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Journal Abstract Search

392 related items for PubMed ID: 24670687

  • 1. Cytotoxicity of paclitaxel in breast cancer is due to chromosome missegregation on multipolar spindles.
    Zasadil LM, Andersen KA, Yeum D, Rocque GB, Wilke LG, Tevaarwerk AJ, Raines RT, Burkard ME, Weaver BA.
    Sci Transl Med; 2014 Mar 26; 6(229):229ra43. PubMed ID: 24670687
    [Abstract] [Full Text] [Related]

  • 2. Diverse microtubule-targeted anticancer agents kill cells by inducing chromosome missegregation on multipolar spindles.
    Zhou AS, Tucker JB, Scribano CM, Lynch AR, Carlsen CL, Pop-Vicas ST, Pattaswamy SM, Burkard ME, Weaver BA.
    PLoS Biol; 2023 Oct 26; 21(10):e3002339. PubMed ID: 37883329
    [Abstract] [Full Text] [Related]

  • 3. CENP-E Inhibition Induces Chromosomal Instability and Synergizes with Diverse Microtubule-Targeting Agents in Breast Cancer.
    Tucker JB, Carlsen CL, Scribano CM, Pattaswamy SM, Burkard ME, Weaver BA.
    Cancer Res; 2024 Aug 15; 84(16):2674-2689. PubMed ID: 38832939
    [Abstract] [Full Text] [Related]

  • 4. Chromosomal instability sensitizes patient breast tumors to multipolar divisions induced by paclitaxel.
    Scribano CM, Wan J, Esbona K, Tucker JB, Lasek A, Zhou AS, Zasadil LM, Molini R, Fitzgerald J, Lager AM, Laffin JJ, Correia-Staudt K, Wisinski KB, Tevaarwerk AJ, O'Regan R, McGregor SM, Fowler AM, Chappell RJ, Bugni TS, Burkard ME, Weaver BA.
    Sci Transl Med; 2021 Sep 08; 13(610):eabd4811. PubMed ID: 34516829
    [Abstract] [Full Text] [Related]

  • 5. Antagonizing the spindle assembly checkpoint silencing enhances paclitaxel and Navitoclax-mediated apoptosis with distinct mechanistic.
    Henriques AC, Silva PMA, Sarmento B, Bousbaa H.
    Sci Rep; 2021 Feb 18; 11(1):4139. PubMed ID: 33603057
    [Abstract] [Full Text] [Related]

  • 6. Curcumin disrupts mitotic spindle structure and induces micronucleation in MCF-7 breast cancer cells.
    Holy JM.
    Mutat Res; 2002 Jun 27; 518(1):71-84. PubMed ID: 12063069
    [Abstract] [Full Text] [Related]

  • 7. Multiple cancer testis antigens function to support tumor cell mitotic fidelity.
    Cappell KM, Sinnott R, Taus P, Maxfield K, Scarbrough M, Whitehurst AW.
    Mol Cell Biol; 2012 Oct 27; 32(20):4131-40. PubMed ID: 22869527
    [Abstract] [Full Text] [Related]

  • 8. Protein kinase C β inhibition by enzastaurin leads to mitotic missegregation and preferential cytotoxicity toward colorectal cancer cells with chromosomal instability (CIN).
    Ouaret D, Larsen AK.
    Cell Cycle; 2014 Oct 27; 13(17):2697-706. PubMed ID: 25486357
    [Abstract] [Full Text] [Related]

  • 9. Improving breast cancer sensitivity to paclitaxel by increasing aneuploidy.
    Rodrigues-Ferreira S, Nehlig A, Moindjie H, Monchecourt C, Seiler C, Marangoni E, Chateau-Joubert S, Dujaric ME, Servant N, Asselain B, de Cremoux P, Lacroix-Triki M, Arnedos M, Pierga JY, André F, Nahmias C.
    Proc Natl Acad Sci U S A; 2019 Nov 19; 116(47):23691-23697. PubMed ID: 31685623
    [Abstract] [Full Text] [Related]

  • 10. Suppression of spindly delays mitotic exit and exacerbates cell death response of cancer cells treated with low doses of paclitaxel.
    Silva PM, Ribeiro N, Lima RT, Andrade C, Diogo V, Teixeira J, Florindo C, Tavares Á, Vasconcelos MH, Bousbaa H.
    Cancer Lett; 2017 May 28; 394():33-42. PubMed ID: 28249757
    [Abstract] [Full Text] [Related]

  • 11. Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells.
    Koo CY, Giacomini C, Reyes-Corral M, Olmos Y, Tavares IA, Marson CM, Linardopoulos S, Tutt AN, Morris JDH.
    Mol Cancer Ther; 2017 Nov 28; 16(11):2410-2421. PubMed ID: 28830982
    [Abstract] [Full Text] [Related]

  • 12. Curcumin-induced mitotic arrest is characterized by spindle abnormalities, defects in chromosomal congression and DNA damage.
    Blakemore LM, Boes C, Cordell R, Manson MM.
    Carcinogenesis; 2013 Feb 28; 34(2):351-60. PubMed ID: 23125222
    [Abstract] [Full Text] [Related]

  • 13. Prenylated Chalcone 2 Acts as an Antimitotic Agent and Enhances the Chemosensitivity of Tumor Cells to Paclitaxel.
    Fonseca J, Marques S, Silva PM, Brandão P, Cidade H, Pinto MM, Bousbaa H.
    Molecules; 2016 Jul 29; 21(8):. PubMed ID: 27483224
    [Abstract] [Full Text] [Related]

  • 14. Inactivation of the mitotic checkpoint as a determinant of the efficacy of microtubule-targeted drugs in killing human cancer cells.
    Lee EA, Keutmann MK, Dowling ML, Harris E, Chan G, Kao GD.
    Mol Cancer Ther; 2004 Jun 29; 3(6):661-9. PubMed ID: 15210851
    [Abstract] [Full Text] [Related]

  • 15. The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth.
    Jordan MA, Kamath K, Manna T, Okouneva T, Miller HP, Davis C, Littlefield BA, Wilson L.
    Mol Cancer Ther; 2005 Jul 29; 4(7):1086-95. PubMed ID: 16020666
    [Abstract] [Full Text] [Related]

  • 16. Arsenite-induced mitotic death involves stress response and is independent of tubulin polymerization.
    Taylor BF, McNeely SC, Miller HL, States JC.
    Toxicol Appl Pharmacol; 2008 Jul 15; 230(2):235-46. PubMed ID: 18485433
    [Abstract] [Full Text] [Related]

  • 17. Limitations of an ex vivo breast cancer model for studying the mechanism of action of the anticancer drug paclitaxel.
    Urbaniak A, Piña-Oviedo S, Yuan Y, Huczyński A, Chambers TC.
    Eur J Pharmacol; 2021 Jan 15; 891():173780. PubMed ID: 33271152
    [Abstract] [Full Text] [Related]

  • 18. How Taxol/paclitaxel kills cancer cells.
    Weaver BA.
    Mol Biol Cell; 2014 Sep 15; 25(18):2677-81. PubMed ID: 25213191
    [Abstract] [Full Text] [Related]

  • 19. Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity.
    Giannakakou P, Robey R, Fojo T, Blagosklonny MV.
    Oncogene; 2001 Jun 28; 20(29):3806-13. PubMed ID: 11439344
    [Abstract] [Full Text] [Related]

  • 20. Evaluation of 2',4'-dihydroxy-3,4,5-trimethoxychalcone as antimitotic agent that induces mitotic catastrophe in MCF-7 breast cancer cells.
    Masawang K, Pedro M, Cidade H, Reis RM, Neves MP, Corrêa AG, Sudprasert W, Bousbaa H, Pinto MM.
    Toxicol Lett; 2014 Sep 02; 229(2):393-401. PubMed ID: 24968064
    [Abstract] [Full Text] [Related]

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