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103 related items for PubMed ID: 24591318

  • 1. Design, synthesis, lipophilic properties, and binding affinities of potential ligands in positron emission tomography (PET) for visualization of brain dopamine D4 receptors.
    Lacivita E, De Giorgio P, Colabufo NA, Berardi F, Perrone R, Niso M, Leopoldo M.
    Chem Biodivers; 2014 Feb; 11(2):299-310. PubMed ID: 24591318
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis, and binding affinities of potential positron emission tomography (PET) ligands for visualization of brain dopamine D3 receptors.
    Leopoldo M, Lacivita E, De Giorgio P, Colabufo NA, Niso M, Berardi F, Perrone R.
    J Med Chem; 2006 Jan 12; 49(1):358-65. PubMed ID: 16392820
    [Abstract] [Full Text] [Related]

  • 3. In vitro and in vivo evaluation of N-{2-[4-(3-Cyanopyridin-2-yl)piperazin-1-yl]ethyl}-3-[(11) C]methoxybenz-amide, a positron emission tomography (PET) radioligand for dopamine D4 receptors, in rodents.
    Leopoldo M, Selivanova SV, Müller A, Lacivita E, Schetz JA, Ametamey SM.
    Chem Biodivers; 2014 Sep 12; 11(9):1298-308. PubMed ID: 25238073
    [Abstract] [Full Text] [Related]

  • 4. N-[2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide: a potent and selective dopamine D4 ligand.
    Perrone R, Berardi F, Colabufo NA, Leopoldo M, Tortorella V.
    J Med Chem; 1998 Nov 19; 41(24):4903-9. PubMed ID: 9822559
    [Abstract] [Full Text] [Related]

  • 5. Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor.
    Grundt P, Carlson EE, Cao J, Bennett CJ, McElveen E, Taylor M, Luedtke RR, Newman AH.
    J Med Chem; 2005 Feb 10; 48(3):839-48. PubMed ID: 15689168
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis, radiolabeling, and in vivo evaluation of carbon-11 labeled N-[2-[4-(3-cyanopyridin-2-yl)piperazin-1-yl]ethyl]-3-methoxybenzamide, a potential positron emission tomography tracer for the dopamine D(4) receptors.
    Lacivita E, De Giorgio P, Lee IT, Rodeheaver SI, Weiss BA, Fracasso C, Caccia S, Berardi F, Perrone R, Zhang MR, Maeda J, Higuchi M, Suhara T, Schetz JA, Leopoldo M.
    J Med Chem; 2010 Oct 28; 53(20):7344-55. PubMed ID: 20873719
    [Abstract] [Full Text] [Related]

  • 7. Evaluation of 18F-labeled benzodioxine piperazine-based dopamine D4 receptor ligands: lipophilicity as a determinate of nonspecific binding.
    Kügler F, Sihver W, Ermert J, Hübner H, Gmeiner P, Prante O, Coenen HH.
    J Med Chem; 2011 Dec 22; 54(24):8343-52. PubMed ID: 22039961
    [Abstract] [Full Text] [Related]

  • 8. Syntheses and pharmacological evaluation of two potent antagonists for dopamine D4 receptors: [11C]YM-50001 and N-[2-[4-(4-Chlorophenyl)-piperizin-1-yl]ethyl]-3-[11C]methoxybenzamide.
    Zhang MR, Haradahira T, Maeda J, Okauchi T, Kawabe K, Noguchi J, Kida T, Suzuki K, Suhara T.
    Nucl Med Biol; 2002 Feb 22; 29(2):233-41. PubMed ID: 11823129
    [Abstract] [Full Text] [Related]

  • 9. Click chemistry based synthesis of dopamine D4 selective receptor ligands for the selection of potential PET tracers.
    Banerjee A, Maschauer S, Hübner H, Gmeiner P, Prante O.
    Bioorg Med Chem Lett; 2013 Nov 15; 23(22):6079-82. PubMed ID: 24100078
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis, and binding affinities of potential positron emission tomography (PET) ligands with optimal lipophilicity for brain imaging of the dopamine D3 receptor. Part II.
    Leopoldo M, Lacivita E, De Giorgio P, Contino M, Berardi F, Perrone R.
    Bioorg Med Chem; 2009 Jan 15; 17(2):758-66. PubMed ID: 19081257
    [Abstract] [Full Text] [Related]

  • 11. Dopamine D3 and D4 receptor antagonists: synthesis and structure--activity relationships of (S)-(+)-N-(1-Benzyl-3-pyrrolidinyl)-5-chloro-4- [(cyclopropylcarbonyl) amino]-2-methoxybenzamide (YM-43611) and related compounds.
    Ohmori J, Maeno K, Hidaka K, Nakato K, Matsumoto M, Tada S, Hattori H, Sakamoto S, Tsukamoto S, Usuda S, Mase T.
    J Med Chem; 1996 Jul 05; 39(14):2764-72. PubMed ID: 8709107
    [Abstract] [Full Text] [Related]

  • 12. Structure-selectivity investigations of D2-like receptor ligands by CoMFA and CoMSIA guiding the discovery of D3 selective PET radioligands.
    Salama I, Hocke C, Utz W, Prante O, Boeckler F, Hübner H, Kuwert T, Gmeiner P.
    J Med Chem; 2007 Feb 08; 50(3):489-500. PubMed ID: 17266201
    [Abstract] [Full Text] [Related]

  • 13. Labeling of benzodioxin piperazines with fluorine-18 as prospective radioligands for selective imaging of dopamine D4 receptors.
    Kügler F, Ermert J, Coenen HH.
    J Labelled Comp Radiopharm; 2013 Oct 08; 56(12):609-18. PubMed ID: 24285237
    [Abstract] [Full Text] [Related]

  • 14. Structure-affinity relationship study on N-[4-(4-arylpiperazin-1-yl)butyl]arylcarboxamides as potent and selective dopamine D(3) receptor ligands.
    Leopoldo M, Berardi F, Colabufo NA, De Giorgio P, Lacivita E, Perrone R, Tortorella V.
    J Med Chem; 2002 Dec 19; 45(26):5727-35. PubMed ID: 12477356
    [Abstract] [Full Text] [Related]

  • 15. Carbon-11 pb-12: an attempt to visualize the dopamine d(4) receptor in the primate brain with positron emission tomography.
    Langer O, Halldin C, Chou Y, Sandell J, Swahn C, Någren K, Perrone R, Berardi F, Leopoldo M, Farde L.
    Nucl Med Biol; 2000 Nov 19; 27(8):707-14. PubMed ID: 11150701
    [Abstract] [Full Text] [Related]

  • 16.
    Leung K.
    ; 2004 Nov 19. PubMed ID: 23785734
    [Abstract] [Full Text] [Related]

  • 17. S 18126 ([2-[4-(2,3-dihydrobenzo[1,4]dioxin-6-yl)piperazin-1-yl methyl]indan-2-yl]), a potent, selective and competitive antagonist at dopamine D4 receptors: an in vitro and in vivo comparison with L 745,870 (3-(4-[4-chlorophenyl]piperazin-1-yl)methyl-1H-pyrrolo[2, 3b]pyridine) and raclopride.
    Millan MJ, Newman-Tancredi A, Brocco M, Gobert A, Lejeune F, Audinot V, Rivet JM, Schreiber R, Dekeyne A, Spedding M, Nicolas JP, Peglion JL.
    J Pharmacol Exp Ther; 1998 Oct 19; 287(1):167-86. PubMed ID: 9765336
    [Abstract] [Full Text] [Related]

  • 18. Bivalent molecular probes for dopamine D2-like receptors.
    Huber D, Löber S, Hübner H, Gmeiner P.
    Bioorg Med Chem; 2012 Jan 01; 20(1):455-66. PubMed ID: 22100258
    [Abstract] [Full Text] [Related]

  • 19. Radiosynthesis and evaluation of 18F-labeled dopamine D4-receptor ligands.
    Willmann M, Ermert J, Prante O, Hübner H, Gmeiner P, Neumaier B.
    Nucl Med Biol; 2021 Jan 01; 92():43-52. PubMed ID: 32718750
    [Abstract] [Full Text] [Related]

  • 20. 18F-Labeled FAUC 346 and BP 897 derivatives as subtype-selective potential PET radioligands for the dopamine D3 receptor.
    Hocke C, Prante O, Salama I, Hübner H, Löber S, Kuwert T, Gmeiner P.
    ChemMedChem; 2008 May 01; 3(5):788-93. PubMed ID: 18306190
    [Abstract] [Full Text] [Related]

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