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Journal Abstract Search


341 related items for PubMed ID: 2467676

  • 1. Further studies on the pharmacologic effects of the 7-hydroxy catabolite of methotrexate in the L1210 murine leukemia cell.
    Seither RL, Rape TJ, Goldman ID.
    Biochem Pharmacol; 1989 Mar 01; 38(5):815-22. PubMed ID: 2467676
    [Abstract] [Full Text] [Related]

  • 2. Folate-pool interconversions and inhibition of biosynthetic processes after exposure of L1210 leukemia cells to antifolates. Experimental and network thermodynamic analyses of the role of dihydrofolate polyglutamylates in antifolate action in cells.
    Seither RL, Trent DF, Mikulecky DC, Rape TJ, Goldman ID.
    J Biol Chem; 1989 Oct 15; 264(29):17016-23. PubMed ID: 2529254
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  • 3. Biochemical factors in the selectivity of leucovorin rescue: selective inhibition of leucovorin reactivation of dihydrofolate reductase and leucovorin utilization in purine and pyrimidine biosynthesis by methotrexate and dihydrofolate polyglutamates.
    Goldman ID, Matherly LH.
    NCI Monogr; 1987 Oct 15; (5):17-26. PubMed ID: 2448654
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  • 4. Interconversion of tetrahydrofolate cofactors to dihydrofolate induced by trimetrexate after suppression of thymidylate synthase by fluorodeoxyuridine in L1210 leukemia cells.
    Seither RL, Rape TJ, Goldman ID.
    Biochem Pharmacol; 1992 Jun 23; 43(12):2647-54. PubMed ID: 1385949
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  • 5. Antifolate polyglutamylation and competitive drug displacement at dihydrofolate reductase as important elements in leucovorin rescue in L1210 cells.
    Matherly LH, Barlowe CK, Goldman ID.
    Cancer Res; 1986 Feb 23; 46(2):588-93. PubMed ID: 2416428
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  • 10. Synthesis of methotrexate polyglutamates in L1210 murine leukemia cells.
    Whitehead VM.
    Cancer Res; 1977 Feb 23; 37(2):408-12. PubMed ID: 832265
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  • 11. Formation of 7-hydroxymethotrexate polyglutamyl derivatives and their cytotoxicity in human chronic myelogenous leukemia cells, in vitro.
    Fabre G, Goldman ID.
    Cancer Res; 1985 Jan 23; 45(1):80-5. PubMed ID: 2578101
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  • 12. Interaction of methotrexate polyglutamates and dihydrofolate during leucovorin rescue in a human breast cancer cell line (MCF-7).
    Allegra CJ, Boarman D.
    Cancer Res; 1990 Jun 15; 50(12):3574-8. PubMed ID: 1692762
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  • 13. The role of methotrexate and dihydrofolate polyglutamates in the enhancement of fluorouracil action by methotrexate.
    Fernandes DJ, Moroson BA, Bertino JR.
    Cancer Treat Rep; 1981 Jun 15; 65 Suppl 1():29-35. PubMed ID: 6173121
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  • 14. The effects on 4-aminoantifolates on 5-formyltetrahydrofolate metabolism in L1210 cells. A biochemical basis of the selectivity of leucovorin rescue.
    Matherly LH, Barlowe CK, Phillips VM, Goldman ID.
    J Biol Chem; 1987 Jan 15; 262(2):710-7. PubMed ID: 2948949
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  • 16. Biochemical and biological studies on 2-desamino-2-methylaminopterin, an antifolate the polyglutamates of which are more potent than the monoglutamate against three key enzymes of folate metabolism.
    Rosowsky A, Galivan J, Beardsley GP, Bader H, O'Connor BM, Russello O, Moroson BA, DeYarman MT, Kerwar SS, Freisheim JH.
    Cancer Res; 1992 Apr 15; 52(8):2148-55. PubMed ID: 1313737
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  • 17. Rescue effect of exogenous reduced folates on methotrexate polyglutamylation and dihydrofolate reductase activity in L1210 cells.
    Balińska M.
    Acta Biochim Pol; 1988 Apr 15; 35(3):199-205. PubMed ID: 2469275
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  • 18. The mechanism of transport of the multitargeted antifolate (MTA) and its cross-resistance pattern in cells with markedly impaired transport of methotrexate.
    Zhao R, Babani S, Gao F, Liu L, Goldman ID.
    Clin Cancer Res; 2000 Sep 15; 6(9):3687-95. PubMed ID: 10999762
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  • 19. Depletion of 5,10-methylenetetrahydrofolate and 10-formyltetrahydrofolate by methotrexate in cultured hepatoma cells.
    Rhee MS, Coward JK, Galivan J.
    Mol Pharmacol; 1992 Nov 15; 42(5):909-16. PubMed ID: 1435754
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  • 20. Rate and extent of interconversion of tetrahydrofolate cofactors to dihydrofolate after cessation of dihydrofolate reductase activity in stationary versus log phase L1210 leukemia cells.
    Trent DF, Seither RL, Goldman ID.
    J Biol Chem; 1991 Mar 25; 266(9):5445-9. PubMed ID: 1825999
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