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222 related items for PubMed ID: 24709998

  • 1. AMP-activated protein kinase suppresses the in vitro and in vivo proliferation of hepatocellular carcinoma.
    Cheng J, Huang T, Li Y, Guo Y, Zhu Y, Wang Q, Tan X, Chen W, Zhang Y, Cheng W, Yamamoto T, Jing X, Huang J.
    PLoS One; 2014; 9(4):e93256. PubMed ID: 24709998
    [Abstract] [Full Text] [Related]

  • 2. AICAR and compound C negatively modulate HCC-induced primary human hepatic stellate cell activation in vitro.
    Böttcher K, Longato L, Marrone G, Mazza G, Ghemtio L, Hall A, Luong TV, Caruso S, Viollet B, Zucman-Rossi J, Pinzani M, Rombouts K.
    Am J Physiol Gastrointest Liver Physiol; 2021 Apr 01; 320(4):G543-G556. PubMed ID: 33406006
    [Abstract] [Full Text] [Related]

  • 3. Metformin and AICAR regulate NANOG expression via the JNK pathway in HepG2 cells independently of AMPK.
    Shen C, Ka SO, Kim SJ, Kim JH, Park BH, Park JH.
    Tumour Biol; 2016 Aug 01; 37(8):11199-208. PubMed ID: 26939902
    [Abstract] [Full Text] [Related]

  • 4. Metformin suppresses hepatocellular carcinoma cell growth through induction of cell cycle G1/G0 phase arrest and p21CIP and p27KIP expression and downregulation of cyclin D1 in vitro and in vivo.
    Cai X, Hu X, Cai B, Wang Q, Li Y, Tan X, Hu H, Chen X, Huang J, Cheng J, Jing X.
    Oncol Rep; 2013 Nov 01; 30(5):2449-57. PubMed ID: 24008375
    [Abstract] [Full Text] [Related]

  • 5. AMP-kinase pathway is involved in tumor necrosis factor alpha-induced lipid accumulation in human hepatoma cells.
    Lv Q, Zhen Q, Liu L, Gao R, Yang S, Zhou H, Goswami R, Li Q.
    Life Sci; 2015 Jun 15; 131():23-9. PubMed ID: 25817233
    [Abstract] [Full Text] [Related]

  • 6. Effect of the AMP-kinase modulators AICAR, metformin and compound C on insulin secretion of INS-1E rat insulinoma cells under standard cell culture conditions.
    Langelueddecke C, Jakab M, Ketterl N, Lehner L, Hufnagl C, Schmidt S, Geibel JP, Fuerst J, Ritter M.
    Cell Physiol Biochem; 2012 Jun 15; 29(1-2):75-86. PubMed ID: 22415077
    [Abstract] [Full Text] [Related]

  • 7. 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) effect on glucose production, but not energy metabolism, is independent of hepatic AMPK in vivo.
    Hasenour CM, Ridley DE, Hughey CC, James FD, Donahue EP, Shearer J, Viollet B, Foretz M, Wasserman DH.
    J Biol Chem; 2014 Feb 28; 289(9):5950-9. PubMed ID: 24403081
    [Abstract] [Full Text] [Related]

  • 8. Metformin suppresses hypoxia-induced stabilization of HIF-1α through reprogramming of oxygen metabolism in hepatocellular carcinoma.
    Zhou X, Chen J, Yi G, Deng M, Liu H, Liang M, Shi B, Fu X, Chen Y, Chen L, He Z, Wang J, Liu J.
    Oncotarget; 2016 Jan 05; 7(1):873-84. PubMed ID: 26621849
    [Abstract] [Full Text] [Related]

  • 9. AMP-activated protein kinase is involved in neural stem cell growth suppression and cell cycle arrest by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside and glucose deprivation by down-regulating phospho-retinoblastoma protein and cyclin D.
    Zang Y, Yu LF, Nan FJ, Feng LY, Li J.
    J Biol Chem; 2009 Mar 06; 284(10):6175-84. PubMed ID: 19144636
    [Abstract] [Full Text] [Related]

  • 10. PCK1 negatively regulates cell cycle progression and hepatoma cell proliferation via the AMPK/p27Kip1 axis.
    Tuo L, Xiang J, Pan X, Hu J, Tang H, Liang L, Xia J, Hu Y, Zhang W, Huang A, Wang K, Tang N.
    J Exp Clin Cancer Res; 2019 Feb 04; 38(1):50. PubMed ID: 30717766
    [Abstract] [Full Text] [Related]

  • 11. Overexpression of CYP2E1 induces HepG2 cells death by the AMP kinase activator 5'-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR).
    Zhuge J.
    Cell Biol Toxicol; 2009 Jun 04; 25(3):253-63. PubMed ID: 18473182
    [Abstract] [Full Text] [Related]

  • 12. Negative regulation of Sirtuin 1 by AMP-activated protein kinase promotes metformin-induced senescence in hepatocellular carcinoma xenografts.
    Zhou X, Chen J, Chen L, Feng X, Liu Z, Hu L, Zeng Z, Jia X, Liang M, Shi B, Yi G, Liu J.
    Cancer Lett; 2017 Dec 28; 411():1-11. PubMed ID: 28964787
    [Abstract] [Full Text] [Related]

  • 13. 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase.
    Rattan R, Giri S, Singh AK, Singh I.
    J Biol Chem; 2005 Nov 25; 280(47):39582-93. PubMed ID: 16176927
    [Abstract] [Full Text] [Related]

  • 14. Hemistepsin A Inhibits Cell Proliferation and Induces G0/G1-Phase Arrest, Cellular Senescence and Apoptosis Via the AMPK and p53/p21 Signals in Human Hepatocellular Carcinoma.
    Baek SY, Hwang UW, Suk HY, Kim YW.
    Biomolecules; 2020 May 04; 10(5):. PubMed ID: 32375410
    [Abstract] [Full Text] [Related]

  • 15. microRNA-448 inhibits stemness maintenance and self-renewal of hepatocellular carcinoma stem cells through the MAGEA6-mediated AMPK signaling pathway.
    Guo JC, Yang YJ, Zhang JQ, Guo M, Xiang L, Yu SF, Ping H, Zhuo L.
    J Cell Physiol; 2019 Dec 04; 234(12):23461-23474. PubMed ID: 31232474
    [Abstract] [Full Text] [Related]

  • 16. Simvastatin-induced cell cycle arrest through inhibition of STAT3/SKP2 axis and activation of AMPK to promote p27 and p21 accumulation in hepatocellular carcinoma cells.
    Wang ST, Ho HJ, Lin JT, Shieh JJ, Wu CY.
    Cell Death Dis; 2017 Feb 23; 8(2):e2626. PubMed ID: 28230855
    [Abstract] [Full Text] [Related]

  • 17. AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC.
    Sajan MP, Bandyopadhyay G, Miura A, Standaert ML, Nimal S, Longnus SL, Van Obberghen E, Hainault I, Foufelle F, Kahn R, Braun U, Leitges M, Farese RV.
    Am J Physiol Endocrinol Metab; 2010 Feb 23; 298(2):E179-92. PubMed ID: 19887597
    [Abstract] [Full Text] [Related]

  • 18. The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN).
    Gao J, Xiong R, Xiong D, Zhao W, Zhang S, Yin T, Zhang X, Jiang G, Yin Z.
    Med Sci Monit; 2018 Nov 26; 24():8533-8543. PubMed ID: 30474622
    [Abstract] [Full Text] [Related]

  • 19. AMP-activated protein kinase inhibits IL-6-stimulated inflammatory response in human liver cells by suppressing phosphorylation of signal transducer and activator of transcription 3 (STAT3).
    Nerstedt A, Johansson A, Andersson CX, Cansby E, Smith U, Mahlapuu M.
    Diabetologia; 2010 Nov 26; 53(11):2406-16. PubMed ID: 20652679
    [Abstract] [Full Text] [Related]

  • 20. Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662.
    Ducommun S, Ford RJ, Bultot L, Deak M, Bertrand L, Kemp BE, Steinberg GR, Sakamoto K.
    Am J Physiol Endocrinol Metab; 2014 Mar 26; 306(6):E688-96. PubMed ID: 24425763
    [Abstract] [Full Text] [Related]

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