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229 related items for PubMed ID: 24722985

  • 1. The accessory factor Nef links HIV-1 to Tec/Btk kinases in an Src homology 3 domain-dependent manner.
    Tarafdar S, Poe JA, Smithgall TE.
    J Biol Chem; 2014 May 30; 289(22):15718-28. PubMed ID: 24722985
    [Abstract] [Full Text] [Related]

  • 2. HIV-1 Nef dimers short-circuit immune receptor signaling by activating Tec-family kinases at the host cell membrane.
    Li WF, Aryal M, Shu ST, Smithgall TE.
    J Biol Chem; 2020 Apr 10; 295(15):5163-5174. PubMed ID: 32144207
    [Abstract] [Full Text] [Related]

  • 3. The HIV-1 protein Nef activates the Tec family kinase Btk by stabilizing an intermolecular SH3-SH2 domain interaction.
    Aryal M, Lin D, Regan K, Du S, Shi H, Alvarado JJ, Ilina TV, Andreotti AH, Smithgall TE.
    Sci Signal; 2022 Sep 20; 15(752):eabn8359. PubMed ID: 36126115
    [Abstract] [Full Text] [Related]

  • 4. Structure, function, and inhibitor targeting of HIV-1 Nef-effector kinase complexes.
    Staudt RP, Alvarado JJ, Emert-Sedlak LA, Shi H, Shu ST, Wales TE, Engen JR, Smithgall TE.
    J Biol Chem; 2020 Oct 30; 295(44):15158-15171. PubMed ID: 32862141
    [Abstract] [Full Text] [Related]

  • 5. Nef alleles from all major HIV-1 clades activate Src-family kinases and enhance HIV-1 replication in an inhibitor-sensitive manner.
    Narute PS, Smithgall TE.
    PLoS One; 2012 Oct 30; 7(2):e32561. PubMed ID: 22393415
    [Abstract] [Full Text] [Related]

  • 6. Simian immunodeficiency virus and human immunodeficiency virus type 1 nef proteins show distinct patterns and mechanisms of Src kinase activation.
    Greenway AL, Dutartre H, Allen K, McPhee DA, Olive D, Collette Y.
    J Virol; 1999 Jul 30; 73(7):6152-8. PubMed ID: 10364375
    [Abstract] [Full Text] [Related]

  • 7. The proline rich region of the Tec homology domain of ITK regulates its activity.
    Hao S, August A.
    FEBS Lett; 2002 Aug 14; 525(1-3):53-8. PubMed ID: 12163161
    [Abstract] [Full Text] [Related]

  • 8. The solution structure and intramolecular associations of the Tec kinase SRC homology 3 domain.
    Pursglove SE, Mulhern TD, Mackay JP, Hinds MG, Booker GW.
    J Biol Chem; 2002 Jan 04; 277(1):755-62. PubMed ID: 11684687
    [Abstract] [Full Text] [Related]

  • 9. Reconstitution of Btk signaling by the atypical tec family tyrosine kinases Bmx and Txk.
    Tomlinson MG, Kurosaki T, Berson AE, Fujii GH, Johnston JA, Bolen JB.
    J Biol Chem; 1999 May 07; 274(19):13577-85. PubMed ID: 10224128
    [Abstract] [Full Text] [Related]

  • 10. The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism.
    Dutartre H, Harris M, Olive D, Collette Y.
    Virology; 1998 Aug 01; 247(2):200-11. PubMed ID: 9705913
    [Abstract] [Full Text] [Related]

  • 11. The Tec family kinase Itk exists as a folded monomer in vivo.
    Qi Q, August A.
    J Biol Chem; 2009 Oct 23; 284(43):29882-92. PubMed ID: 19717557
    [Abstract] [Full Text] [Related]

  • 12. Oligomerization is required for HIV-1 Nef-induced activation of the Src family protein-tyrosine kinase, Hck.
    Ye H, Choi HJ, Poe J, Smithgall TE.
    Biochemistry; 2004 Dec 21; 43(50):15775-84. PubMed ID: 15595833
    [Abstract] [Full Text] [Related]

  • 13. Remodeling of HIV-1 Nef Structure by Src-Family Kinase Binding.
    Moroco JA, Alvarado JJ, Staudt RP, Shi H, Wales TE, Smithgall TE, Engen JR.
    J Mol Biol; 2018 Feb 02; 430(3):310-321. PubMed ID: 29258818
    [Abstract] [Full Text] [Related]

  • 14. Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain.
    Lee CH, Saksela K, Mirza UA, Chait BT, Kuriyan J.
    Cell; 1996 Jun 14; 85(6):931-42. PubMed ID: 8681387
    [Abstract] [Full Text] [Related]

  • 15. Expression and function of Tec, Itk, and Btk in lymphocytes: evidence for a unique role for Tec.
    Tomlinson MG, Kane LP, Su J, Kadlecek TA, Mollenauer MN, Weiss A.
    Mol Cell Biol; 2004 Mar 14; 24(6):2455-66. PubMed ID: 14993283
    [Abstract] [Full Text] [Related]

  • 16. Affinity of Src family kinase SH3 domains for HIV Nef in vitro does not predict kinase activation by Nef in vivo.
    Briggs SD, Lerner EC, Smithgall TE.
    Biochemistry; 2000 Jan 25; 39(3):489-95. PubMed ID: 10642173
    [Abstract] [Full Text] [Related]

  • 17. Identification of phosphorylation sites within the SH3 domains of Tec family tyrosine kinases.
    Nore BF, Mattsson PT, Antonsson P, Bäckesjö CM, Westlund A, Lennartsson J, Hansson H, Löw P, Rönnstrand L, Smith CI.
    Biochim Biophys Acta; 2003 Feb 21; 1645(2):123-32. PubMed ID: 12573241
    [Abstract] [Full Text] [Related]

  • 18. Characterization of Itk tyrosine kinase: contribution of noncatalytic domains to enzymatic activity.
    Hawkins J, Marcy A.
    Protein Expr Purif; 2001 Jul 21; 22(2):211-9. PubMed ID: 11437596
    [Abstract] [Full Text] [Related]

  • 19. The role of Tec protein-tyrosine kinase in T cell signaling.
    Yang WC, Ghiotto M, Barbarat B, Olive D.
    J Biol Chem; 1999 Jan 08; 274(2):607-17. PubMed ID: 9872994
    [Abstract] [Full Text] [Related]

  • 20. Interaction with the Src homology (SH3-SH2) region of the Src-family kinase Hck structures the HIV-1 Nef dimer for kinase activation and effector recruitment.
    Alvarado JJ, Tarafdar S, Yeh JI, Smithgall TE.
    J Biol Chem; 2014 Oct 10; 289(41):28539-53. PubMed ID: 25122770
    [Abstract] [Full Text] [Related]

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