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441 related items for PubMed ID: 24566615

  • 1. Immunosuppressive agent leflunomide: a SWNTs-immobilized dihydroortate dehydrogenase inhibitory effect and computational study of its adsorption properties on zigzag single walled (6,0) carbon and boron nitride nanotubes as controlled drug delivery devices.
    Raissi H, Mollania F.
    Eur J Pharm Sci; 2014 Jun 02; 56():37-54. PubMed ID: 24566615
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of dihydroorotate dehydrogenase by the immunosuppressive agent leflunomide.
    Greene S, Watanabe K, Braatz-Trulson J, Lou L.
    Biochem Pharmacol; 1995 Sep 07; 50(6):861-7. PubMed ID: 7575649
    [Abstract] [Full Text] [Related]

  • 3. Effect of the Intramolecular Hydrogen Bond on the Active Metabolite Analogs of Leflunomide for Blocking the Plasmodium falciparum Dihydroorotate Dehydrogenase Enzyme: QTAIM, NBO, and Docking Study.
    Heidarian R, Zahedi-Tabrizi M.
    Curr Comput Aided Drug Des; 2021 Sep 07; 17(3):480-491. PubMed ID: 32459610
    [Abstract] [Full Text] [Related]

  • 4. Theoretical study of addition reactions of heavy carbenes to carbon and boron nitride nanotubes.
    Su MD.
    J Phys Chem B; 2005 Nov 24; 109(46):21647-57. PubMed ID: 16853811
    [Abstract] [Full Text] [Related]

  • 5. Dihydroorotate dehydrogenase inhibitor A771726 (leflunomide) induces apoptosis and diminishes proliferation of multiple myeloma cells.
    Baumann P, Mandl-Weber S, Völkl A, Adam C, Bumeder I, Oduncu F, Schmidmaier R.
    Mol Cancer Ther; 2009 Feb 24; 8(2):366-75. PubMed ID: 19174558
    [Abstract] [Full Text] [Related]

  • 6. The immunosuppressive metabolite of leflunomide is a potent inhibitor of human dihydroorotate dehydrogenase.
    Davis JP, Cain GA, Pitts WJ, Magolda RL, Copeland RA.
    Biochemistry; 1996 Jan 30; 35(4):1270-3. PubMed ID: 8573583
    [Abstract] [Full Text] [Related]

  • 7. Comparative prediction of binding affinity of Hydroxyurea anti-cancer to boron nitride and carbon nanotubes as smart targeted drug delivery vehicles.
    Mortazavifar A, Raissi H, Shahabi M.
    J Biomol Struct Dyn; 2019 Nov 30; 37(18):4852-4862. PubMed ID: 30721644
    [Abstract] [Full Text] [Related]

  • 8. Species-related inhibition of human and rat dihydroorotate dehydrogenase by immunosuppressive isoxazol and cinchoninic acid derivatives.
    Knecht W, Löffler M.
    Biochem Pharmacol; 1998 Nov 01; 56(9):1259-64. PubMed ID: 9802339
    [Abstract] [Full Text] [Related]

  • 9. The effect of exon (19C>A) dihydroorotate dehydrogenase gene polymorphism on rheumatoid arthritis treatment with leflunomide.
    Pawlik A, Herczynska M, Kurzawski M, Safranow K, Dziedziejko V, Drozdzik M.
    Pharmacogenomics; 2009 Feb 01; 10(2):303-9. PubMed ID: 19207032
    [Abstract] [Full Text] [Related]

  • 10. Effect of substitutionally boron-doped single-walled semiconducting zigzag carbon nanotubes on ammonia adsorption.
    Vikramaditya T, Sumithra K.
    J Comput Chem; 2014 Mar 15; 35(7):586-94. PubMed ID: 24395720
    [Abstract] [Full Text] [Related]

  • 11. The immunosuppressant leflunomide inhibits lymphocyte proliferation by inhibiting pyrimidine biosynthesis.
    Cherwinski HM, Cohn RG, Cheung P, Webster DJ, Xu YZ, Caulfield JP, Young JM, Nakano G, Ransom JT.
    J Pharmacol Exp Ther; 1995 Nov 15; 275(2):1043-9. PubMed ID: 7473131
    [Abstract] [Full Text] [Related]

  • 12. Human dihydroorotate dehydrogenase inhibitors, a novel approach for the treatment of autoimmune and inflammatory diseases.
    Leban J, Vitt D.
    Arzneimittelforschung; 2011 Nov 15; 61(1):66-72. PubMed ID: 21355448
    [Abstract] [Full Text] [Related]

  • 13. 3D-QSAR studies on a series of dihydroorotate dehydrogenase inhibitors: analogues of the active metabolite of leflunomide.
    Li SL, He MY, Du HG.
    Int J Mol Sci; 2011 Nov 15; 12(5):2982-93. PubMed ID: 21686163
    [Abstract] [Full Text] [Related]

  • 14. Cryogenic separation of hydrogen isotopes in single-walled carbon and boron-nitride nanotubes: insight into the mechanism of equilibrium quantum sieving in quasi-one-dimensional pores.
    Kowalczyk P, Gauden PA, Terzyk AP.
    J Phys Chem B; 2008 Jul 17; 112(28):8275-84. PubMed ID: 18570395
    [Abstract] [Full Text] [Related]

  • 15. Chemical reactivity and adsorption properties of pro-carbazine anti-cancer drug on gallium-doped nanotubes: a quantum chemical study.
    Ghoreishi R, Kia M.
    J Mol Model; 2019 Jan 28; 25(2):46. PubMed ID: 30689092
    [Abstract] [Full Text] [Related]

  • 16. Inhibiting the teratogenicity of the immunosuppressant leflunomide in mice by supplementation of exogenous uridine.
    Fukushima R, Kanamori S, Hirashiba M, Hishikawa A, Muranaka R, Kaneto M, Kitagawa H.
    Toxicol Sci; 2009 Apr 28; 108(2):419-26. PubMed ID: 19190124
    [Abstract] [Full Text] [Related]

  • 17. Precision Medicine With Leflunomide: Consideration of the DHODH Haplotype and Plasma Teriflunomide Concentration and Modification of Outcomes in Patients With Rheumatoid Arthritis.
    Wiese MD, Hopkins AM, King C, Wechalekar MD, Lee A, Spargo L, Metcalf R, McWilliams L, Hill C, Cleland LG, Proudman SM.
    Arthritis Care Res (Hoboken); 2021 Jul 28; 73(7):983-989. PubMed ID: 32339392
    [Abstract] [Full Text] [Related]

  • 18. Synthesis of beta-hydroxy-propenamide derivatives and the inhibition of human dihydroorotate dehydrogenase.
    Kim TH, Na HS, Löffler M.
    Arch Pharm Res; 2003 Mar 28; 26(3):197-201. PubMed ID: 12723931
    [Abstract] [Full Text] [Related]

  • 19. Non-covalent surface modification of boron nitride nanotubes for enhanced catalysis.
    Li R, Liu J, Li L, Wang H, Weng Z, Lam SK, Du A, Chen Y, Barrow CJ, Yang W.
    Chem Commun (Camb); 2014 Jan 07; 50(2):225-7. PubMed ID: 24225669
    [Abstract] [Full Text] [Related]

  • 20. Conformational stability, spectroscopic and computational studies, hikes' occupied molecular orbital, lowest unoccupied molecular orbital, natural bond orbital analysis and thermodynamic parameters of anticancer drug on nanotube-A review.
    Ghasemi AS, Mashhadban F, Hoseini-Alfatemi SM, Sharifi-Rad J.
    Cell Mol Biol (Noisy-le-grand); 2015 Dec 24; 61(8):74-8. PubMed ID: 26718433
    [Abstract] [Full Text] [Related]

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