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Journal Abstract Search
222 related items for PubMed ID: 24608000
1. New synthesis of 3-(β-D-glucopyranosyl)-5-substituted-1,2,4-triazoles, nanomolar inhibitors of glycogen phosphorylase. Kun S, Bokor É, Varga G, Szőcs B, Páhi A, Czifrák K, Tóth M, Juhász L, Docsa T, Gergely P, Somsák L. Eur J Med Chem; 2014 Apr 09; 76():567-79. PubMed ID: 24608000 [Abstract] [Full Text] [Related]
2. A multidisciplinary study of 3-(β-d-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: Computation, synthesis, crystallography and kinetics reveal new potent inhibitors. Kun S, Begum J, Kyriakis E, Stamati ECV, Barkas TA, Szennyes E, Bokor É, Szabó KE, Stravodimos GA, Sipos Á, Docsa T, Gergely P, Moffatt C, Patraskaki MS, Kokolaki MC, Gkerdi A, Skamnaki VT, Leonidas DD, Somsák L, Hayes JM. Eur J Med Chem; 2018 Mar 10; 147():266-278. PubMed ID: 29453094 [Abstract] [Full Text] [Related]
3. Synthesis of heterocyclic N-(β-D-glucopyranosyl)carboxamides for inhibition of glycogen phosphorylase. Kónya B, Docsa T, Gergely P, Somsák L. Carbohydr Res; 2012 Apr 01; 351():56-63. PubMed ID: 22365837 [Abstract] [Full Text] [Related]
4. C-Glucopyranosyl-1,2,4-triazol-5-ones: synthesis and inhibition of glycogen phosphorylase. Bokor É, Széles Z, Docsa T, Gergely P, Somsák L. Carbohydr Res; 2016 Jun 24; 429():128-34. PubMed ID: 26818133 [Abstract] [Full Text] [Related]
5. Probing the β-pocket of the active site of human liver glycogen phosphorylase with 3-(C-β-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors. Kyriakis E, Solovou TGA, Kun S, Czifrák K, Szőcs B, Juhász L, Bokor É, Stravodimos GA, Kantsadi AL, Chatzileontiadou DSM, Skamnaki VT, Somsák L, Leonidas DD. Bioorg Chem; 2018 Apr 24; 77():485-493. PubMed ID: 29454281 [Abstract] [Full Text] [Related]
6. Synthesis of New C- and N-β-d-Glucopyranosyl Derivatives of Imidazole, 1,2,3-Triazole and Tetrazole, and Their Evaluation as Inhibitors of Glycogen Phosphorylase. Kun S, Bokor É, Sipos Á, Docsa T, Somsák L. Molecules; 2018 Mar 15; 23(3):. PubMed ID: 29543771 [Abstract] [Full Text] [Related]
7. Synthesis of variously coupled conjugates of D-glucose, 1,3,4-oxadiazole, and 1,2,3-triazole for inhibition of glycogen phosphorylase. Kun S, Nagy GZ, Tóth M, Czecze L, Van Nhien AN, Docsa T, Gergely P, Charavgi MD, Skourti PV, Chrysina ED, Patonay T, Somsák L. Carbohydr Res; 2011 Sep 06; 346(12):1427-38. PubMed ID: 21470596 [Abstract] [Full Text] [Related]
11. N-(4-Substituted-benzoyl)-N'-(β-d-glucopyranosyl)ureas as inhibitors of glycogen phosphorylase: Synthesis and evaluation by kinetic, crystallographic, and molecular modelling methods. Nagy V, Felföldi N, Kónya B, Praly JP, Docsa T, Gergely P, Chrysina ED, Tiraidis C, Kosmopoulou MN, Alexacou KM, Konstantakaki M, Leonidas DD, Zographos SE, Oikonomakos NG, Kozmon S, Tvaroška I, Somsák L. Bioorg Med Chem; 2012 Mar 01; 20(5):1801-16. PubMed ID: 22325154 [Abstract] [Full Text] [Related]
12. Efficient atropodiastereoselective access to 5,5'-bis-1,2,3-triazoles: studies on 1-glucosylated 5-halogeno 1,2,3-triazoles and their 5-substituted derivatives as glycogen phosphorylase inhibitors. Goyard D, Chajistamatiou AS, Sotiropoulou AI, Chrysina ED, Praly JP, Vidal S. Chemistry; 2014 Apr 25; 20(18):5423-32. PubMed ID: 24677199 [Abstract] [Full Text] [Related]
13. Synthesis, In Silico and Kinetics Evaluation of N-(β-d-glucopyranosyl)-2-arylimidazole-4(5)-carboxamides and N-(β-d-glucopyranosyl)-4(5)-arylimidazole-2-carboxamides as Glycogen Phosphorylase Inhibitors. Homolya L, Mathomes RT, Varga L, Docsa T, Juhász L, Hayes JM, Somsák L. Int J Mol Sci; 2024 Apr 23; 25(9):. PubMed ID: 38731811 [Abstract] [Full Text] [Related]
14. Glucopyranosylidene-spiro-iminothiazolidinone, a new bicyclic ring system: synthesis, derivatization, and evaluation for inhibition of glycogen phosphorylase by enzyme kinetic and crystallographic methods. Czifrák K, Páhi A, Deák S, Kiss-Szikszai A, Kövér KE, Docsa T, Gergely P, Alexacou KM, Papakonstantinou M, Leonidas DD, Zographos SE, Chrysina ED, Somsák L. Bioorg Med Chem; 2014 Aug 01; 22(15):4028-41. PubMed ID: 25009003 [Abstract] [Full Text] [Related]
15. Synthesis of substituted 2-(β-D-glucopyranosyl)-benzimidazoles and their evaluation as inhibitors of glycogen phosphorylase. Bokor É, Szilágyi E, Docsa T, Gergely P, Somsák L. Carbohydr Res; 2013 Nov 15; 381():179-86. PubMed ID: 23419607 [Abstract] [Full Text] [Related]
16. Nanomolar Inhibitors of Glycogen Phosphorylase Based on β-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study. Bokor É, Kyriakis E, Solovou TGA, Koppány C, Kantsadi AL, Szabó KE, Szakács A, Stravodimos GA, Docsa T, Skamnaki VT, Zographos SE, Gergely P, Leonidas DD, Somsák L. J Med Chem; 2017 Nov 22; 60(22):9251-9262. PubMed ID: 28925695 [Abstract] [Full Text] [Related]
17. C-Glucopyranosyl-1,2,4-triazoles As New Potent Inhibitors of Glycogen Phosphorylase. Bokor E, Docsa T, Gergely P, Somsák L. ACS Med Chem Lett; 2013 Jul 11; 4(7):612-5. PubMed ID: 24900719 [Abstract] [Full Text] [Related]
18. Synthesis of oleanolic acid dimers as inhibitors of glycogen phosphorylase. Cheng K, Liu J, Sun H, Xie J. Chem Biodivers; 2010 Mar 11; 7(3):690-7. PubMed ID: 20232331 [Abstract] [Full Text] [Related]