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147 related items for PubMed ID: 24383450

  • 1. Development of a thyroperoxidase inhibition assay for high-throughput screening.
    Paul KB, Hedge JM, Rotroff DM, Hornung MW, Crofton KM, Simmons SO.
    Chem Res Toxicol; 2014 Mar 17; 27(3):387-99. PubMed ID: 24383450
    [Abstract] [Full Text] [Related]

  • 2. Cross-species analysis of thyroperoxidase inhibition by xenobiotics demonstrates conservation of response between pig and rat.
    Paul KB, Hedge JM, Macherla C, Filer DL, Burgess E, Simmons SO, Crofton KM, Hornung MW.
    Toxicology; 2013 Oct 04; 312():97-107. PubMed ID: 23959146
    [Abstract] [Full Text] [Related]

  • 3. Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries.
    Paul Friedman K, Watt ED, Hornung MW, Hedge JM, Judson RS, Crofton KM, Houck KA, Simmons SO.
    Toxicol Sci; 2016 May 04; 151(1):160-80. PubMed ID: 26884060
    [Abstract] [Full Text] [Related]

  • 4. Extrapolating In Vitro Screening Assay Data for Thyroperoxidase Inhibition to Predict Serum Thyroid Hormones in the Rat.
    Hassan I, El-Masri H, Ford J, Brennan A, Handa S, Paul Friedman K, Gilbert ME.
    Toxicol Sci; 2020 Feb 01; 173(2):280-292. PubMed ID: 31697382
    [Abstract] [Full Text] [Related]

  • 5. A comparison of potency differences among thyroid peroxidase (TPO) inhibitors to induce developmental toxicity and other thyroid gland-linked toxicities in humans and rats.
    Motonaga K, Ota M, Odawara K, Saito S, Welsch F.
    Regul Toxicol Pharmacol; 2016 Oct 01; 80():283-90. PubMed ID: 27350053
    [Abstract] [Full Text] [Related]

  • 6. A high throughput screening assay for human Thyroperoxidase inhibitors.
    Dong H, Friedman KP, Filiatreault A, Thomson EM, Wade MG.
    Toxicol In Vitro; 2024 Dec 01; 101():105946. PubMed ID: 39349109
    [Abstract] [Full Text] [Related]

  • 7. In vitro assessment of thyroid peroxidase inhibition by chemical exposure: comparison of cell models and detection methods.
    Liu R, Novák J, Hilscherová K.
    Arch Toxicol; 2024 Aug 01; 98(8):2631-2645. PubMed ID: 38796608
    [Abstract] [Full Text] [Related]

  • 8. Changes in thyroid peroxidase activity in response to various chemicals.
    Song M, Kim YJ, Park YK, Ryu JC.
    J Environ Monit; 2012 Aug 01; 14(8):2121-6. PubMed ID: 22699773
    [Abstract] [Full Text] [Related]

  • 9. An assay for screening xenobiotics for inhibition of rat thyroid gland peroxidase activity.
    Price RJ, Burch R, Chatham LR, Higgins LG, Currie RA, Lake BG.
    Xenobiotica; 2020 Mar 01; 50(3):318-322. PubMed ID: 31180273
    [Abstract] [Full Text] [Related]

  • 10. Effect of antithyroid agents 6-propyl-2-thiouracil and 1-mehtyl-2-mercaptoimidazole on human thyroid iodine peroxidase.
    Nagasaka A, Hidaka H.
    J Clin Endocrinol Metab; 1976 Jul 01; 43(1):152-8. PubMed ID: 947933
    [Abstract] [Full Text] [Related]

  • 11. A rapid assay of human thyroid peroxidase activity.
    Dong H, Godlewska M, Wade MG.
    Toxicol In Vitro; 2020 Feb 01; 62():104662. PubMed ID: 31629072
    [Abstract] [Full Text] [Related]

  • 12. Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling.
    Leonard JA, Tan YM, Gilbert M, Isaacs K, El-Masri H.
    Toxicol Sci; 2016 May 01; 151(1):57-70. PubMed ID: 26865668
    [Abstract] [Full Text] [Related]

  • 13. Methimazole and propylthiouracil increase cellular thyroid peroxidase activity and thyroid peroxidase mRNA in cultured porcine thyroid follicles.
    Sugawara M, Sugawara Y, Wen K.
    Thyroid; 1999 May 01; 9(5):513-8. PubMed ID: 10365684
    [Abstract] [Full Text] [Related]

  • 14. Thyroid organotypic rat and human cultures used to investigate drug effects on thyroid function, hormone synthesis and release pathways.
    Vickers AE, Heale J, Sinclair JR, Morris S, Rowe JM, Fisher RL.
    Toxicol Appl Pharmacol; 2012 Apr 01; 260(1):81-8. PubMed ID: 22342233
    [Abstract] [Full Text] [Related]

  • 15. Perinatal exposure to the thyroperoxidase inhibitors methimazole and amitrole perturbs thyroid hormone system signaling and alters motor activity in rat offspring.
    Ramhøj L, Svingen T, Frädrich C, Rijntjes E, Wirth EK, Pedersen K, Köhrle J, Axelstad M.
    Toxicol Lett; 2022 Jan 01; 354():44-55. PubMed ID: 34757178
    [Abstract] [Full Text] [Related]

  • 16. Metabolism of 35S- and 14C-labeled 1-methyl-2-mercaptoimidazole in vitro and in vivo.
    Taurog A, Dorris ML, Guziec FS.
    Endocrinology; 1989 Jan 01; 124(1):30-9. PubMed ID: 2535809
    [Abstract] [Full Text] [Related]

  • 17. Mechanism of inactivation of thyroid peroxidase by thioureylene drugs.
    Engler H, Taurog A, Nakashima T.
    Biochem Pharmacol; 1982 Dec 01; 31(23):3801-6. PubMed ID: 6186257
    [Abstract] [Full Text] [Related]

  • 18. Studies on the goitrogenic mechanism of action of N,N,N',N'-tetramethylthiourea.
    Freyberger A, Ahr HJ.
    Toxicology; 2006 Jan 16; 217(2-3):169-75. PubMed ID: 16297522
    [Abstract] [Full Text] [Related]

  • 19. Mechanism of action of thioureylene antithyroid drugs in the rat: possible inactivation of thyroid peroxidase by propylthiouracil.
    Shiroozu A, Taurog A, Engler H, Dorris ML.
    Endocrinology; 1983 Jul 16; 113(1):362-70. PubMed ID: 6861708
    [Abstract] [Full Text] [Related]

  • 20. The mechanism of action of the thioureylene antithyroid drugs.
    Taurog A.
    Endocrinology; 1976 Apr 16; 98(4):1031-46. PubMed ID: 1278093
    [Abstract] [Full Text] [Related]

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