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285 related items for PubMed ID: 24561043
21. The dual kinase inhibitor NVP-BEZ235 in combination with cytotoxic drugs exerts anti-proliferative activity towards acute lymphoblastic leukemia cells. Schult C, Dahlhaus M, Glass A, Fischer K, Lange S, Freund M, Junghanss C. Anticancer Res; 2012 Feb; 32(2):463-74. PubMed ID: 22287733 [Abstract] [Full Text] [Related]
22. Increased activation of PI3K/AKT signaling pathway is associated with cholangiocarcinoma metastasis and PI3K/mTOR inhibition presents a possible therapeutic strategy. Yothaisong S, Dokduang H, Techasen A, Namwat N, Yongvanit P, Bhudhisawasdi V, Puapairoj A, Riggins GJ, Loilome W. Tumour Biol; 2013 Dec; 34(6):3637-48. PubMed ID: 23832540 [Abstract] [Full Text] [Related]
23. Dual PI3K/mTOR inhibitor NVP-BEZ235-induced apoptosis of hepatocellular carcinoma cell lines is enhanced by inhibitors of autophagy. Chang Z, Shi G, Jin J, Guo H, Guo X, Luo F, Song Y, Jia X. Int J Mol Med; 2013 Jun; 31(6):1449-56. PubMed ID: 23588698 [Abstract] [Full Text] [Related]
24. Dual PI3K/mTOR inhibitor NVP-BEZ235 suppresses hypoxia-inducible factor (HIF)-1α expression by blocking protein translation and increases cell death under hypoxia. Karar J, Cerniglia GJ, Lindsten T, Koumenis C, Maity A. Cancer Biol Ther; 2012 Sep; 13(11):1102-11. PubMed ID: 22895065 [Abstract] [Full Text] [Related]
25. Antimyeloma activity of the orally bioavailable dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235. McMillin DW, Ooi M, Delmore J, Negri J, Hayden P, Mitsiades N, Jakubikova J, Maira SM, Garcia-Echeverria C, Schlossman R, Munshi NC, Richardson PG, Anderson KC, Mitsiades CS. Cancer Res; 2009 Jul 15; 69(14):5835-42. PubMed ID: 19584292 [Abstract] [Full Text] [Related]
26. Superior efficacy of co-treatment with dual PI3K/mTOR inhibitor NVP-BEZ235 and pan-histone deacetylase inhibitor against human pancreatic cancer. Venkannagari S, Fiskus W, Peth K, Atadja P, Hidalgo M, Maitra A, Bhalla KN. Oncotarget; 2012 Nov 15; 3(11):1416-27. PubMed ID: 23232026 [Abstract] [Full Text] [Related]
27. Dual inhibitor of phosphoinositide 3-kinase/mammalian target of rapamycin NVP-BEZ235 effectively inhibits cisplatin-resistant urothelial cancer cell growth through autophagic flux. Li JR, Cheng CL, Yang CR, Ou YC, Wu MJ, Ko JL. Toxicol Lett; 2013 Jul 18; 220(3):267-76. PubMed ID: 23651616 [Abstract] [Full Text] [Related]
28. Bufalin suppresses hepatocellular carcinoma invasion and metastasis by targeting HIF-1α via the PI3K/AKT/mTOR pathway. Wang H, Zhang C, Xu L, Zang K, Ning Z, Jiang F, Chi H, Zhu X, Meng Z. Oncotarget; 2016 Apr 12; 7(15):20193-208. PubMed ID: 26958938 [Abstract] [Full Text] [Related]
29. The efficacy of the novel dual PI3-kinase/mTOR inhibitor NVP-BEZ235 compared with rapamycin in renal cell carcinoma. Cho DC, Cohen MB, Panka DJ, Collins M, Ghebremichael M, Atkins MB, Signoretti S, Mier JW. Clin Cancer Res; 2010 Jul 15; 16(14):3628-38. PubMed ID: 20606035 [Abstract] [Full Text] [Related]
30. NVP-BEZ235, a dual pan class I PI3 kinase and mTOR inhibitor, promotes osteogenic differentiation in human mesenchymal stromal cells. Martin SK, Fitter S, Bong LF, Drew JJ, Gronthos S, Shepherd PR, Zannettino AC. J Bone Miner Res; 2010 Oct 15; 25(10):2126-37. PubMed ID: 20499346 [Abstract] [Full Text] [Related]
31. Inhibition of autophagy as a strategy to augment radiosensitization by the dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235. Cerniglia GJ, Karar J, Tyagi S, Christofidou-Solomidou M, Rengan R, Koumenis C, Maity A. Mol Pharmacol; 2012 Dec 15; 82(6):1230-40. PubMed ID: 22989521 [Abstract] [Full Text] [Related]
32. Dual inhibition of PI3K and mTORC1/2 signaling by NVP-BEZ235 as a new therapeutic strategy for acute myeloid leukemia. Chapuis N, Tamburini J, Green AS, Vignon C, Bardet V, Neyret A, Pannetier M, Willems L, Park S, Macone A, Maira SM, Ifrah N, Dreyfus F, Herault O, Lacombe C, Mayeux P, Bouscary D. Clin Cancer Res; 2010 Nov 15; 16(22):5424-35. PubMed ID: 20884625 [Abstract] [Full Text] [Related]
33. NVP-BEZ235, a dual PI3K/mTOR inhibitor, induces cell death through alternate routes in prostate cancer cells depending on the PTEN genotype. Hong SW, Shin JS, Moon JH, Kim YS, Lee J, Choi EK, Ha SH, Lee DH, Chung HN, Kim JE, Kim KP, Hong YS, Lee JL, Lee WJ, Choi EK, Lee JS, Jin DH, Kim TW. Apoptosis; 2014 May 15; 19(5):895-904. PubMed ID: 24652480 [Abstract] [Full Text] [Related]
34. NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomas. Liu TJ, Koul D, LaFortune T, Tiao N, Shen RJ, Maira SM, Garcia-Echevrria C, Yung WK. Mol Cancer Ther; 2009 Aug 15; 8(8):2204-10. PubMed ID: 19671762 [Abstract] [Full Text] [Related]