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Journal Abstract Search

342 related items for PubMed ID: 24562907

  • 1. Genetic validation of aminoacyl-tRNA synthetases as drug targets in Trypanosoma brucei.
    Kalidas S, Cestari I, Monnerat S, Li Q, Regmi S, Hasle N, Labaied M, Parsons M, Stuart K, Phillips MA.
    Eukaryot Cell; 2014 Apr; 13(4):504-16. PubMed ID: 24562907
    [Abstract] [Full Text] [Related]

  • 2. Genetic manipulation of Leishmania donovani threonyl tRNA synthetase facilitates its exploration as a potential therapeutic target.
    Chadha S, Vijayan R, Gupta S, Munde M, Gourinath S, Madhubala R.
    PLoS Negl Trop Dis; 2018 Jun; 12(6):e0006575. PubMed ID: 29897900
    [Abstract] [Full Text] [Related]

  • 3. Non-canonical eukaryotic glutaminyl- and glutamyl-tRNA synthetases form mitochondrial aminoacyl-tRNA in Trypanosoma brucei.
    Rinehart J, Horn EK, Wei D, Soll D, Schneider A.
    J Biol Chem; 2004 Jan 09; 279(2):1161-6. PubMed ID: 14563839
    [Abstract] [Full Text] [Related]

  • 4. Aminoacyl tRNA synthetases as malarial drug targets: a comparative bioinformatics study.
    Nyamai DW, Tastan Bishop Ö.
    Malar J; 2019 Feb 06; 18(1):34. PubMed ID: 30728021
    [Abstract] [Full Text] [Related]

  • 5. Aminoacyl-tRNA Synthetases: On Anti-Synthetase Syndrome and Beyond.
    Galindo-Feria AS, Notarnicola A, Lundberg IE, Horuluoglu B.
    Front Immunol; 2022 Feb 06; 13():866087. PubMed ID: 35634293
    [Abstract] [Full Text] [Related]

  • 6. Selective inhibitors of methionyl-tRNA synthetase have potent activity against Trypanosoma brucei Infection in Mice.
    Shibata S, Gillespie JR, Kelley AM, Napuli AJ, Zhang Z, Kovzun KV, Pefley RM, Lam J, Zucker FH, Van Voorhis WC, Merritt EA, Hol WG, Verlinde CL, Fan E, Buckner FS.
    Antimicrob Agents Chemother; 2011 May 06; 55(5):1982-9. PubMed ID: 21282428
    [Abstract] [Full Text] [Related]

  • 7. A multiple aminoacyl-tRNA synthetase complex that enhances tRNA-aminoacylation in African trypanosomes.
    Cestari I, Kalidas S, Monnerat S, Anupama A, Phillips MA, Stuart K.
    Mol Cell Biol; 2013 Dec 06; 33(24):4872-88. PubMed ID: 24126051
    [Abstract] [Full Text] [Related]

  • 8. Structural analyses of the malaria parasite aminoacyl-tRNA synthetases provide new avenues for antimalarial drug discovery.
    Chhibber-Goel J, Yogavel M, Sharma A.
    Protein Sci; 2021 Sep 06; 30(9):1793-1803. PubMed ID: 34184352
    [Abstract] [Full Text] [Related]

  • 9. Escherichia coli mutants overproducing phenylalanyl- and threonyl-tRNA synthetase.
    Grüll JM, Hennecke H, Fröhler J, Thomale J, Nass G, Böck A.
    J Bacteriol; 1979 Jan 06; 137(1):480-9. PubMed ID: 368026
    [Abstract] [Full Text] [Related]

  • 10. Characterization of Aminoacyl-tRNA Synthetases in Chromerids.
    Sharaf A, Gruber A, Jiroutová K, Oborník M.
    Genes (Basel); 2019 Jul 31; 10(8):. PubMed ID: 31370303
    [Abstract] [Full Text] [Related]

  • 11. [Cloning, expression, purification and activity assay of Trypanosoma brucei phenylalanyl-tRNA synthetase in Escherichia coli].
    Yao Y, Gao G, Li D.
    Sheng Wu Gong Cheng Xue Bao; 2010 Jan 31; 26(1):130-5. PubMed ID: 20353103
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of isoleucyl-tRNA synthetase as a potential treatment for human African Trypanosomiasis.
    Cestari I, Stuart K.
    J Biol Chem; 2013 May 17; 288(20):14256-14263. PubMed ID: 23548908
    [Abstract] [Full Text] [Related]

  • 13. Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase.
    Merritt EA, Arakaki TL, Gillespie R, Napuli AJ, Kim JE, Buckner FS, Van Voorhis WC, Verlinde CL, Fan E, Zucker F, Hol WG.
    Mol Biochem Parasitol; 2011 May 17; 177(1):20-8. PubMed ID: 21255615
    [Abstract] [Full Text] [Related]

  • 14. Dual targeting of a single tRNA(Trp) requires two different tryptophanyl-tRNA synthetases in Trypanosoma brucei.
    Charrière F, Helgadóttir S, Horn EK, Söll D, Schneider A.
    Proc Natl Acad Sci U S A; 2006 May 02; 103(18):6847-52. PubMed ID: 16636268
    [Abstract] [Full Text] [Related]

  • 15. Dual targeting of aminoacyl-tRNA synthetases to the apicoplast and cytosol in Plasmodium falciparum.
    Jackson KE, Pham JS, Kwek M, De Silva NS, Allen SM, Goodman CD, McFadden GI, Ribas de Pouplana L, Ralph SA.
    Int J Parasitol; 2012 Feb 02; 42(2):177-86. PubMed ID: 22222968
    [Abstract] [Full Text] [Related]

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  • 17. Deoxyhypusine Modification of Eukaryotic Translation Initiation Factor 5A (eIF5A) Is Essential for Trypanosoma brucei Growth and for Expression of Polyprolyl-containing Proteins.
    Nguyen S, Leija C, Kinch L, Regmi S, Li Q, Grishin NV, Phillips MA.
    J Biol Chem; 2015 Aug 07; 290(32):19987-98. PubMed ID: 26082486
    [Abstract] [Full Text] [Related]

  • 18. Role of aminoacyl-tRNA synthetases in infectious diseases and targets for therapeutic development.
    Dewan V, Reader J, Forsyth KM.
    Top Curr Chem; 2014 Aug 07; 344():293-329. PubMed ID: 23666077
    [Abstract] [Full Text] [Related]

  • 19. Targeting tRNA-synthetase interactions towards novel therapeutic discovery against eukaryotic pathogens.
    Kelly P, Hadi-Nezhad F, Liu DY, Lawrence TJ, Linington RG, Ibba M, Ardell DH.
    PLoS Negl Trop Dis; 2020 Feb 07; 14(2):e0007983. PubMed ID: 32106219
    [Abstract] [Full Text] [Related]

  • 20. Mechanism of the activation step of the aminoacylation reaction: a significant difference between class I and class II synthetases.
    Banik SD, Nandi N.
    J Biomol Struct Dyn; 2012 Feb 07; 30(6):701-15. PubMed ID: 22731388
    [Abstract] [Full Text] [Related]

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