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Journal Abstract Search

372 related items for PubMed ID: 24632005

  • 1. The many faces of autophagy dysfunction in Huntington's disease: from mechanism to therapy.
    Cortes CJ, La Spada AR.
    Drug Discov Today; 2014 Jul; 19(7):963-71. PubMed ID: 24632005
    [Abstract] [Full Text] [Related]

  • 2. Degradation of misfolded proteins by autophagy: is it a strategy for Huntington's disease treatment?
    Lin F, Qin ZH.
    J Huntingtons Dis; 2013 Jul; 2(2):149-57. PubMed ID: 25063512
    [Abstract] [Full Text] [Related]

  • 3. Endoplasmic reticulum stress: The cause and solution to Huntington's disease?
    Jiang Y, Chadwick SR, Lajoie P.
    Brain Res; 2016 Oct 01; 1648(Pt B):650-657. PubMed ID: 27040914
    [Abstract] [Full Text] [Related]

  • 4. Targeting the proteostasis network in Huntington's disease.
    Soares TR, Reis SD, Pinho BR, Duchen MR, Oliveira JMA.
    Ageing Res Rev; 2019 Jan 01; 49():92-103. PubMed ID: 30502498
    [Abstract] [Full Text] [Related]

  • 5. Autophagy in Huntington disease and huntingtin in autophagy.
    Martin DD, Ladha S, Ehrnhoefer DE, Hayden MR.
    Trends Neurosci; 2015 Jan 01; 38(1):26-35. PubMed ID: 25282404
    [Abstract] [Full Text] [Related]

  • 6. Proteostasis in Huntington's disease: disease mechanisms and therapeutic opportunities.
    Harding RJ, Tong YF.
    Acta Pharmacol Sin; 2018 May 01; 39(5):754-769. PubMed ID: 29620053
    [Abstract] [Full Text] [Related]

  • 7. Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies.
    Sarkar S, Ravikumar B, Floto RA, Rubinsztein DC.
    Cell Death Differ; 2009 Jan 01; 16(1):46-56. PubMed ID: 18636076
    [Abstract] [Full Text] [Related]

  • 8. Primary cilia and autophagic dysfunction in Huntington's disease.
    Kaliszewski M, Knott AB, Bossy-Wetzel E.
    Cell Death Differ; 2015 Sep 01; 22(9):1413-24. PubMed ID: 26160070
    [Abstract] [Full Text] [Related]

  • 9. Role of chaperone-mediated autophagy in degrading Huntington's disease-associated huntingtin protein.
    Qi L, Zhang XD.
    Acta Biochim Biophys Sin (Shanghai); 2014 Feb 01; 46(2):83-91. PubMed ID: 24323530
    [Abstract] [Full Text] [Related]

  • 10. The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation.
    Wong YC, Holzbaur EL.
    J Neurosci; 2014 Jan 22; 34(4):1293-305. PubMed ID: 24453320
    [Abstract] [Full Text] [Related]

  • 11. Converging pathways in the occurrence of endoplasmic reticulum (ER) stress in Huntington's disease.
    Vidal R, Caballero B, Couve A, Hetz C.
    Curr Mol Med; 2011 Feb 22; 11(1):1-12. PubMed ID: 21189122
    [Abstract] [Full Text] [Related]

  • 12. Huntington's disease: degradation of mutant huntingtin by autophagy.
    Sarkar S, Rubinsztein DC.
    FEBS J; 2008 Sep 22; 275(17):4263-70. PubMed ID: 18637946
    [Abstract] [Full Text] [Related]

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  • 15. IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux.
    Lee H, Noh JY, Oh Y, Kim Y, Chang JW, Chung CW, Lee ST, Kim M, Ryu H, Jung YK.
    Hum Mol Genet; 2012 Jan 01; 21(1):101-14. PubMed ID: 21954231
    [Abstract] [Full Text] [Related]

  • 16. Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease.
    Martinez-Vicente M, Talloczy Z, Wong E, Tang G, Koga H, Kaushik S, de Vries R, Arias E, Harris S, Sulzer D, Cuervo AM.
    Nat Neurosci; 2010 May 01; 13(5):567-76. PubMed ID: 20383138
    [Abstract] [Full Text] [Related]

  • 17. TFEB dysregulation as a driver of autophagy dysfunction in neurodegenerative disease: Molecular mechanisms, cellular processes, and emerging therapeutic opportunities.
    Cortes CJ, La Spada AR.
    Neurobiol Dis; 2019 Feb 01; 122():83-93. PubMed ID: 29852219
    [Abstract] [Full Text] [Related]

  • 18. Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies.
    Ciechanover A, Kwon YT.
    Exp Mol Med; 2015 Mar 13; 47(3):e147. PubMed ID: 25766616
    [Abstract] [Full Text] [Related]

  • 19. Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy.
    Ravikumar B, Duden R, Rubinsztein DC.
    Hum Mol Genet; 2002 May 01; 11(9):1107-17. PubMed ID: 11978769
    [Abstract] [Full Text] [Related]

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