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Journal Abstract Search

128 related items for PubMed ID: 2454830

  • 1. Wy-48,252 (1,1,1-trifluoro-N-[3-(2-quinolinylmethoxy)phenyl]membrane sulfonamide), an orally active leukotriene antagonist: effects on arachidonic acid metabolism in various inflammatory cells.
    Chang J, Borgeat P, Schleimer RP, Musser JH, Marshall LA, Hand JM.
    Eur J Pharmacol; 1988 Mar 22; 148(1):131-41. PubMed ID: 2454830
    [Abstract] [Full Text] [Related]

  • 2. Modulation by hydroxyeicosatetraenoic acids (HETEs) of arachidonic acid metabolism in mouse resident peritoneal macrophages.
    Chang J, Lamb B, Marinari L, Kreft AF, Lewis AJ.
    Eur J Pharmacol; 1985 Jan 02; 107(2):215-22. PubMed ID: 3920057
    [Abstract] [Full Text] [Related]

  • 3. Wy-48,252 (1,1,1-trifluoro-N-[3-(2-quinolinylmethoxy)phenyl]methane sulfonamide) an orally active leukotriene D4 antagonist: pharmacological characterization in vitro and in vivo in the guinea pig.
    Hand JM, Schwalm SF, Auen MA, Kreft AF, Musser JH, Chang J.
    Prostaglandins Leukot Essent Fatty Acids; 1989 Aug 02; 37(2):97-106. PubMed ID: 2780767
    [Abstract] [Full Text] [Related]

  • 4. Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models.
    Carty TJ, Sweeney FJ, Griffiths RJ, Eskra JD, Ernest MJ, Pillar JS, Cheng JD, Loose LD, Joseph PA, Pazoles PP, Moore PF, Nagahisa A, Murase S, Kadin SB.
    Inflamm Res; 1997 May 02; 46(5):168-79. PubMed ID: 9197987
    [Abstract] [Full Text] [Related]

  • 5. Effect of a novel leukotriene D4 antagonist with 5-lipoxygenase and cyclooxygenase inhibitory activity, Wy-45,911, on leukotriene-D4-and antigen-induced bronchoconstriction in the guinea pig.
    Chang J, Musser JH, Hand JM.
    Int Arch Allergy Appl Immunol; 1988 May 02; 86(1):48-54. PubMed ID: 2836315
    [Abstract] [Full Text] [Related]

  • 6. Oxidative transformations of arachidonic acid in human dispersed lung cells: disparity between the utilization of endogenous and exogenous substrate.
    Harvey J, Holgate ST, Peters BJ, Robinson C, Walker JR.
    Br J Pharmacol; 1985 Oct 02; 86(2):417-26. PubMed ID: 3931732
    [Abstract] [Full Text] [Related]

  • 7. Generation of leukotriene C4, leukotriene B4, and prostaglandin D2 by immunologically activated rat intestinal mucosa mast cells.
    Heavey DJ, Ernst PB, Stevens RL, Befus AD, Bienenstock J, Austen KF.
    J Immunol; 1988 Mar 15; 140(6):1953-7. PubMed ID: 2450136
    [Abstract] [Full Text] [Related]

  • 8. Ionophore-dependent generation of eicosanoids in human dispersed lung cells. Modulation by 6,9-deepoxy-6,9-(phenylimino)-delta 6,8-prostaglandin I1 (U-60,257).
    Robinson C, Holgate ST.
    Biochem Pharmacol; 1986 Jun 01; 35(11):1903-8. PubMed ID: 3087365
    [Abstract] [Full Text] [Related]

  • 9. Inhibition by methylprednisolone of zymosan-induced leukotriene synthesis in alveolar macrophages.
    Peters-Golden M, Thebert P.
    Am Rev Respir Dis; 1987 May 01; 135(5):1020-6. PubMed ID: 3034108
    [Abstract] [Full Text] [Related]

  • 10. Differential release of eicosanoids by bradykinin, arachidonic acid and calcium ionophore A23187 in guinea-pig isolated perfused lung.
    Bakhle YS, Moncada S, de Nucci G, Salmon JA.
    Br J Pharmacol; 1985 Sep 01; 86(1):55-62. PubMed ID: 2996675
    [Abstract] [Full Text] [Related]

  • 11. Differential effects of monoHETEs (monohydroxyeicosatetraenoic acids) on arachidonic acid metabolism in glycogen-elicited rat polymorphonuclear leukocytes.
    Chang J, Skowronek MD, Lewis AJ.
    Inflammation; 1985 Dec 01; 9(4):395-406. PubMed ID: 3000941
    [Abstract] [Full Text] [Related]

  • 12. Modulation of alveolar macrophage-derived 5-lipoxygenase products by the sulfhydryl reactant, N-ethylmaleimide.
    Peters-Golden M, Shelly C.
    J Biol Chem; 1987 Aug 05; 262(22):10594-600. PubMed ID: 3112148
    [Abstract] [Full Text] [Related]

  • 13. An analysis of the relationship between 5-lipoxygenase product generation and the secretion of preformed mediators from mouse bone marrow-derived mast cells.
    Razin E, Romeo LC, Krilis S, Liu FT, Lewis RA, Corey EJ, Austen KF.
    J Immunol; 1984 Aug 05; 133(2):938-45. PubMed ID: 6330206
    [Abstract] [Full Text] [Related]

  • 14. WY-50,295 tromethamine, a novel, orally active 5-lipoxygenase inhibitor: biochemical characterization and antiallergic activity.
    Grimes D, Sturm RJ, Marinari LR, Carlson RP, Berkenkopf JW, Musser JH, Kreft AF, Weichman BM.
    Eur J Pharmacol; 1993 May 19; 236(2):217-28. PubMed ID: 8391458
    [Abstract] [Full Text] [Related]

  • 15. Studies on the release of leukotrienes and histamine by human lung parenchymal and bronchial fragments upon immunologic and nonimmunologic stimulation. Effects of nordihydroguaiaretic acid, aspirin, and sodium cromoglycate.
    Salari H, Borgeat P, Fournier M, Hebert J, Pelletier G.
    J Exp Med; 1985 Dec 01; 162(6):1904-15. PubMed ID: 2415659
    [Abstract] [Full Text] [Related]

  • 16. Metabolism of arachidonic acid through the 5-lipoxygenase pathway in normal human peritoneal macrophages.
    Laviolette M, Carreau M, Coulombe R, Cloutier D, Dupont P, Rioux J, Braquet P, Borgeat P.
    J Immunol; 1988 Sep 15; 141(6):2104-9. PubMed ID: 2844895
    [Abstract] [Full Text] [Related]

  • 17. Stimulation of arachidonic acid metabolism and generation of thromboxane A2 by leukotrienes B4, C4 and D4 in guinea-pig lung in vitro.
    Piper PJ, Samhoun MN.
    Br J Pharmacol; 1982 Oct 15; 77(2):267-75. PubMed ID: 6291685
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and metabolism of leukotrienes by human endothelial cells: influence on prostacyclin release.
    Ibe BO, Campbell WB.
    Biochim Biophys Acta; 1988 Jun 15; 960(3):309-21. PubMed ID: 2838089
    [Abstract] [Full Text] [Related]

  • 19. SK&F 86002: a structurally novel anti-inflammatory agent that inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid.
    Griswold DE, Marshall PJ, Webb EF, Godfrey R, Newton J, DiMartino MJ, Sarau HM, Gleason JG, Poste G, Hanna N.
    Biochem Pharmacol; 1987 Oct 15; 36(20):3463-70. PubMed ID: 2823821
    [Abstract] [Full Text] [Related]

  • 20. Pharmacology of the pyrroloimidazole, SK&F 105809--I. Inhibition of inflammatory cytokine production and of 5-lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid.
    Marshall PJ, Griswold DE, Breton J, Webb EF, Hillegass LM, Sarau HM, Newton J, Lee JC, Bender PE, Hanna N.
    Biochem Pharmacol; 1991 Jul 25; 42(4):813-24. PubMed ID: 1907824
    [Abstract] [Full Text] [Related]

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