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Journal Abstract Search

228 related items for PubMed ID: 24352657

  • 1. scyllo-Inositol promotes robust mutant Huntingtin protein degradation.
    Lai AY, Lan CP, Hasan S, Brown ME, McLaurin J.
    J Biol Chem; 2014 Feb 07; 289(6):3666-76. PubMed ID: 24352657
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  • 2. Expanded polyglutamine-containing N-terminal huntingtin fragments are entirely degraded by mammalian proteasomes.
    Juenemann K, Schipper-Krom S, Wiemhoefer A, Kloss A, Sanz Sanz A, Reits EAJ.
    J Biol Chem; 2013 Sep 20; 288(38):27068-27084. PubMed ID: 23908352
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  • 3. Inhibiting the ubiquitin-proteasome system leads to preferential accumulation of toxic N-terminal mutant huntingtin fragments.
    Li X, Wang CE, Huang S, Xu X, Li XJ, Li H, Li S.
    Hum Mol Genet; 2010 Jun 15; 19(12):2445-55. PubMed ID: 20354076
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  • 4. The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation.
    Wong YC, Holzbaur EL.
    J Neurosci; 2014 Jan 22; 34(4):1293-305. PubMed ID: 24453320
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  • 7. Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB-binding protein.
    Jiang H, Nucifora FC, Ross CA, DeFranco DB.
    Hum Mol Genet; 2003 Jan 01; 12(1):1-12. PubMed ID: 12490527
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  • 10. Exploding the Repeat Length Paradigm while Exploring Amyloid Toxicity in Huntington's Disease.
    Wetzel R.
    Acc Chem Res; 2020 Oct 20; 53(10):2347-2357. PubMed ID: 32975927
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  • 12. Clearance of mutant huntingtin.
    Li XJ, Li H, Li S.
    Autophagy; 2010 Jul 20; 6(5):663-4. PubMed ID: 20519964
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  • 13. Degradation of mutant huntingtin via the ubiquitin/proteasome system is modulated by FE65.
    Chow WN, Luk HW, Chan HY, Lau KF.
    Biochem J; 2012 May 01; 443(3):681-9. PubMed ID: 22352297
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  • 14. Extended polyglutamine repeats trigger a feedback loop involving the mitochondrial complex III, the proteasome and huntingtin aggregates.
    Fukui H, Moraes CT.
    Hum Mol Genet; 2007 Apr 01; 16(7):783-97. PubMed ID: 17356014
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  • 16. A structure-based analysis of huntingtin mutant polyglutamine aggregation and toxicity: evidence for a compact beta-sheet structure.
    Poirier MA, Jiang H, Ross CA.
    Hum Mol Genet; 2005 Mar 15; 14(6):765-74. PubMed ID: 15689354
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  • 17. Cdk5 phosphorylation of huntingtin reduces its cleavage by caspases: implications for mutant huntingtin toxicity.
    Luo S, Vacher C, Davies JE, Rubinsztein DC.
    J Cell Biol; 2005 May 23; 169(4):647-56. PubMed ID: 15911879
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