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Journal Abstract Search


268 related items for PubMed ID: 24469394

  • 1. Stat5 regulates the phosphatidylinositol 3-kinase/Akt1 pathway during mammary gland development and tumorigenesis.
    Schmidt JW, Wehde BL, Sakamoto K, Triplett AA, Anderson SM, Tsichlis PN, Leone G, Wagner KU.
    Mol Cell Biol; 2014 Apr; 34(7):1363-77. PubMed ID: 24469394
    [Abstract] [Full Text] [Related]

  • 2. Crosstalk between STAT5 activation and PI3K/AKT functions in normal and transformed mammary epithelial cells.
    Rädler PD, Wehde BL, Wagner KU.
    Mol Cell Endocrinol; 2017 Aug 15; 451():31-39. PubMed ID: 28495456
    [Abstract] [Full Text] [Related]

  • 3. Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis.
    Mancini ML, Lien EC, Toker A.
    Oncotarget; 2016 Apr 05; 7(14):17301-13. PubMed ID: 27004402
    [Abstract] [Full Text] [Related]

  • 4. Autocrine prolactin induced by the Pten-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways.
    Chen CC, Stairs DB, Boxer RB, Belka GK, Horseman ND, Alvarez JV, Chodosh LA.
    Genes Dev; 2012 Oct 01; 26(19):2154-68. PubMed ID: 23028142
    [Abstract] [Full Text] [Related]

  • 5. Stat5 promotes survival of mammary epithelial cells through transcriptional activation of a distinct promoter in Akt1.
    Creamer BA, Sakamoto K, Schmidt JW, Triplett AA, Moriggl R, Wagner KU.
    Mol Cell Biol; 2010 Jun 01; 30(12):2957-70. PubMed ID: 20385773
    [Abstract] [Full Text] [Related]

  • 6. CUZD1 is a critical mediator of the JAK/STAT5 signaling pathway that controls mammary gland development during pregnancy.
    Mapes J, Li Q, Kannan A, Anandan L, Laws M, Lydon JP, Bagchi IC, Bagchi MK.
    PLoS Genet; 2017 Mar 01; 13(3):e1006654. PubMed ID: 28278176
    [Abstract] [Full Text] [Related]

  • 7. ErbB3 drives mammary epithelial survival and differentiation during pregnancy and lactation.
    Williams MM, Vaught DB, Joly MM, Hicks DJ, Sanchez V, Owens P, Rahman B, Elion DL, Balko JM, Cook RS.
    Breast Cancer Res; 2017 Sep 08; 19(1):105. PubMed ID: 28886748
    [Abstract] [Full Text] [Related]

  • 8. Akt is required for Stat5 activation and mammary differentiation.
    Chen CC, Boxer RB, Stairs DB, Portocarrero CP, Horton RH, Alvarez JV, Birnbaum MJ, Chodosh LA.
    Breast Cancer Res; 2010 Sep 08; 12(5):R72. PubMed ID: 20849614
    [Abstract] [Full Text] [Related]

  • 9. Constitutive activation of JAK2 in mammary epithelium elevates Stat5 signalling, promotes alveologenesis and resistance to cell death, and contributes to tumourigenesis.
    Caffarel MM, Zaragoza R, Pensa S, Li J, Green AR, Watson CJ.
    Cell Death Differ; 2012 Mar 08; 19(3):511-22. PubMed ID: 21941370
    [Abstract] [Full Text] [Related]

  • 10. Mutation of thyroid hormone receptor-β in mice predisposes to the development of mammary tumors.
    Guigon CJ, Kim DW, Willingham MC, Cheng SY.
    Oncogene; 2011 Jul 28; 30(30):3381-90. PubMed ID: 21399657
    [Abstract] [Full Text] [Related]

  • 11. Exploring the gain of function contribution of AKT to mammary tumorigenesis in mouse models.
    Blanco-Aparicio C, Cañamero M, Cecilia Y, Pequeño B, Renner O, Ferrer I, Carnero A.
    PLoS One; 2010 Feb 19; 5(2):e9305. PubMed ID: 20174572
    [Abstract] [Full Text] [Related]

  • 12. PI3K-p110α mediates resistance to HER2-targeted therapy in HER2+, PTEN-deficient breast cancers.
    Wang Q, Liu P, Spangle JM, Von T, Roberts TM, Lin NU, Krop IE, Winer EP, Zhao JJ.
    Oncogene; 2016 Jul 07; 35(27):3607-12. PubMed ID: 26500061
    [Abstract] [Full Text] [Related]

  • 13. Prolactin regulates ZNT2 expression through the JAK2/STAT5 signaling pathway in mammary cells.
    Qian L, Lopez V, Seo YA, Kelleher SL.
    Am J Physiol Cell Physiol; 2009 Aug 07; 297(2):C369-77. PubMed ID: 19494234
    [Abstract] [Full Text] [Related]

  • 14. Overexpression of the tumor suppressor gene phosphatase and tensin homologue partially inhibits wnt-1-induced mammary tumorigenesis.
    Zhao H, Cui Y, Dupont J, Sun H, Hennighausen L, Yakar S.
    Cancer Res; 2005 Aug 01; 65(15):6864-73. PubMed ID: 16061670
    [Abstract] [Full Text] [Related]

  • 15. Cyclophilin A Function in Mammary Epithelium Impacts Jak2/Stat5 Signaling, Morphogenesis, Differentiation, and Tumorigenesis in the Mammary Gland.
    Volker SE, Hedrick SE, Feeney YB, Clevenger CV.
    Cancer Res; 2018 Jul 15; 78(14):3877-3887. PubMed ID: 29959151
    [Abstract] [Full Text] [Related]

  • 16. Novel mechanism for Fc{epsilon}RI-mediated signal transducer and activator of transcription 5 (STAT5) tyrosine phosphorylation and the selective influence of STAT5B over mast cell cytokine production.
    Pullen NA, Barnstein BO, Falanga YT, Wang Z, Suzuki R, Tamang TD, Khurana MC, Harry EA, Draber P, Bunting KD, Mizuno K, Wilson BS, Ryan JJ.
    J Biol Chem; 2012 Jan 13; 287(3):2045-54. PubMed ID: 22130676
    [Abstract] [Full Text] [Related]

  • 17. The gene dosage of class Ia PI3K dictates the development of PTEN hamartoma tumor syndrome.
    Wang Q, Weisberg E, Zhao JJ.
    Cell Cycle; 2013 Dec 01; 12(23):3589-93. PubMed ID: 24131925
    [Abstract] [Full Text] [Related]

  • 18. Zinc Finger Homeodomain Factor Zfhx3 Is Essential for Mammary Lactogenic Differentiation by Maintaining Prolactin Signaling Activity.
    Zhao D, Ma G, Zhang X, He Y, Li M, Han X, Fu L, Dong XY, Nagy T, Zhao Q, Fu L, Dong JT.
    J Biol Chem; 2016 Jun 10; 291(24):12809-12820. PubMed ID: 27129249
    [Abstract] [Full Text] [Related]

  • 19. Conditional loss of ErbB3 delays mammary gland hyperplasia induced by mutant PIK3CA without affecting mammary tumor latency, gene expression, or signaling.
    Young CD, Pfefferle AD, Owens P, Kuba MG, Rexer BN, Balko JM, Sánchez V, Cheng H, Perou CM, Zhao JJ, Cook RS, Arteaga CL.
    Cancer Res; 2013 Jul 01; 73(13):4075-85. PubMed ID: 23633485
    [Abstract] [Full Text] [Related]

  • 20. Conditional deletion of Shp2 in the mammary gland leads to impaired lobulo-alveolar outgrowth and attenuated Stat5 activation.
    Ke Y, Lesperance J, Zhang EE, Bard-Chapeau EA, Oshima RG, Muller WJ, Feng GS.
    J Biol Chem; 2006 Nov 10; 281(45):34374-80. PubMed ID: 16959766
    [Abstract] [Full Text] [Related]


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