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Journal Abstract Search

202 related items for PubMed ID: 24403076

  • 1. Ligand independence of the T618I mutation in the colony-stimulating factor 3 receptor (CSF3R) protein results from loss of O-linked glycosylation and increased receptor dimerization.
    Maxson JE, Luty SB, MacManiman JD, Abel ML, Druker BJ, Tyner JW.
    J Biol Chem; 2014 Feb 28; 289(9):5820-7. PubMed ID: 24403076
    [Abstract] [Full Text] [Related]

  • 2. T618I CSF3R mutations in chronic neutrophilic leukemia induce oncogenic signals through aberrant trafficking and constitutive phosphorylation of the O-glycosylated receptor form.
    Price A, Druhan LJ, Lance A, Clark G, Vestal CG, Zhang Q, Foureau D, Parsons J, Hamilton A, Steuerwald NM, Avalos BR.
    Biochem Biophys Res Commun; 2020 Feb 26; 523(1):208-213. PubMed ID: 31848046
    [Abstract] [Full Text] [Related]

  • 3. The Colony-Stimulating Factor 3 Receptor T640N Mutation Is Oncogenic, Sensitive to JAK Inhibition, and Mimics T618I.
    Maxson JE, Luty SB, MacManiman JD, Paik JC, Gotlib J, Greenberg P, Bahamadi S, Savage SL, Abel ML, Eide CA, Loriaux MM, Stevens EA, Tyner JW.
    Clin Cancer Res; 2016 Feb 01; 22(3):757-64. PubMed ID: 26475333
    [Abstract] [Full Text] [Related]

  • 4. A Novel Germline Variant in CSF3R Reduces N-Glycosylation and Exerts Potent Oncogenic Effects in Leukemia.
    Spiciarich DR, Oh ST, Foley A, Hughes SB, Mauro MJ, Abdel-Wahab O, Press RD, Viner R, Thompson SL, Chen Q, Azadi P, Bertozzi CR, Maxson JE.
    Cancer Res; 2018 Dec 15; 78(24):6762-6770. PubMed ID: 30348809
    [Abstract] [Full Text] [Related]

  • 5. Mutational screens highlight glycosylation as a modulator of colony-stimulating factor 3 receptor (CSF3R) activity.
    Hollander MJ, Malaker SA, Riley NM, Perez I, Abney NM, Gray MA, Maxson JE, Cochran JR, Bertozzi CR.
    J Biol Chem; 2023 Jun 15; 299(6):104755. PubMed ID: 37116708
    [Abstract] [Full Text] [Related]

  • 6. Gain-of-function mutations in granulocyte colony-stimulating factor receptor (CSF3R) reveal distinct mechanisms of CSF3R activation.
    Zhang H, Coblentz C, Watanabe-Smith K, Means S, Means J, Maxson JE, Tyner JW.
    J Biol Chem; 2018 May 11; 293(19):7387-7396. PubMed ID: 29572350
    [Abstract] [Full Text] [Related]

  • 7. CSF3R is mutated in chronic neutrophilic leukemia and atypical CML.
    Cancer Discov; 2013 Jul 11; 3(7):OF23. PubMed ID: 23847367
    [Abstract] [Full Text] [Related]

  • 8. Co-Occurring CSF3R W791* Germline and Somatic T618I Driver Mutations Induce Early CNL and Clonal Progression to Mixed Phenotype Acute Leukemia.
    Adam FC, Szybinski J, Halter JP, Cantoni N, Wenzel F, Leonards K, Brkic S, Passweg JR, Touw I, Maxson JE, Meyer SC.
    Curr Oncol; 2022 Feb 01; 29(2):805-815. PubMed ID: 35200567
    [Abstract] [Full Text] [Related]

  • 9. CSF3R T618I is a highly prevalent and specific mutation in chronic neutrophilic leukemia.
    Pardanani A, Lasho TL, Laborde RR, Elliott M, Hanson CA, Knudson RA, Ketterling RP, Maxson JE, Tyner JW, Tefferi A.
    Leukemia; 2013 Sep 01; 27(9):1870-3. PubMed ID: 23604229
    [Abstract] [Full Text] [Related]

  • 10. CSF3R mutated myeloid neoplasms: Beyond chronic neutrophilic leukemia.
    Mohamed A, Gao J, Chen YH, Abaza Y, Altman J, Jennings L, Vormittag-Nocito E, Sukhanova M, Lu X, Chen Q.
    Hum Pathol; 2024 Jul 01; 149():66-74. PubMed ID: 38879086
    [Abstract] [Full Text] [Related]

  • 11. Clinical significance of CSF3R, SRSF2 and SETBP1 mutations in chronic neutrophilic leukemia and chronic myelomonocytic leukemia.
    Ouyang Y, Qiao C, Chen Y, Zhang SJ.
    Oncotarget; 2017 Mar 28; 8(13):20834-20841. PubMed ID: 28209919
    [Abstract] [Full Text] [Related]

  • 12. Chronic neutrophilic leukemia in a child with a CSF3R T618I germ line mutation.
    Druhan LJ, McMahon DP, Steuerwald N, Price AE, Lance A, Gerber JM, Avalos BR.
    Blood; 2016 Oct 20; 128(16):2097-2099. PubMed ID: 27581359
    [No Abstract] [Full Text] [Related]

  • 13. Molecular response of CSF3R T618I harboring chronic neutrophilic leukemia after induction chemotherapy linked to cord blood transplantation.
    Kawashima I, Kumagai T, Suzuki M, Suzuki J, Koshiishi M, Nakajima K, Kirito K.
    Ann Hematol; 2019 Sep 20; 98(9):2249-2250. PubMed ID: 31240470
    [No Abstract] [Full Text] [Related]

  • 14. A CSF3R T618I Mutation in a Patient with Chronic Neutrophilic Leukemia and Severe Bleeding Complications.
    Mitsumori T, Komatsu N, Kirito K.
    Intern Med; 2016 Sep 20; 55(4):405-7. PubMed ID: 26875968
    [Abstract] [Full Text] [Related]

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  • 16. Genomics of chronic neutrophilic leukemia.
    Maxson JE, Tyner JW.
    Blood; 2017 Feb 09; 129(6):715-722. PubMed ID: 28028025
    [Abstract] [Full Text] [Related]

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  • 18. Coexisting of bone marrow fibrosis, dysplasia and an X chromosomal abnormality in chronic neutrophilic leukemia with CSF3R mutation: a case report and literature review.
    Wu XB, Wu WW, Zhou Y, Wang X, Li J, Yu Y.
    BMC Cancer; 2018 Mar 27; 18(1):343. PubMed ID: 29587671
    [Abstract] [Full Text] [Related]

  • 19. Inherited transmission of the CSF3R T618I mutational hotspot in familial chronic neutrophilic leukemia.
    Duployez N, Willekens C, Plo I, Marceau-Renaut A, de Botton S, Fenwarth L, Boyer T, Huet G, Nibourel O, Rose C, Nelken B, Quesnel B, Preudhomme C.
    Blood; 2019 Dec 26; 134(26):2414-2416. PubMed ID: 31697825
    [No Abstract] [Full Text] [Related]

  • 20. The CSF3R T618I mutation causes a lethal neutrophilic neoplasia in mice that is responsive to therapeutic JAK inhibition.
    Fleischman AG, Maxson JE, Luty SB, Agarwal A, Royer LR, Abel ML, MacManiman JD, Loriaux MM, Druker BJ, Tyner JW.
    Blood; 2013 Nov 21; 122(22):3628-31. PubMed ID: 24081659
    [Abstract] [Full Text] [Related]

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