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Journal Abstract Search

251 related items for PubMed ID: 2472880

  • 1.
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  • 2. Biochemical studies on PT523, a potent nonpolyglutamatable antifolate, in cultured cells.
    Rhee MS, Galivan J, Wright JE, Rosowsky A.
    Mol Pharmacol; 1994 Apr; 45(4):783-91. PubMed ID: 7514264
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  • 3. Biochemical and growth inhibition studies of methotrexate and aminopterin analogues containing a tetrazole ring in place of the gamma-carboxyl group.
    McGuire JJ, Russell CA, Bolanowska WE, Freitag CM, Jones CS, Kalman TI.
    Cancer Res; 1990 Mar 15; 50(6):1726-31. PubMed ID: 2306727
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  • 4. gamma-Fluoromethotrexate: synthesis and biological activity of a potent inhibitor of dihydrofolate reductase with greatly diminished ability to form poly-gamma-glutamates.
    Galivan J, Inglese J, McGuire JJ, Nimec Z, Coward JK.
    Proc Natl Acad Sci U S A; 1985 May 15; 82(9):2598-602. PubMed ID: 2581252
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  • 6. Impact of polyglutamation on sensitivity to raltitrexed and methotrexate in relation to drug-induced inhibition of de novo thymidylate and purine biosynthesis in CCRF-CEM cell lines.
    Barnes MJ, Estlin EJ, Taylor GA, Aherne GW, Hardcastle A, McGuire JJ, Calvete JA, Lunec J, Pearson AD, Newell DR.
    Clin Cancer Res; 1999 Sep 15; 5(9):2548-58. PubMed ID: 10499632
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  • 7. DL-beta,beta-difluoroglutamic acid mediates position-dependent enhancement or termination of pteroylpoly(gamma-glutamate) synthesis catalyzed by folylpolyglutamate synthetase.
    McGuire JJ, Hart BP, Haile WH, Rhee MS, Galivan J, Coward JK.
    Arch Biochem Biophys; 1995 Aug 20; 321(2):319-28. PubMed ID: 7646057
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  • 8. Determinants of the sensitivity of human small-cell lung cancer cell lines to methotrexate.
    Curt GA, Jolivet J, Carney DN, Bailey BD, Drake JC, Clendeninn NJ, Chabner BA.
    J Clin Invest; 1985 Oct 20; 76(4):1323-9. PubMed ID: 2414316
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  • 12. Biochemical factors in the selectivity of leucovorin rescue: selective inhibition of leucovorin reactivation of dihydrofolate reductase and leucovorin utilization in purine and pyrimidine biosynthesis by methotrexate and dihydrofolate polyglutamates.
    Goldman ID, Matherly LH.
    NCI Monogr; 1987 Oct 20; (5):17-26. PubMed ID: 2448654
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  • 13. Impaired polyglutamylation of methotrexate as a cause of resistance in CCRF-CEM cells after short-term, high-dose treatment with this drug.
    Pizzorno G, Mini E, Coronnello M, McGuire JJ, Moroson BA, Cashmore AR, Dreyer RN, Lin JT, Mazzei T, Periti P.
    Cancer Res; 1988 Apr 15; 48(8):2149-55. PubMed ID: 2450647
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  • 14. Antifolate polyglutamylation and competitive drug displacement at dihydrofolate reductase as important elements in leucovorin rescue in L1210 cells.
    Matherly LH, Barlowe CK, Goldman ID.
    Cancer Res; 1986 Feb 15; 46(2):588-93. PubMed ID: 2416428
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  • 15. Role of methotrexate polyglutamates in methotrexate- and sequential methotrexate-5-fluorouracil-mediated cell kill.
    McGuire JJ, Mini E, Hsieh P, Bertino JR.
    Cancer Res; 1985 Dec 15; 45(12 Pt 1):6395-400. PubMed ID: 2415244
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  • 16. Biological properties of fluoroglutamate-containing analogs of folates and methotrexate with altered capacities to form poly (gamma-glutamate) metabolites.
    McGuire JJ, Hart BP, Haile WH, Magee KJ, Rhee M, Bolanowska WE, Russell C, Galivan J, Paul B, Coward JK.
    Biochem Pharmacol; 1996 Oct 25; 52(8):1295-303. PubMed ID: 8937438
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  • 17. Intrinsic resistance of cervical squamous cell carcinoma cell lines to methotrexate (MTX) as a result of decreased accumulation of intracellular MTX polyglutamates.
    Barakat RR, Li WW, Lovelace C, Bertino JR.
    Gynecol Oncol; 1993 Oct 25; 51(1):54-60. PubMed ID: 7694891
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  • 18. Antitumor activity of antifolate inhibitors of thymidylate and purine synthesis in human soft tissue sarcoma cell lines with intrinsic resistance to methotrexate.
    Li WW, Tong WP, Bertino JR.
    Clin Cancer Res; 1995 Jun 25; 1(6):631-6. PubMed ID: 9816025
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  • 20. Identification of a membrane-associated folate-binding protein in human leukemic CCRF-CEM cells with transport-related methotrexate resistance.
    Jansen G, Westerhof GR, Kathmann I, Rademaker BC, Rijksen G, Schornagel JH.
    Cancer Res; 1989 May 01; 49(9):2455-9. PubMed ID: 2706633
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