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Journal Abstract Search

214 related items for PubMed ID: 24705403

  • 1. Akt-dependent phosphorylation of hepatic FoxO1 is compartmentalized on a WD40/ProF scaffold and is selectively inhibited by aPKC in early phases of diet-induced obesity.
    Sajan MP, Acevedo-Duncan ME, Standaert ML, Ivey RA, Lee M, Farese RV.
    Diabetes; 2014 Aug; 63(8):2690-701. PubMed ID: 24705403
    [Abstract] [Full Text] [Related]

  • 2. Hepatic insulin resistance in ob/ob mice involves increases in ceramide, aPKC activity, and selective impairment of Akt-dependent FoxO1 phosphorylation.
    Sajan MP, Ivey RA, Lee MC, Farese RV.
    J Lipid Res; 2015 Jan; 56(1):70-80. PubMed ID: 25395359
    [Abstract] [Full Text] [Related]

  • 3. Coordinated regulation of hepatic FoxO1, PGC-1α and SREBP-1c facilitates insulin action and resistance.
    Sajan MP, Lee MC, Foufelle F, Sajan J, Cleland C, Farese RV.
    Cell Signal; 2018 Mar; 43():62-70. PubMed ID: 29269047
    [Abstract] [Full Text] [Related]

  • 4. BMI-related progression of atypical PKC-dependent aberrations in insulin signaling through IRS-1, Akt, FoxO1 and PGC-1α in livers of obese and type 2 diabetic humans.
    Sajan MP, Ivey RA, Farese RV.
    Metabolism; 2015 Nov; 64(11):1454-65. PubMed ID: 26386696
    [Abstract] [Full Text] [Related]

  • 5. Endurance exercise training increases APPL1 expression and improves insulin signaling in the hepatic tissue of diet-induced obese mice, independently of weight loss.
    Marinho R, Ropelle ER, Cintra DE, De Souza CT, Da Silva AS, Bertoli FC, Colantonio E, D'Almeida V, Pauli JR.
    J Cell Physiol; 2012 Jul; 227(7):2917-26. PubMed ID: 21938726
    [Abstract] [Full Text] [Related]

  • 6. PKCλ haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymes.
    Sajan MP, Ivey RA, Lee M, Mastorides S, Jurczak MJ, Samuels VT, Shulman GI, Braun U, Leitges M, Farese RV.
    Mol Endocrinol; 2014 Jul; 28(7):1097-107. PubMed ID: 24877563
    [Abstract] [Full Text] [Related]

  • 7. Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepatic cis-vaccenic acid synthesis in diet-induced obese mice.
    Tripathy S, Jump DB.
    J Lipid Res; 2013 Jan; 54(1):71-84. PubMed ID: 23099444
    [Abstract] [Full Text] [Related]

  • 8. Akt- and Foxo1-interacting WD-repeat-FYVE protein promotes adipogenesis.
    Fritzius T, Moelling K.
    EMBO J; 2008 May 07; 27(9):1399-410. PubMed ID: 18388859
    [Abstract] [Full Text] [Related]

  • 9. Brain Insulin Signaling Is Increased in Insulin-Resistant States and Decreases in FOXOs and PGC-1α and Increases in Aβ1-40/42 and Phospho-Tau May Abet Alzheimer Development.
    Sajan M, Hansen B, Ivey R, Sajan J, Ari C, Song S, Braun U, Leitges M, Farese-Higgs M, Farese RV.
    Diabetes; 2016 Jul 07; 65(7):1892-903. PubMed ID: 26895791
    [Abstract] [Full Text] [Related]

  • 10. Acute exercise reduces hepatic glucose production through inhibition of the Foxo1/HNF-4alpha pathway in insulin resistant mice.
    De Souza CT, Frederico MJ, da Luz G, Cintra DE, Ropelle ER, Pauli JR, Velloso LA.
    J Physiol; 2010 Jun 15; 588(Pt 12):2239-53. PubMed ID: 20421289
    [Abstract] [Full Text] [Related]

  • 11. Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition.
    Singh BK, Sinha RA, Zhou J, Tripathi M, Ohba K, Wang ME, Astapova I, Ghosh S, Hollenberg AN, Gauthier K, Yen PM.
    J Biol Chem; 2016 Jan 01; 291(1):198-214. PubMed ID: 26453307
    [Abstract] [Full Text] [Related]

  • 12. Correction of metabolic abnormalities in a rodent model of obesity, metabolic syndrome, and type 2 diabetes mellitus by inhibitors of hepatic protein kinase C-ι.
    Sajan MP, Nimal S, Mastorides S, Acevedo-Duncan M, Kahn CR, Fields AP, Braun U, Leitges M, Farese RV.
    Metabolism; 2012 Apr 01; 61(4):459-69. PubMed ID: 22225955
    [Abstract] [Full Text] [Related]

  • 13. Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1.
    Lu M, Wan M, Leavens KF, Chu Q, Monks BR, Fernandez S, Ahima RS, Ueki K, Kahn CR, Birnbaum MJ.
    Nat Med; 2012 Feb 19; 18(3):388-95. PubMed ID: 22344295
    [Abstract] [Full Text] [Related]

  • 14. The critical role of atypical protein kinase C in activating hepatic SREBP-1c and NFkappaB in obesity.
    Sajan MP, Standaert ML, Nimal S, Varanasi U, Pastoor T, Mastorides S, Braun U, Leitges M, Farese RV.
    J Lipid Res; 2009 Jun 19; 50(6):1133-45. PubMed ID: 19202134
    [Abstract] [Full Text] [Related]

  • 15. Regulation of glucose metabolism via hepatic forkhead transcription factor 1 (FoxO1) by Morinda citrifolia (noni) in high-fat diet-induced obese mice.
    Nerurkar PV, Nishioka A, Eck PO, Johns LM, Volper E, Nerurkar VR.
    Br J Nutr; 2012 Jul 19; 108(2):218-228. PubMed ID: 22011624
    [Abstract] [Full Text] [Related]

  • 16. Regulation of hepatic insulin-like growth factor-binding protein-1 gene expression by insulin: central role for mammalian target of rapamycin independent of forkhead box O proteins.
    Mounier C, Dumas V, Posner BI.
    Endocrinology; 2006 May 19; 147(5):2383-91. PubMed ID: 16455781
    [Abstract] [Full Text] [Related]

  • 17. Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c.
    Hagiwara A, Cornu M, Cybulski N, Polak P, Betz C, Trapani F, Terracciano L, Heim MH, Rüegg MA, Hall MN.
    Cell Metab; 2012 May 02; 15(5):725-38. PubMed ID: 22521878
    [Abstract] [Full Text] [Related]

  • 18. Identification of Akt-independent regulation of hepatic lipogenesis by mammalian target of rapamycin (mTOR) complex 2.
    Yuan M, Pino E, Wu L, Kacergis M, Soukas AA.
    J Biol Chem; 2012 Aug 24; 287(35):29579-88. PubMed ID: 22773877
    [Abstract] [Full Text] [Related]

  • 19. Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance.
    Wang RH, Kim HS, Xiao C, Xu X, Gavrilova O, Deng CX.
    J Clin Invest; 2011 Nov 24; 121(11):4477-90. PubMed ID: 21965330
    [Abstract] [Full Text] [Related]

  • 20. Mapping MKP-3/FOXO1 interaction and evaluating the effect on gluconeogenesis.
    Jiao P, Feng B, Xu H.
    PLoS One; 2012 Nov 24; 7(7):e41168. PubMed ID: 22848439
    [Abstract] [Full Text] [Related]

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