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423 related items for PubMed ID: 24472725
1. mGluR5 antagonist-induced psychoactive properties: MTEP drug discrimination, a pharmacologically selective non-NMDA effect with apparent lack of reinforcing properties. Swedberg MD, Ellgren M, Raboisson P. J Pharmacol Exp Ther; 2014 Apr; 349(1):155-64. PubMed ID: 24472725 [Abstract] [Full Text] [Related]
2. AZD9272 and AZD2066: selective and highly central nervous system penetrant mGluR5 antagonists characterized by their discriminative effects. Swedberg MD, Raboisson P. J Pharmacol Exp Ther; 2014 Aug; 350(2):212-22. PubMed ID: 24876235 [Abstract] [Full Text] [Related]
3. Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors. Lea PM, Movsesyan VA, Faden AI. Br J Pharmacol; 2005 Jun; 145(4):527-34. PubMed ID: 15821750 [Abstract] [Full Text] [Related]
4. The selective mGlu5 receptor antagonist MTEP, similar to NMDA receptor antagonists, induces social isolation in rats. Koros E, Rosenbrock H, Birk G, Weiss C, Sams-Dodd F. Neuropsychopharmacology; 2007 Mar; 32(3):562-76. PubMed ID: 16794564 [Abstract] [Full Text] [Related]
5. A novel mGluR5 antagonist, MFZ 10-7, inhibits cocaine-taking and cocaine-seeking behavior in rats. Keck TM, Zou MF, Bi GH, Zhang HY, Wang XF, Yang HJ, Srivastava R, Gardner EL, Xi ZX, Newman AH. Addict Biol; 2014 Mar; 19(2):195-209. PubMed ID: 24001208 [Abstract] [Full Text] [Related]
6. The antinociceptive and anxiolytic-like effects of the metabotropic glutamate receptor 5 (mGluR5) antagonists, MPEP and MTEP, and the mGluR1 antagonist, LY456236, in rodents: a comparison of efficacy and side-effect profiles. Varty GB, Grilli M, Forlani A, Fredduzzi S, Grzelak ME, Guthrie DH, Hodgson RA, Lu SX, Nicolussi E, Pond AJ, Parker EM, Hunter JC, Higgins GA, Reggiani A, Bertorelli R. Psychopharmacology (Berl); 2005 Apr; 179(1):207-17. PubMed ID: 15682298 [Abstract] [Full Text] [Related]
7. Evaluation of the reinforcing and discriminative stimulus properties of the low-affinity N-methyl-D-aspartate channel blocker memantine. Nicholson KL, Jones HE, Balster RL. Behav Pharmacol; 1998 May; 9(3):231-43. PubMed ID: 9832937 [Abstract] [Full Text] [Related]
8. mGluR5, but not mGluR1, antagonist modifies MK-801-induced locomotor activity and deficit of prepulse inhibition. Pietraszek M, Gravius A, Schäfer D, Weil T, Trifanova D, Danysz W. Neuropharmacology; 2005 Jul; 49(1):73-85. PubMed ID: 15992582 [Abstract] [Full Text] [Related]
9. Dissociation of the effects of MTEP [3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]piperidine] on conditioned reinstatement and reinforcement: comparison between cocaine and a conventional reinforcer. Martin-Fardon R, Baptista MA, Dayas CV, Weiss F. J Pharmacol Exp Ther; 2009 Jun; 329(3):1084-90. PubMed ID: 19258516 [Abstract] [Full Text] [Related]
11. Lowered brain stimulation reward thresholds in rats treated with a combination of caffeine and N-methyl-D-aspartate but not alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate or metabotropic glutamate receptor-5 receptor antagonists. Bespalov A, Dravolina O, Belozertseva I, Adamcio B, Zvartau E. Behav Pharmacol; 2006 Jun; 17(4):295-302. PubMed ID: 16914947 [Abstract] [Full Text] [Related]
12. Dissociable effects of mGluR5 allosteric modulation on distinct forms of impulsivity in rats: interaction with NMDA receptor antagonism. Isherwood SN, Pekcec A, Nicholson JR, Robbins TW, Dalley JW. Psychopharmacology (Berl); 2015 Sep; 232(18):3327-44. PubMed ID: 26063678 [Abstract] [Full Text] [Related]
13. Synthesis and structure-activity relationships of 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine analogues as potent, noncompetitive metabotropic glutamate receptor subtype 5 antagonists; search for cocaine medications. Iso Y, Grajkowska E, Wroblewski JT, Davis J, Goeders NE, Johnson KM, Sanker S, Roth BL, Tueckmantel W, Kozikowski AP. J Med Chem; 2006 Feb 09; 49(3):1080-100. PubMed ID: 16451073 [Abstract] [Full Text] [Related]
14. Transcriptional profiling of the rat frontal cortex following administration of the mGlu5 receptor antagonists MPEP and MTEP. Gass JT, Olive MF. Eur J Pharmacol; 2008 Apr 28; 584(2-3):253-62. PubMed ID: 18346726 [Abstract] [Full Text] [Related]
15. Evaluation of the phencyclidine-like discriminative stimulus effects of novel NMDA channel blockers in rats. Nicholson KL, Balster RL. Psychopharmacology (Berl); 2003 Nov 28; 170(2):215-24. PubMed ID: 12851738 [Abstract] [Full Text] [Related]
16. Characterization of the discriminative stimulus effects of N-methyl- D-aspartate ligands under different ethanol training conditions in the cynomolgus monkey ( Macaca fascicularis). Vivian JA, Waters CA, Szeliga KT, Jordan K, Grant KA. Psychopharmacology (Berl); 2002 Jul 28; 162(3):273-81. PubMed ID: 12122485 [Abstract] [Full Text] [Related]
17. Attenuation of behavioral effects of cocaine by the Metabotropic Glutamate Receptor 5 Antagonist 2-Methyl-6-(phenylethynyl)-pyridine in squirrel monkeys: comparison with dizocilpine. Lee B, Platt DM, Rowlett JK, Adewale AS, Spealman RD. J Pharmacol Exp Ther; 2005 Mar 28; 312(3):1232-40. PubMed ID: 15550570 [Abstract] [Full Text] [Related]
18. mGluR5 antagonists 2-methyl-6-(phenylethynyl)-pyridine and (E)-2-methyl-6-(2-phenylethenyl)-pyridine reduce traumatic neuronal injury in vitro and in vivo by antagonizing N-methyl-D-aspartate receptors. Movsesyan VA, O'Leary DM, Fan L, Bao W, Mullins PG, Knoblach SM, Faden AI. J Pharmacol Exp Ther; 2001 Jan 28; 296(1):41-7. PubMed ID: 11123360 [Abstract] [Full Text] [Related]
19. Potential antidepressant-like effect of MTEP, a potent and highly selective mGluR5 antagonist. Pałucha A, Brański P, Szewczyk B, Wierońska JM, Kłak K, Pilc A. Pharmacol Biochem Behav; 2005 Aug 28; 81(4):901-6. PubMed ID: 16040106 [Abstract] [Full Text] [Related]
20. The behavioral profile of the potent and selective mGlu5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) in rodent models of anxiety. Busse CS, Brodkin J, Tattersall D, Anderson JJ, Warren N, Tehrani L, Bristow LJ, Varney MA, Cosford ND. Neuropsychopharmacology; 2004 Nov 28; 29(11):1971-9. PubMed ID: 15305166 [Abstract] [Full Text] [Related] Page: [Next] [New Search]