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Journal Abstract Search


334 related items for PubMed ID: 24696094

  • 1. Effect of bitopertin, a glycine reuptake inhibitor, on negative symptoms of schizophrenia: a randomized, double-blind, proof-of-concept study.
    Umbricht D, Alberati D, Martin-Facklam M, Borroni E, Youssef EA, Ostland M, Wallace TL, Knoflach F, Dorflinger E, Wettstein JG, Bausch A, Garibaldi G, Santarelli L.
    JAMA Psychiatry; 2014 Jun; 71(6):637-46. PubMed ID: 24696094
    [Abstract] [Full Text] [Related]

  • 2. A phase II/III trial of bitopertin monotherapy compared with placebo in patients with an acute exacerbation of schizophrenia - results from the CandleLyte study.
    Bugarski-Kirola D, Wang A, Abi-Saab D, Blättler T.
    Eur Neuropsychopharmacol; 2014 Jul; 24(7):1024-36. PubMed ID: 24735806
    [Abstract] [Full Text] [Related]

  • 3. Efficacy and safety of adjunctive bitopertin versus placebo in patients with suboptimally controlled symptoms of schizophrenia treated with antipsychotics: results from three phase 3, randomised, double-blind, parallel-group, placebo-controlled, multicentre studies in the SearchLyte clinical trial programme.
    Bugarski-Kirola D, Iwata N, Sameljak S, Reid C, Blaettler T, Millar L, Marques TR, Garibaldi G, Kapur S.
    Lancet Psychiatry; 2016 Dec; 3(12):1115-1128. PubMed ID: 27816567
    [Abstract] [Full Text] [Related]

  • 4. Evaluation of the effects of bitopertin (RG1678) on cardiac repolarization: a thorough corrected QT study in healthy male volunteers.
    Hofmann C, Banken L, Hahn M, Swearingen D, Nagel S, Martin-Facklam M.
    Clin Ther; 2012 Oct; 34(10):2061-71. PubMed ID: 22980315
    [Abstract] [Full Text] [Related]

  • 5. Bitopertin in Negative Symptoms of Schizophrenia-Results From the Phase III FlashLyte and DayLyte Studies.
    Bugarski-Kirola D, Blaettler T, Arango C, Fleischhacker WW, Garibaldi G, Wang A, Dixon M, Bressan RA, Nasrallah H, Lawrie S, Napieralski J, Ochi-Lohmann T, Reid C, Marder SR.
    Biol Psychiatry; 2017 Jul 01; 82(1):8-16. PubMed ID: 28117049
    [Abstract] [Full Text] [Related]

  • 6. A double-blind randomized study assessing safety and efficacy following one-year adjunctive treatment with bitopertin, a glycine reuptake inhibitor, in Japanese patients with schizophrenia.
    Hirayasu Y, Sato S, Takahashi H, Iida S, Shuto N, Yoshida S, Funatogawa T, Yamada T, Higuchi T.
    BMC Psychiatry; 2016 Mar 15; 16():66. PubMed ID: 26980460
    [Abstract] [Full Text] [Related]

  • 7. The selective glycine uptake inhibitor org 25935 as an adjunctive treatment to atypical antipsychotics in predominant persistent negative symptoms of schizophrenia: results from the GIANT trial.
    Schoemaker JH, Jansen WT, Schipper J, Szegedi A.
    J Clin Psychopharmacol; 2014 Apr 15; 34(2):190-8. PubMed ID: 24525661
    [Abstract] [Full Text] [Related]

  • 8. A multicenter, add-on randomized controlled trial of low-dose d-serine for negative and cognitive symptoms of schizophrenia.
    Weiser M, Heresco-Levy U, Davidson M, Javitt DC, Werbeloff N, Gershon AA, Abramovich Y, Amital D, Doron A, Konas S, Levkovitz Y, Liba D, Teitelbaum A, Mashiach M, Zimmerman Y.
    J Clin Psychiatry; 2012 Jun 15; 73(6):e728-34. PubMed ID: 22795211
    [Abstract] [Full Text] [Related]

  • 9. Efficacy and safety of the glycine transporter type-1 inhibitor AMG 747 for the treatment of negative symptoms associated with schizophrenia.
    Dunayevich E, Buchanan RW, Chen CY, Yang J, Nilsen J, Dietrich JM, Sun H, Marder S.
    Schizophr Res; 2017 Apr 15; 182():90-97. PubMed ID: 27789188
    [Abstract] [Full Text] [Related]

  • 10. Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to antipsychotics for the treatment of schizophrenia.
    Tsai G, Lane HY, Yang P, Chong MY, Lange N.
    Biol Psychiatry; 2004 Mar 01; 55(5):452-6. PubMed ID: 15023571
    [Abstract] [Full Text] [Related]

  • 11. The retinoid X receptor agonist bexarotene relieves positive symptoms of schizophrenia: a 6-week, randomized, double-blind, placebo-controlled multicenter trial.
    Lerner V, Miodownik C, Gibel A, Sirota P, Bush I, Elliot H, Benatov R, Ritsner MS.
    J Clin Psychiatry; 2013 Dec 01; 74(12):1224-32. PubMed ID: 24434091
    [Abstract] [Full Text] [Related]

  • 12. Improvement of negative and positive symptoms in treatment-refractory schizophrenia: a double-blind, randomized, placebo-controlled trial with memantine as add-on therapy to clozapine.
    de Lucena D, Fernandes BS, Berk M, Dodd S, Medeiros DW, Pedrini M, Kunz M, Gomes FA, Giglio LF, Lobato MI, Belmonte-de-Abreu PS, Gama CS.
    J Clin Psychiatry; 2009 Oct 01; 70(10):1416-23. PubMed ID: 19906345
    [Abstract] [Full Text] [Related]

  • 13. Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to clozapine for the treatment of schizophrenia.
    Lane HY, Huang CL, Wu PL, Liu YC, Chang YC, Lin PY, Chen PW, Tsai G.
    Biol Psychiatry; 2006 Sep 15; 60(6):645-9. PubMed ID: 16780811
    [Abstract] [Full Text] [Related]

  • 14. Effects of the glycine reuptake inhibitors bitopertin and RG7118 on glycine in cerebrospinal fluid: results of two proofs of mechanism studies in healthy volunteers.
    Hofmann C, Pizzagalli F, Boetsch C, Alberati D, Ereshefsky L, Jhee S, Patat A, Boutouyrie-Dumont B, Martin-Facklam M.
    Psychopharmacology (Berl); 2016 Jul 15; 233(13):2429-39. PubMed ID: 27178435
    [Abstract] [Full Text] [Related]

  • 15. Neurophysiological Effects of Bitopertin in Schizophrenia.
    Kantrowitz JT, Nolan KA, Epstein ML, Lehrfeld N, Shope C, Petkova E, Javitt DC.
    J Clin Psychopharmacol; 2017 Aug 15; 37(4):447-451. PubMed ID: 28590364
    [Abstract] [Full Text] [Related]

  • 16. Schizophrenia drug gets negative results for negative symptoms.
    Kingwell K.
    Nat Rev Drug Discov; 2014 Apr 15; 13(4):244-5. PubMed ID: 24687052
    [No Abstract] [Full Text] [Related]

  • 17. Improvement in mismatch negativity generation during d-serine treatment in schizophrenia: Correlation with symptoms.
    Kantrowitz JT, Epstein ML, Lee M, Lehrfeld N, Nolan KA, Shope C, Petkova E, Silipo G, Javitt DC.
    Schizophr Res; 2018 Jan 15; 191():70-79. PubMed ID: 28318835
    [Abstract] [Full Text] [Related]

  • 18. Measuring social functioning with the personal and social performance scale in patients with acute symptoms of schizophrenia: interpretation of results of a pooled analysis of three Phase III trials of paliperidone extended-release tablets.
    Patrick DL, Burns T, Morosini P, Gagnon DD, Rothman M, Adriaenssen I.
    Clin Ther; 2010 Feb 15; 32(2):275-92. PubMed ID: 20206786
    [Abstract] [Full Text] [Related]

  • 19. Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study.
    Lane HY, Chang YC, Liu YC, Chiu CC, Tsai GE.
    Arch Gen Psychiatry; 2005 Nov 15; 62(11):1196-204. PubMed ID: 16275807
    [Abstract] [Full Text] [Related]

  • 20. Bitopertin: the good news and bad news.
    Goff DC.
    JAMA Psychiatry; 2014 Jun 15; 71(6):621-2. PubMed ID: 24696065
    [No Abstract] [Full Text] [Related]


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