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132 related items for PubMed ID: 24568863

  • 1. Energy cost for the proper ionization of active site residues in 6-phosphogluconate dehydrogenase from T. brucei.
    Hanau S, Proietti d'Empaire L, Montin K, Cervellati C, Capone I, Dallocchio F.
    Biochim Biophys Acta; 2014 Apr; 1844(4):785-92. PubMed ID: 24568863
    [Abstract] [Full Text] [Related]

  • 2. Thermodynamic characterization of substrate and inhibitor binding to Trypanosoma brucei 6-phosphogluconate dehydrogenase.
    Montin K, Cervellati C, Dallocchio F, Hanau S.
    FEBS J; 2007 Dec; 274(24):6426-35. PubMed ID: 18021252
    [Abstract] [Full Text] [Related]

  • 3. The 6-phosphogluconate dehydrogenase from Trypanosoma cruzi: the absence of two inter-subunit salt bridges as a reason for enzyme instability.
    Esteve MI, Cazzulo JJ.
    Mol Biochem Parasitol; 2004 Feb; 133(2):197-207. PubMed ID: 14698432
    [Abstract] [Full Text] [Related]

  • 4. A 2.8 A resolution structure of 6-phosphogluconate dehydrogenase from the protozoan parasite Trypanosoma brucei: comparison with the sheep enzyme accounts for differences in activity with coenzyme and substrate analogues.
    Phillips C, Dohnalek J, Gover S, Barrett MP, Adams MJ.
    J Mol Biol; 1998 Sep 25; 282(3):667-81. PubMed ID: 9737929
    [Abstract] [Full Text] [Related]

  • 5. Lysine 183 is the general base in the 6-phosphogluconate dehydrogenase-catalyzed reaction.
    Zhang L, Chooback L, Cook PF.
    Biochemistry; 1999 Aug 31; 38(35):11231-8. PubMed ID: 10471272
    [Abstract] [Full Text] [Related]

  • 6. The effect of specific proline residues on the kinetic stability of the triosephosphate isomerases of two trypanosomes.
    Guzmán-Luna V, Quezada AG, Díaz-Salazar AJ, Cabrera N, Pérez-Montfort R, Costas M.
    Proteins; 2017 Apr 31; 85(4):571-579. PubMed ID: 28002620
    [Abstract] [Full Text] [Related]

  • 7. Site-directed mutagenesis of the active site glutamate in human matrilysin: investigation of its role in catalysis.
    Cha J, Auld DS.
    Biochemistry; 1997 Dec 16; 36(50):16019-24. PubMed ID: 9398337
    [Abstract] [Full Text] [Related]

  • 8. Preliminary crystallographic study of 6-phosphogluconate dehydrogenase from Trypanosoma brucei.
    Phillips C, Barrett MP, Gover S, Le Page RW, Adams MJ.
    J Mol Biol; 1993 Sep 20; 233(2):317-21. PubMed ID: 8377207
    [Abstract] [Full Text] [Related]

  • 9. 6-Phosphogluconate dehydrogenase from Trypanosoma brucei. Kinetic analysis and inhibition by trypanocidal drugs.
    Hanau S, Rippa M, Bertelli M, Dallocchio F, Barrett MP.
    Eur J Biochem; 1996 Sep 15; 240(3):592-9. PubMed ID: 8856059
    [Abstract] [Full Text] [Related]

  • 10. Evidence for dimer/tetramer equilibrium in Trypanosoma brucei 6-phosphogluconate dehydrogenase.
    Hanau S, d'Empaire LP, Capone I, Alberighi S, Montioli R, Dallocchio F.
    Biochim Biophys Acta; 2013 Dec 15; 1834(12):2647-52. PubMed ID: 24096100
    [Abstract] [Full Text] [Related]

  • 11. Kinetic and chemical mechanisms of the sheep liver 6-phosphogluconate dehydrogenase.
    Price NE, Cook PF.
    Arch Biochem Biophys; 1996 Dec 15; 336(2):215-23. PubMed ID: 8954568
    [Abstract] [Full Text] [Related]

  • 12. Effects of buried charged groups on cysteine thiol ionization and reactivity in Escherichia coli thioredoxin: structural and functional characterization of mutants of Asp 26 and Lys 57.
    Dyson HJ, Jeng MF, Tennant LL, Slaby I, Lindell M, Cui DS, Kuprin S, Holmgren A.
    Biochemistry; 1997 Mar 04; 36(9):2622-36. PubMed ID: 9054569
    [Abstract] [Full Text] [Related]

  • 13. Redox properties of human medium-chain acyl-CoA dehydrogenase, modulation by charged active-site amino acid residues.
    Mancini-Samuelson GJ, Kieweg V, Sabaj KM, Ghisla S, Stankovich MT.
    Biochemistry; 1998 Oct 13; 37(41):14605-12. PubMed ID: 9772189
    [Abstract] [Full Text] [Related]

  • 14. Role of the S128, H186, and N187 triad in substrate binding and decarboxylation in the sheep liver 6-phosphogluconate dehydrogenase reaction.
    Li L, Zhang L, Cook PF.
    Biochemistry; 2006 Oct 24; 45(42):12680-6. PubMed ID: 17042485
    [Abstract] [Full Text] [Related]

  • 15. Crystal structures of a bacterial 6-phosphogluconate dehydrogenase reveal aspects of specificity, mechanism and mode of inhibition by analogues of high-energy reaction intermediates.
    Sundaramoorthy R, Iulek J, Barrett MP, Bidet O, Ruda GF, Gilbert IH, Hunter WN.
    FEBS J; 2007 Jan 24; 274(1):275-86. PubMed ID: 17222187
    [Abstract] [Full Text] [Related]

  • 16. Virtual fragment screening for novel inhibitors of 6-phosphogluconate dehydrogenase.
    Ruda GF, Campbell G, Alibu VP, Barrett MP, Brenk R, Gilbert IH.
    Bioorg Med Chem; 2010 Jul 15; 18(14):5056-62. PubMed ID: 20598892
    [Abstract] [Full Text] [Related]

  • 17. The cross-linking by o-phthalaldehyde of two amino acid residues at the active site of 6-phosphogluconate dehydrogenase.
    Giovannini PP, Rippa M, Dallocchio F, Tetaud M, Barrett MP, Hanau S.
    Biochem Mol Biol Int; 1997 Sep 15; 43(1):153-60. PubMed ID: 9315293
    [Abstract] [Full Text] [Related]

  • 18. 6-Phosphogluconate dehydrogenase: the mechanism of action investigated by a comparison of the enzyme from different species.
    Rippa M, Giovannini PP, Barrett MP, Dallocchio F, Hanau S.
    Biochim Biophys Acta; 1998 Dec 08; 1429(1):83-92. PubMed ID: 9920387
    [Abstract] [Full Text] [Related]

  • 19. Selective inhibition of Trypanosoma brucei 6-phosphogluconate dehydrogenase by high-energy intermediate and transition-state analogues.
    Dardonville C, Rinaldi E, Barrett MP, Brun R, Gilbert IH, Hanau S.
    J Med Chem; 2004 Jun 17; 47(13):3427-37. PubMed ID: 15189039
    [Abstract] [Full Text] [Related]

  • 20. Selective inhibition of 6-phosphogluconate dehydrogenase from Trypanosoma brucei.
    Bertelli M, El-Bastawissy E, Knaggs MH, Barrett MP, Hanau S, Gilbert IH.
    J Comput Aided Mol Des; 2001 May 17; 15(5):465-75. PubMed ID: 11394739
    [Abstract] [Full Text] [Related]

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