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Journal Abstract Search

515 related items for PubMed ID: 24450438

  • 1. Targeting the hedgehog-glioma-associated oncogene homolog pathway inhibits bleomycin-induced lung fibrosis in mice.
    Moshai EF, Wémeau-Stervinou L, Cigna N, Brayer S, Sommé JM, Crestani B, Mailleux AA.
    Am J Respir Cell Mol Biol; 2014 Jul; 51(1):11-25. PubMed ID: 24450438
    [Abstract] [Full Text] [Related]

  • 2. The transcription factor GLI2 as a downstream mediator of transforming growth factor-β-induced fibroblast activation in SSc.
    Liang R, Šumová B, Cordazzo C, Mallano T, Zhang Y, Wohlfahrt T, Dees C, Ramming A, Krasowska D, Michalska-Jakubus M, Distler O, Schett G, Šenolt L, Distler JH.
    Ann Rheum Dis; 2017 Apr; 76(4):756-764. PubMed ID: 27793816
    [Abstract] [Full Text] [Related]

  • 3. Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo.
    Wickström M, Dyberg C, Shimokawa T, Milosevic J, Baryawno N, Fuskevåg OM, Larsson R, Kogner P, Zaphiropoulos PG, Johnsen JI.
    Int J Cancer; 2013 Apr 01; 132(7):1516-24. PubMed ID: 22949014
    [Abstract] [Full Text] [Related]

  • 4. Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro.
    You M, Varona-Santos J, Singh S, Robbins DJ, Savaraj N, Nguyen DM.
    J Thorac Cardiovasc Surg; 2014 Jan 01; 147(1):508-16. PubMed ID: 24094913
    [Abstract] [Full Text] [Related]

  • 5. The Hedgehog target Gli1 is not required for bleomycin-induced lung fibrosis.
    Kugler MC, Yie TA, Cai Y, Berger JZ, Loomis CA, Munger JS.
    Exp Lung Res; 2019 Jan 01; 45(1-2):22-29. PubMed ID: 30982371
    [Abstract] [Full Text] [Related]

  • 6. The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury.
    Grzelak CA, Martelotto LG, Sigglekow ND, Patkunanathan B, Ajami K, Calabro SR, Dwyer BJ, Tirnitz-Parker JE, Watkins DN, Warner FJ, Shackel NA, McCaughan GW.
    J Hepatol; 2014 Jan 01; 60(1):143-51. PubMed ID: 23978713
    [Abstract] [Full Text] [Related]

  • 7. NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200.
    Fu J, Rodova M, Nanta R, Meeker D, Van Veldhuizen PJ, Srivastava RK, Shankar S.
    Neuro Oncol; 2013 Jun 01; 15(6):691-706. PubMed ID: 23482671
    [Abstract] [Full Text] [Related]

  • 8. In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.
    Benvenuto M, Masuelli L, De Smaele E, Fantini M, Mattera R, Cucchi D, Bonanno E, Di Stefano E, Frajese GV, Orlandi A, Screpanti I, Gulino A, Modesti A, Bei R.
    Oncotarget; 2016 Feb 23; 7(8):9250-70. PubMed ID: 26843616
    [Abstract] [Full Text] [Related]

  • 9. Targeting hedgehog signaling pathway in pediatric tumors: in vitro evaluation of SMO and GLI inhibitors.
    Arnhold V, Boos J, Lanvers-Kaminsky C.
    Cancer Chemother Pharmacol; 2016 Mar 23; 77(3):495-505. PubMed ID: 26781311
    [Abstract] [Full Text] [Related]

  • 10. Gant61 ameliorates CCl4-induced liver fibrosis by inhibition of Hedgehog signaling activity.
    Jiayuan S, Junyan Y, Xiangzhen W, Zuping L, Jian N, Baowei H, Lifang J.
    Toxicol Appl Pharmacol; 2020 Jan 15; 387():114853. PubMed ID: 31816328
    [Abstract] [Full Text] [Related]

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  • 13. Role of Sonic Hedgehog in idiopathic pulmonary fibrosis.
    Bolaños AL, Milla CM, Lira JC, Ramírez R, Checa M, Barrera L, García-Alvarez J, Carbajal V, Becerril C, Gaxiola M, Pardo A, Selman M.
    Am J Physiol Lung Cell Mol Physiol; 2012 Dec 01; 303(11):L978-90. PubMed ID: 23023967
    [Abstract] [Full Text] [Related]

  • 14. Regulation of DNA damage following termination of Hedgehog (HH) survival signaling at the level of the GLI genes in human colon cancer.
    Agyeman A, Mazumdar T, Houghton JA.
    Oncotarget; 2012 Aug 01; 3(8):854-68. PubMed ID: 23097684
    [Abstract] [Full Text] [Related]

  • 15. GANT-61 and GDC-0449 induce apoptosis of prostate cancer stem cells through a GLI-dependent mechanism.
    Tong W, Qiu L, Qi M, Liu J, Hu K, Lin W, Huang Y, Fu J.
    J Cell Biochem; 2018 Apr 01; 119(4):3641-3652. PubMed ID: 29231999
    [Abstract] [Full Text] [Related]

  • 16. Effects of the hedgehog inhibitor GDC-0449, alone or in combination with dasatinib, on BCR-ABL-positive leukemia cells.
    Okabe S, Tauchi T, Tanaka Y, Katagiri S, Ohyashiki K.
    Stem Cells Dev; 2012 Nov 01; 21(16):2939-48. PubMed ID: 22642671
    [Abstract] [Full Text] [Related]

  • 17. Pharmacological inhibition of the Hedgehog pathway prevents human rhabdomyosarcoma cell growth.
    Kawabata N, Ijiri K, Ishidou Y, Yamamoto T, Nagao H, Nagano S, Maeda S, Komiya S, Setoguchi T.
    Int J Oncol; 2011 Oct 01; 39(4):899-906. PubMed ID: 21674124
    [Abstract] [Full Text] [Related]

  • 18. The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer.
    Mazumdar T, DeVecchio J, Agyeman A, Shi T, Houghton JA.
    Oncotarget; 2011 Aug 01; 2(8):638-45. PubMed ID: 21860067
    [Abstract] [Full Text] [Related]

  • 19. Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects.
    Wellbrock J, Latuske E, Köhler J, Wagner K, Stamm H, Vettorazzi E, Vohwinkel G, Klokow M, Uibeleisen R, Ehm P, Riecken K, Loges S, Thol F, Schubert C, Amling M, Jücker M, Bokemeyer C, Heuser M, Krauter J, Fiedler W.
    Clin Cancer Res; 2015 May 15; 21(10):2388-98. PubMed ID: 25745035
    [Abstract] [Full Text] [Related]

  • 20. Gli as a novel therapeutic target in malignant pleural mesothelioma.
    Li H, Lui N, Cheng T, Tseng HH, Yue D, Giroux-Leprieur E, Do HT, Sheng Q, Jin JQ, Luh TW, Jablons DM, He B.
    PLoS One; 2013 May 15; 8(3):e57346. PubMed ID: 23483902
    [Abstract] [Full Text] [Related]

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