cardamonin is associated with mTORC1 inhibition in SKOV3 cells.
    Shi D, Niu P, Heng X, Chen L, Zhu Y, Zhou J.
    Pharmacol Rep; 2018 Oct 18; 70(5):908-916. PubMed ID: 30099297
    [Abstract] [Full Text] [Related]

  • 8. Resveratrol induces AMPK and mTOR signaling inhibition-mediated autophagy and apoptosis in multiple myeloma cells.
    Ma R, Yu D, Peng Y, Yi H, Wang Y, Cheng T, Shi B, Yang G, Lai W, Wu X, Lu Y, Shi J.
    Acta Biochim Biophys Sin (Shanghai); 2021 May 21; 53(6):775-783. PubMed ID: 33891090
    [Abstract] [Full Text] [Related]

  • 9. Isoquercitrin induces apoptosis and autophagy in hepatocellular carcinoma cells via AMPK/mTOR/p70S6K signaling pathway.
    Shui L, Wang W, Xie M, Ye B, Li X, Liu Y, Zheng M.
    Aging (Albany NY); 2020 Nov 29; 12(23):24318-24332. PubMed ID: 33260158
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma.
    Shimizu S, Takehara T, Hikita H, Kodama T, Tsunematsu H, Miyagi T, Hosui A, Ishida H, Tatsumi T, Kanto T, Hiramatsu N, Fujita N, Yoshimori T, Hayashi N.
    Int J Cancer; 2012 Aug 01; 131(3):548-57. PubMed ID: 21858812
    [Abstract] [Full Text] [Related]

  • 11. Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway.
    Zhang DM, Liu JS, Deng LJ, Chen MF, Yiu A, Cao HH, Tian HY, Fung KP, Kurihara H, Pan JX, Ye WC.
    Carcinogenesis; 2013 Jun 01; 34(6):1331-42. PubMed ID: 23393227
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of AMPK-dependent autophagy enhances in vitro antiglioma effect of simvastatin.
    Misirkic M, Janjetovic K, Vucicevic L, Tovilovic G, Ristic B, Vilimanovich U, Harhaji-Trajkovic L, Sumarac-Dumanovic M, Micic D, Bumbasirevic V, Trajkovic V.
    Pharmacol Res; 2012 Jan 01; 65(1):111-9. PubMed ID: 21871960
    [Abstract] [Full Text] [Related]

  • 13. Anticancer effects of bufalin on human hepatocellular carcinoma HepG2 cells: roles of apoptosis and autophagy.
    Miao Q, Bi LL, Li X, Miao S, Zhang J, Zhang S, Yang Q, Xie YH, Zhang J, Wang SW.
    Int J Mol Sci; 2013 Jan 11; 14(1):1370-82. PubMed ID: 23344047
    [Abstract] [Full Text] [Related]

  • 14. Dual PI3K/mTOR inhibitor NVP-BEZ235-induced apoptosis of hepatocellular carcinoma cell lines is enhanced by inhibitors of autophagy.
    Chang Z, Shi G, Jin J, Guo H, Guo X, Luo F, Song Y, Jia X.
    Int J Mol Med; 2013 Jun 11; 31(6):1449-56. PubMed ID: 23588698
    [Abstract] [Full Text] [Related]

  • 15. Adenosine monophosphate-activated protein kinase/mammalian target of rapamycin-dependent autophagy protects human dental pulp cells against hypoxia.
    Zhou Q, Liu H, Sun Q, Zhang L, Lin H, Yuan G, Zhang L, Chen Z.
    J Endod; 2013 Jun 11; 39(6):768-73. PubMed ID: 23683277
    [Abstract] [Full Text] [Related]

  • 16. Cucurbitacin E Induces Autophagy via Downregulating mTORC1 Signaling and Upregulating AMPK Activity.
    Zha QB, Zhang XY, Lin QR, Xu LH, Zhao GX, Pan H, Zhou D, Ouyang DY, Liu ZH, He XH.
    PLoS One; 2015 Jun 11; 10(5):e0124355. PubMed ID: 25970614
    [Abstract] [Full Text] [Related]

  • 17. The dual mTORC1 and mTORC2 inhibitor AZD8055 inhibits head and neck squamous cell carcinoma cell growth in vivo and in vitro.
    Li Q, Song XM, Ji YY, Jiang H, Xu LG.
    Biochem Biophys Res Commun; 2013 Nov 01; 440(4):701-6. PubMed ID: 24103749
    [Abstract] [Full Text] [Related]

  • 18. The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia.
    Willems L, Chapuis N, Puissant A, Maciel TT, Green AS, Jacque N, Vignon C, Park S, Guichard S, Herault O, Fricot A, Hermine O, Moura IC, Auberger P, Ifrah N, Dreyfus F, Bonnet D, Lacombe C, Mayeux P, Bouscary D, Tamburini J.
    Leukemia; 2012 Jun 01; 26(6):1195-202. PubMed ID: 22143671
    [Abstract] [Full Text] [Related]

  • 19. The mTORC1/2 Inhibitor AZD8055 Strengthens the Efficiency of the MEK Inhibitor Trametinib to Reduce the Mcl-1/[Bim and Puma] ratio and to Sensitize Ovarian Carcinoma Cells to ABT-737.
    Pétigny-Lechartier C, Duboc C, Jebahi A, Louis MH, Abeilard E, Denoyelle C, Gauduchon P, Poulain L, Villedieu M.
    Mol Cancer Ther; 2017 Jan 01; 16(1):102-115. PubMed ID: 27980105
    [Abstract] [Full Text] [Related]

  • 20. Nilotinib induces autophagy in hepatocellular carcinoma through AMPK activation.
    Yu HC, Lin CS, Tai WT, Liu CY, Shiau CW, Chen KF.
    J Biol Chem; 2013 Jun 21; 288(25):18249-59. PubMed ID: 23677989
    [Abstract] [Full Text] [Related]

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