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343 related items for PubMed ID: 24371138

  • 1. Mammalian target of rapamycin (mTOR) inhibition with rapamycin improves cardiac function in type 2 diabetic mice: potential role of attenuated oxidative stress and altered contractile protein expression.
    Das A, Durrant D, Koka S, Salloum FN, Xi L, Kukreja RC.
    J Biol Chem; 2014 Feb 14; 289(7):4145-60. PubMed ID: 24371138
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of mammalian target of rapamycin protects against reperfusion injury in diabetic heart through STAT3 signaling.
    Das A, Salloum FN, Filippone SM, Durrant DE, Rokosh G, Bolli R, Kukreja RC.
    Basic Res Cardiol; 2015 May 14; 110(3):31. PubMed ID: 25911189
    [Abstract] [Full Text] [Related]

  • 3. Chronic treatment with long acting phosphodiesterase-5 inhibitor tadalafil alters proteomic changes associated with cytoskeletal rearrangement and redox regulation in Type 2 diabetic hearts.
    Koka S, Xi L, Kukreja RC.
    Basic Res Cardiol; 2012 Mar 14; 107(2):249. PubMed ID: 22311732
    [Abstract] [Full Text] [Related]

  • 4. Alcohol Dehydrogenase Protects against Endoplasmic Reticulum Stress-Induced Myocardial Contractile Dysfunction via Attenuation of Oxidative Stress and Autophagy: Role of PTEN-Akt-mTOR Signaling.
    Pang J, Fuller ND, Hu N, Barton LA, Henion JM, Guo R, Chen Y, Ren J.
    PLoS One; 2016 Mar 14; 11(1):e0147322. PubMed ID: 26807981
    [Abstract] [Full Text] [Related]

  • 5. Chronic treatment with novel nanoformulated micelles of rapamycin, Rapatar, protects diabetic heart against ischaemia/reperfusion injury.
    Samidurai A, Salloum FN, Durrant D, Chernova OB, Kukreja RC, Das A.
    Br J Pharmacol; 2017 Dec 14; 174(24):4771-4784. PubMed ID: 28967097
    [Abstract] [Full Text] [Related]

  • 6. Mammalian target of rapamycin inhibition attenuates myocardial ischaemia-reperfusion injury in hypertrophic heart.
    Ma LL, Ma X, Kong FJ, Guo JJ, Shi HT, Zhu JB, Zou YZ, Ge JB.
    J Cell Mol Med; 2018 Mar 14; 22(3):1708-1719. PubMed ID: 29314656
    [Abstract] [Full Text] [Related]

  • 7. Phosphodiesterase-5 inhibitor tadalafil attenuates oxidative stress and protects against myocardial ischemia/reperfusion injury in type 2 diabetic mice.
    Koka S, Das A, Salloum FN, Kukreja RC.
    Free Radic Biol Med; 2013 Jul 14; 60():80-8. PubMed ID: 23385031
    [Abstract] [Full Text] [Related]

  • 8. Cardiac energy dependence on glucose increases metabolites related to glutathione and activates metabolic genes controlled by mechanistic target of rapamycin.
    Schisler JC, Grevengoed TJ, Pascual F, Cooper DE, Ellis JM, Paul DS, Willis MS, Patterson C, Jia W, Coleman RA.
    J Am Heart Assoc; 2015 Feb 24; 4(2):. PubMed ID: 25713290
    [Abstract] [Full Text] [Related]

  • 9. Resistin promotes cardiac hypertrophy via the AMP-activated protein kinase/mammalian target of rapamycin (AMPK/mTOR) and c-Jun N-terminal kinase/insulin receptor substrate 1 (JNK/IRS1) pathways.
    Kang S, Chemaly ER, Hajjar RJ, Lebeche D.
    J Biol Chem; 2011 May 27; 286(21):18465-73. PubMed ID: 21478152
    [Abstract] [Full Text] [Related]

  • 10. mTOR-STAT3-notch signalling contributes to ALDH2-induced protection against cardiac contractile dysfunction and autophagy under alcoholism.
    Ge W, Ren J.
    J Cell Mol Med; 2012 Mar 27; 16(3):616-26. PubMed ID: 21609394
    [Abstract] [Full Text] [Related]

  • 11. Impaired cardiac functional reserve in type 2 diabetic db/db mice is associated with metabolic, but not structural, remodelling.
    Daniels A, van Bilsen M, Janssen BJ, Brouns AE, Cleutjens JP, Roemen TH, Schaart G, van der Velden J, van der Vusse GJ, van Nieuwenhoven FA.
    Acta Physiol (Oxf); 2010 Sep 27; 200(1):11-22. PubMed ID: 20175764
    [Abstract] [Full Text] [Related]

  • 12. Curcumin inhibits high glucose‑induced inflammatory injury in human retinal pigment epithelial cells through the ROS‑PI3K/AKT/mTOR signaling pathway.
    Ran Z, Zhang Y, Wen X, Ma J.
    Mol Med Rep; 2019 Feb 27; 19(2):1024-1031. PubMed ID: 30569107
    [Abstract] [Full Text] [Related]

  • 13. Effect of BM 17.0744, a PPARalpha ligand, on the metabolism of perfused hearts from control and diabetic mice.
    Aasum E, Cooper M, Severson DL, Larsen TS.
    Can J Physiol Pharmacol; 2005 Feb 27; 83(2):183-90. PubMed ID: 15791292
    [Abstract] [Full Text] [Related]

  • 14. Treatment of type 2 diabetic db/db mice with a novel PPARgamma agonist improves cardiac metabolism but not contractile function.
    Carley AN, Semeniuk LM, Shimoni Y, Aasum E, Larsen TS, Berger JP, Severson DL.
    Am J Physiol Endocrinol Metab; 2004 Mar 27; 286(3):E449-55. PubMed ID: 14600074
    [Abstract] [Full Text] [Related]

  • 15. Contribution of mammalian target of rapamycin in the pathophysiology of cirrhotic cardiomyopathy.
    Saeedi Saravi SS, Ghazi-Khansari M, Ejtemaei Mehr S, Nobakht M, Mousavi SE, Dehpour AR.
    World J Gastroenterol; 2016 May 21; 22(19):4685-94. PubMed ID: 27217700
    [Abstract] [Full Text] [Related]

  • 16. Discordant signaling and autophagy response to fasting in hearts of obese mice: Implications for ischemia tolerance.
    Andres AM, Kooren JA, Parker SJ, Tucker KC, Ravindran N, Ito BR, Huang C, Venkatraman V, Van Eyk JE, Gottlieb RA, Mentzer RM.
    Am J Physiol Heart Circ Physiol; 2016 Jul 01; 311(1):H219-28. PubMed ID: 27199111
    [Abstract] [Full Text] [Related]

  • 17. Proteomic analysis of mitochondrial proteins in a mouse model of type 2 diabetes.
    Essop MF, Chan WA, Hattingh S.
    Cardiovasc J Afr; 2011 Jul 01; 22(4):175-8. PubMed ID: 20859605
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of PI-3 kinase/Akt/mTOR, but not calcineurin signaling, reverses insulin-like growth factor I-induced protection against glucose toxicity in cardiomyocyte contractile function.
    Li SY, Fang CX, Aberle NS, Ren BH, Ceylan-Isik AF, Ren J.
    J Endocrinol; 2005 Sep 01; 186(3):491-503. PubMed ID: 16135669
    [Abstract] [Full Text] [Related]

  • 19. mTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes.
    Fraenkel M, Ketzinel-Gilad M, Ariav Y, Pappo O, Karaca M, Castel J, Berthault MF, Magnan C, Cerasi E, Kaiser N, Leibowitz G.
    Diabetes; 2008 Apr 01; 57(4):945-57. PubMed ID: 18174523
    [Abstract] [Full Text] [Related]

  • 20. CD74 ablation rescues type 2 diabetes mellitus-induced cardiac remodeling and contractile dysfunction through pyroptosis-evoked regulation of ferroptosis.
    Chen L, Yin Z, Qin X, Zhu X, Chen X, Ding G, Sun D, Wu NN, Fei J, Bi Y, Zhang J, Bucala R, Ren J, Zheng Q.
    Pharmacol Res; 2022 Feb 01; 176():106086. PubMed ID: 35033649
    [Abstract] [Full Text] [Related]


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