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Journal Abstract Search

95 related items for PubMed ID: 24576065

  • 1. Over-expression of PRAS40 enhances insulin sensitivity in skeletal muscle.
    Wiza C, Chadt A, Blumensatt M, Kanzleiter T, Herzfeld De Wiza D, Horrighs A, Mueller H, Nascimento EB, Schürmann A, Al-Hasani H, Ouwens DM.
    Arch Physiol Biochem; 2014 May; 120(2):64-72. PubMed ID: 24576065
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  • 2. Knockdown of PRAS40 inhibits insulin action via proteasome-mediated degradation of IRS1 in primary human skeletal muscle cells.
    Wiza C, Herzfeld de Wiza D, Nascimento EB, Lehr S, Al-Hasani H, Ouwens DM.
    Diabetologia; 2013 May; 56(5):1118-28. PubMed ID: 23460019
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  • 3. Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1.
    Nascimento EB, Snel M, Guigas B, van der Zon GC, Kriek J, Maassen JA, Jazet IM, Diamant M, Ouwens DM.
    Cell Signal; 2010 Jun; 22(6):961-7. PubMed ID: 20138985
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  • 4. Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40.
    Vander Haar E, Lee SI, Bandhakavi S, Griffin TJ, Kim DH.
    Nat Cell Biol; 2007 Mar; 9(3):316-23. PubMed ID: 17277771
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  • 8. Proline-rich Akt substrate of 40-kDa contains a nuclear export signal.
    Wiza C, Nascimento EB, Linssen MM, Carlotti F, Herzfeld de Wiza D, van der Zon GC, Maassen JA, Diamant M, Guigas B, Ouwens DM.
    Cell Signal; 2013 Sep; 25(9):1762-8. PubMed ID: 23712034
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  • 9. The mechanism of insulin-stimulated 4E-BP protein binding to mammalian target of rapamycin (mTOR) complex 1 and its contribution to mTOR complex 1 signaling.
    Rapley J, Oshiro N, Ortiz-Vega S, Avruch J.
    J Biol Chem; 2011 Nov 04; 286(44):38043-38053. PubMed ID: 21914810
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  • 10. Ursolic acid stimulates mTORC1 signaling after resistance exercise in rat skeletal muscle.
    Ogasawara R, Sato K, Higashida K, Nakazato K, Fujita S.
    Am J Physiol Endocrinol Metab; 2013 Sep 15; 305(6):E760-5. PubMed ID: 23900420
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  • 11. Proline-rich AKT substrate of 40-kDa (PRAS40) in the pathophysiology of cancer.
    Malla R, Ashby CR, Narayanan NK, Narayanan B, Faridi JS, Tiwari AK.
    Biochem Biophys Res Commun; 2015 Jul 31; 463(3):161-6. PubMed ID: 26003731
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  • 12. Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation.
    Wang L, Harris TE, Lawrence JC.
    J Biol Chem; 2008 Jun 06; 283(23):15619-27. PubMed ID: 18372248
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  • 13. Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism.
    Guridi M, Kupr B, Romanino K, Lin S, Falcetta D, Tintignac L, Rüegg MA.
    Skelet Muscle; 2016 Jun 06; 6():13. PubMed ID: 27004103
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  • 15. Pathological hypertrophy amelioration by PRAS40-mediated inhibition of mTORC1.
    Völkers M, Toko H, Doroudgar S, Din S, Quijada P, Joyo AY, Ornelas L, Joyo E, Thuerauf DJ, Konstandin MH, Gude N, Glembotski CC, Sussman MA.
    Proc Natl Acad Sci U S A; 2013 Jul 30; 110(31):12661-6. PubMed ID: 23842089
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  • 16. Insulin-mediated phosphorylation of the proline-rich Akt substrate PRAS40 is impaired in insulin target tissues of high-fat diet-fed rats.
    Nascimento EB, Fodor M, van der Zon GC, Jazet IM, Meinders AE, Voshol PJ, Vlasblom R, Baan B, Eckel J, Maassen JA, Diamant M, Ouwens DM.
    Diabetes; 2006 Dec 30; 55(12):3221-8. PubMed ID: 17130464
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  • 17. Regulation of Akt-mTOR, ubiquitin-proteasome and autophagy-lysosome pathways in response to formoterol administration in rat skeletal muscle.
    Joassard OR, Amirouche A, Gallot YS, Desgeorges MM, Castells J, Durieux AC, Berthon P, Freyssenet DG.
    Int J Biochem Cell Biol; 2013 Nov 30; 45(11):2444-55. PubMed ID: 23916784
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  • 18. The binding of PRAS40 to 14-3-3 proteins is not required for activation of mTORC1 signalling by phorbol esters/ERK.
    Fonseca BD, Lee VH, Proud CG.
    Biochem J; 2008 Apr 01; 411(1):141-9. PubMed ID: 18215133
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  • 19. Akt and Rac1 signaling are jointly required for insulin-stimulated glucose uptake in skeletal muscle and downregulated in insulin resistance.
    Sylow L, Kleinert M, Pehmøller C, Prats C, Chiu TT, Klip A, Richter EA, Jensen TE.
    Cell Signal; 2014 Feb 01; 26(2):323-31. PubMed ID: 24216610
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  • 20. TGFβ acts through PDGFRβ to activate mTORC1 via the Akt/PRAS40 axis and causes glomerular mesangial cell hypertrophy and matrix protein expression.
    Maity S, Das F, Kasinath BS, Ghosh-Choudhury N, Ghosh Choudhury G.
    J Biol Chem; 2020 Oct 16; 295(42):14262-14278. PubMed ID: 32732288
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