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243 related items for PubMed ID: 24733293

  • 1. Glucagon stimulates hepatic FGF21 secretion through a PKA- and EPAC-dependent posttranscriptional mechanism.
    Cyphert HA, Alonge KM, Ippagunta SM, Hillgartner FB.
    PLoS One; 2014; 9(4):e94996. PubMed ID: 24733293
    [Abstract] [Full Text] [Related]

  • 2. Cyclic adenosine 5'-monophosphate-stimulated neurotensin secretion is mediated through Rap1 downstream of both Epac and protein kinase A signaling pathways.
    Li J, O'Connor KL, Cheng X, Mei FC, Uchida T, Townsend CM, Evers BM.
    Mol Endocrinol; 2007 Jan; 21(1):159-71. PubMed ID: 17068197
    [Abstract] [Full Text] [Related]

  • 3. Glucagon and Insulin Cooperatively Stimulate Fibroblast Growth Factor 21 Gene Transcription by Increasing the Expression of Activating Transcription Factor 4.
    Alonge KM, Meares GP, Hillgartner FB.
    J Biol Chem; 2017 Mar 31; 292(13):5239-5252. PubMed ID: 28188284
    [Abstract] [Full Text] [Related]

  • 4. Glucagon stimulates ghrelin secretion through the activation of MAPK and EPAC and potentiates the effect of norepinephrine.
    Gagnon J, Anini Y.
    Endocrinology; 2013 Feb 31; 154(2):666-74. PubMed ID: 23307791
    [Abstract] [Full Text] [Related]

  • 5. Activation of exchange protein directly activated by cyclic adenosine monophosphate and protein kinase A regulate common and distinct steps in promoting plasma membrane exocytic and granule-to-granule fusions in rat islet beta cells.
    Kwan EP, Gao X, Leung YM, Gaisano HY.
    Pancreas; 2007 Oct 31; 35(3):e45-54. PubMed ID: 17895835
    [Abstract] [Full Text] [Related]

  • 6. Enhanced Rap1 activation and insulin secretagogue properties of an acetoxymethyl ester of an Epac-selective cyclic AMP analog in rat INS-1 cells: studies with 8-pCPT-2'-O-Me-cAMP-AM.
    Chepurny OG, Leech CA, Kelley GG, Dzhura I, Dzhura E, Li X, Rindler MJ, Schwede F, Genieser HG, Holz GG.
    J Biol Chem; 2009 Apr 17; 284(16):10728-36. PubMed ID: 19244230
    [Abstract] [Full Text] [Related]

  • 7. Suppressor of cytokine signaling-3 is a glucagon-inducible inhibitor of PKA activity and gluconeogenic gene expression in hepatocytes.
    Gaudy AM, Clementi AH, Campbell JS, Smrcka AV, Mooney RA.
    J Biol Chem; 2010 Dec 31; 285(53):41356-65. PubMed ID: 20978125
    [Abstract] [Full Text] [Related]

  • 8. Epac is involved in cAMP-stimulated proglucagon expression and hormone production but not hormone secretion in pancreatic alpha- and intestinal L-cell lines.
    Islam D, Zhang N, Wang P, Li H, Brubaker PL, Gaisano HY, Wang Q, Jin T.
    Am J Physiol Endocrinol Metab; 2009 Jan 31; 296(1):E174-81. PubMed ID: 18854429
    [Abstract] [Full Text] [Related]

  • 9. Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor.
    Rangarajan S, Enserink JM, Kuiperij HB, de Rooij J, Price LS, Schwede F, Bos JL.
    J Cell Biol; 2003 Feb 17; 160(4):487-93. PubMed ID: 12578910
    [Abstract] [Full Text] [Related]

  • 10. Differential signaling of cyclic AMP: opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation.
    Mei FC, Qiao J, Tsygankova OM, Meinkoth JL, Quilliam LA, Cheng X.
    J Biol Chem; 2002 Mar 29; 277(13):11497-504. PubMed ID: 11801596
    [Abstract] [Full Text] [Related]

  • 11. EPAC activation inhibits acetaldehyde-induced activation and proliferation of hepatic stellate cell via Rap1.
    Yang Y, Yang F, Wu X, Lv X, Li J.
    Can J Physiol Pharmacol; 2016 May 29; 94(5):498-507. PubMed ID: 26854595
    [Abstract] [Full Text] [Related]

  • 12. The augmentation of insulin-like growth factor-I messenger ribonucleic acid in cultured rat hepatocytes: activation of protein kinase-A and -C is necessary, but not sufficient.
    Kachra Z, Yang CR, Posner BI.
    Endocrinology; 1994 Feb 29; 134(2):702-8. PubMed ID: 7507834
    [Abstract] [Full Text] [Related]

  • 13. Cyclic AMP-dependent protein kinase A and EPAC mediate VIP and secretin stimulation of PAK4 and activation of Na+,K+-ATPase in pancreatic acinar cells.
    Ramos-Alvarez I, Lee L, Jensen RT.
    Am J Physiol Gastrointest Liver Physiol; 2019 Feb 01; 316(2):G263-G277. PubMed ID: 30520694
    [Abstract] [Full Text] [Related]

  • 14. Pyruvate Upregulates Hepatic FGF21 Expression by Activating PDE and Inhibiting cAMP-Epac-CREB Signaling Pathway.
    Zhao YY, Zhang LJ, Liang XY, Zhang XC, Chang JR, Shi M, Liu H, Zhou Y, Sun Z, Zhao YF.
    Int J Mol Sci; 2022 May 14; 23(10):. PubMed ID: 35628302
    [Abstract] [Full Text] [Related]

  • 15. Role of Epac and protein kinase A in thyrotropin-induced gene expression in primary thyrocytes.
    van Staveren WC, Beeckman S, Tomás G, Dom G, Hébrant A, Delys L, Vliem MJ, Trésallet C, Andry G, Franc B, Libert F, Dumont JE, Maenhaut C.
    Exp Cell Res; 2012 Mar 10; 318(5):444-52. PubMed ID: 22240166
    [Abstract] [Full Text] [Related]

  • 16. Cooperation between cAMP signalling and sulfonylurea in insulin secretion.
    Shibasaki T, Takahashi T, Takahashi H, Seino S.
    Diabetes Obes Metab; 2014 Sep 10; 16 Suppl 1():118-25. PubMed ID: 25200305
    [Abstract] [Full Text] [Related]

  • 17. The cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD).
    Banales JM, Masyuk TV, Gradilone SA, Masyuk AI, Medina JF, LaRusso NF.
    Hepatology; 2009 Jan 10; 49(1):160-74. PubMed ID: 19065671
    [Abstract] [Full Text] [Related]

  • 18. Elevation of cyclic AMP in Jurkat T-cells provokes distinct transcriptional responses through the protein kinase A (PKA) and exchange protein activated by cyclic AMP (EPAC) pathways.
    Fuld S, Borland G, Yarwood SJ.
    Exp Cell Res; 2005 Sep 10; 309(1):161-73. PubMed ID: 15963501
    [Abstract] [Full Text] [Related]

  • 19. Cyclic AMP (cAMP)-mediated stimulation of adipocyte differentiation requires the synergistic action of Epac- and cAMP-dependent protein kinase-dependent processes.
    Petersen RK, Madsen L, Pedersen LM, Hallenborg P, Hagland H, Viste K, Døskeland SO, Kristiansen K.
    Mol Cell Biol; 2008 Jun 10; 28(11):3804-16. PubMed ID: 18391018
    [Abstract] [Full Text] [Related]

  • 20. Epac, in synergy with cAMP-dependent protein kinase (PKA), is required for cAMP-mediated mitogenesis.
    Hochbaum D, Hong K, Barila G, Ribeiro-Neto F, Altschuler DL.
    J Biol Chem; 2008 Feb 22; 283(8):4464-8. PubMed ID: 18063584
    [Abstract] [Full Text] [Related]

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