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Journal Abstract Search

288 related items for PubMed ID: 24421394

  • 1. Loss of von Hippel-Lindau protein (VHL) increases systemic cholesterol levels through targeting hypoxia-inducible factor 2α and regulation of bile acid homeostasis.
    Ramakrishnan SK, Taylor M, Qu A, Ahn SH, Suresh MV, Raghavendran K, Gonzalez FJ, Shah YM.
    Mol Cell Biol; 2014 Apr; 34(7):1208-20. PubMed ID: 24421394
    [Abstract] [Full Text] [Related]

  • 2. Renal tubular HIF-2α expression requires VHL inactivation and causes fibrosis and cysts.
    Schietke RE, Hackenbeck T, Tran M, Günther R, Klanke B, Warnecke CL, Knaup KX, Shukla D, Rosenberger C, Koesters R, Bachmann S, Betz P, Schley G, Schödel J, Willam C, Winkler T, Amann K, Eckardt KU, Maxwell P, Wiesener MS.
    PLoS One; 2012 Apr; 7(1):e31034. PubMed ID: 22299048
    [Abstract] [Full Text] [Related]

  • 3. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
    Krieg M, Haas R, Brauch H, Acker T, Flamme I, Plate KH.
    Oncogene; 2000 Nov 16; 19(48):5435-43. PubMed ID: 11114720
    [Abstract] [Full Text] [Related]

  • 4. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
    Carroll VA, Ashcroft M.
    Cancer Res; 2006 Jun 15; 66(12):6264-70. PubMed ID: 16778202
    [Abstract] [Full Text] [Related]

  • 5. Hypoxia-inducible factor-2α mediates the adaptive increase of intestinal ferroportin during iron deficiency in mice.
    Taylor M, Qu A, Anderson ER, Matsubara T, Martin A, Gonzalez FJ, Shah YM.
    Gastroenterology; 2011 Jun 15; 140(7):2044-55. PubMed ID: 21419768
    [Abstract] [Full Text] [Related]

  • 6. Action of hypoxia-inducible factor in liver and kidney from mice with Pax8-rtTA-based deletion of von Hippel-Lindau protein.
    Mathia S, Paliege A, Koesters R, Peters H, Neumayer HH, Bachmann S, Rosenberger C.
    Acta Physiol (Oxf); 2013 Mar 15; 207(3):565-76. PubMed ID: 23384425
    [Abstract] [Full Text] [Related]

  • 7. Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma.
    Osada R, Horiuchi A, Kikuchi N, Yoshida J, Hayashi A, Ota M, Katsuyama Y, Melillo G, Konishi I.
    Hum Pathol; 2007 Sep 15; 38(9):1310-20. PubMed ID: 17555795
    [Abstract] [Full Text] [Related]

  • 8. The relationship of erythropoietin overexpression with von Hippel-Lindau tumour suppressor gene mutations between hypoxia-inducible factor-1α and -2α in sporadic clear cell renal carcinoma.
    Gong K, Zhang N, Zhang K, Na Y.
    Int J Mol Med; 2010 Dec 15; 26(6):907-12. PubMed ID: 21042786
    [Abstract] [Full Text] [Related]

  • 9. Reduction of hepatic fibrosis by overexpression of von Hippel-Lindau protein in experimental models of chronic liver disease.
    Wang J, Lu Z, Xu Z, Tian P, Miao H, Pan S, Song R, Sun X, Zhao B, Wang D, Ma Y, Song X, Zhang S, Liu L, Jiang H.
    Sci Rep; 2017 Jan 23; 7():41038. PubMed ID: 28112200
    [Abstract] [Full Text] [Related]

  • 10. Fibrosis and hypoxia-inducible factor-1α-dependent tumors of the soft tissue on loss of von Hippel-Lindau in mesenchymal progenitors.
    Mangiavini L, Merceron C, Araldi E, Khatri R, Gerard-O'Riley R, Wilson TL, Sandusky G, Abadie J, Lyons KM, Giaccia AJ, Schipani E.
    Am J Pathol; 2015 Nov 23; 185(11):3090-101. PubMed ID: 26348575
    [Abstract] [Full Text] [Related]

  • 11. Hif-2α promotes degradation of mammalian peroxisomes by selective autophagy.
    Walter KM, Schönenberger MJ, Trötzmüller M, Horn M, Elsässer HP, Moser AB, Lucas MS, Schwarz T, Gerber PA, Faust PL, Moch H, Köfeler HC, Krek W, Kovacs WJ.
    Cell Metab; 2014 Nov 04; 20(5):882-897. PubMed ID: 25440060
    [Abstract] [Full Text] [Related]

  • 12. Hydrogen sulfide inhibits hypoxia- but not anoxia-induced hypoxia-inducible factor 1 activation in a von hippel-lindau- and mitochondria-dependent manner.
    Kai S, Tanaka T, Daijo H, Harada H, Kishimoto S, Suzuki K, Takabuchi S, Takenaga K, Fukuda K, Hirota K.
    Antioxid Redox Signal; 2012 Feb 01; 16(3):203-16. PubMed ID: 22004513
    [Abstract] [Full Text] [Related]

  • 13. Beluga whale pVHL enhances HIF-2α activity via inducing HIF-2α proteasomal degradation under hypoxia.
    Bi J, Hu B, Wang J, Liu X, Zheng J, Wang D, Xiao W.
    Oncotarget; 2017 Jun 27; 8(26):42272-42287. PubMed ID: 28178687
    [Abstract] [Full Text] [Related]

  • 14. PTEN suppression of YY1 induces HIF-2 activity in von-Hippel-Lindau-null renal-cell carcinoma.
    Petrella BL, Brinckerhoff CE.
    Cancer Biol Ther; 2009 Jul 27; 8(14):1389-401. PubMed ID: 19483472
    [Abstract] [Full Text] [Related]

  • 15. Kelch-like 20 up-regulates the expression of hypoxia-inducible factor-2α through hypoxia- and von Hippel-Lindau tumor suppressor protein-independent regulatory mechanisms.
    Higashimura Y, Terai T, Yamaji R, Mitani T, Ogawa M, Harada N, Inui H, Nakano Y.
    Biochem Biophys Res Commun; 2011 Sep 23; 413(2):201-5. PubMed ID: 21888897
    [Abstract] [Full Text] [Related]

  • 16. [The expression of hypoxia inducible factor-1,2 alpha in sporadic clear cell renal cell carcinoma and their relationships to the mutations of von Hippel-Lindau gene].
    Gong K, Zhang N, Na X, Wu G, Yang XY, Xin DQ, Na YQ.
    Zhonghua Wai Ke Za Zhi; 2005 Mar 15; 43(6):390-3. PubMed ID: 15854350
    [Abstract] [Full Text] [Related]

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  • 18. Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha.
    Duez H, van der Veen JN, Duhem C, Pourcet B, Touvier T, Fontaine C, Derudas B, Baugé E, Havinga R, Bloks VW, Wolters H, van der Sluijs FH, Vennström B, Kuipers F, Staels B.
    Gastroenterology; 2008 Aug 15; 135(2):689-98. PubMed ID: 18565334
    [Abstract] [Full Text] [Related]

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  • 20. Epigenetic regulation of HIF-1α in renal cancer cells involves HIF-1α/2α binding to a reverse hypoxia-response element.
    Xu J, Wang B, Xu Y, Sun L, Tian W, Shukla D, Barod R, Grillari J, Grillari-Voglauer R, Maxwell PH, Esteban MA.
    Oncogene; 2012 Feb 23; 31(8):1065-72. PubMed ID: 21841824
    [Abstract] [Full Text] [Related]

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