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202 related items for PubMed ID: 24740159

  • 1. Sonic Hedgehog activation is implicated in diosgenin-induced megakaryocytic differentiation of human erythroleukemia cells.
    Ghezali L, Liagre B, Limami Y, Beneytout JL, Leger DY.
    PLoS One; 2014; 9(4):e95016. PubMed ID: 24740159
    [Abstract] [Full Text] [Related]

  • 2. Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro.
    You M, Varona-Santos J, Singh S, Robbins DJ, Savaraj N, Nguyen DM.
    J Thorac Cardiovasc Surg; 2014 Jan; 147(1):508-16. PubMed ID: 24094913
    [Abstract] [Full Text] [Related]

  • 3. A proteomic approach to the identification of molecular targets in subsequent apoptosis of HEL cells after diosgenin-induced megakaryocytic differentiation.
    Cailleteau C, Liagre B, Beneytout JL.
    J Cell Biochem; 2009 Jul 01; 107(4):785-96. PubMed ID: 19415684
    [Abstract] [Full Text] [Related]

  • 4. A plant steroid, diosgenin, a new megakaryocytic differentiation inducer of HEL cells.
    Beneytout JL, Nappez C, Leboutet MJ, Malinvaud G.
    Biochem Biophys Res Commun; 1995 Feb 06; 207(1):398-404. PubMed ID: 7857294
    [Abstract] [Full Text] [Related]

  • 5. Increased cyclooxygenase-2 and thromboxane synthase expression is implicated in diosgenin-induced megakaryocytic differentiation in human erythroleukemia cells.
    Cailleteau C, Liagre B, Battu S, Jayat-Vignoles C, Beneytout JL.
    Anal Biochem; 2008 Sep 01; 380(1):26-34. PubMed ID: 18549804
    [Abstract] [Full Text] [Related]

  • 6. Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo.
    Wickström M, Dyberg C, Shimokawa T, Milosevic J, Baryawno N, Fuskevåg OM, Larsson R, Kogner P, Zaphiropoulos PG, Johnsen JI.
    Int J Cancer; 2013 Apr 01; 132(7):1516-24. PubMed ID: 22949014
    [Abstract] [Full Text] [Related]

  • 7. Targeting the hedgehog-glioma-associated oncogene homolog pathway inhibits bleomycin-induced lung fibrosis in mice.
    Moshai EF, Wémeau-Stervinou L, Cigna N, Brayer S, Sommé JM, Crestani B, Mailleux AA.
    Am J Respir Cell Mol Biol; 2014 Jul 01; 51(1):11-25. PubMed ID: 24450438
    [Abstract] [Full Text] [Related]

  • 8. Activation of the Sonic Hedgehog pathway in thyroid neoplasms and its potential role in tumor cell proliferation.
    Xu X, Ding H, Rao G, Arora S, Saclarides CP, Esparaz J, Gattuso P, Solorzano CC, Prinz RA.
    Endocr Relat Cancer; 2012 Apr 01; 19(2):167-79. PubMed ID: 22241722
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of hedgehog signaling induces monocytic differentiation of HL-60 cells.
    Bai LY, Weng JR, Lo WJ, Yeh SP, Wu CY, Wang CY, Chiu CF, Lin CW.
    Leuk Lymphoma; 2012 Jun 01; 53(6):1196-202. PubMed ID: 22080758
    [Abstract] [Full Text] [Related]

  • 10. In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.
    Benvenuto M, Masuelli L, De Smaele E, Fantini M, Mattera R, Cucchi D, Bonanno E, Di Stefano E, Frajese GV, Orlandi A, Screpanti I, Gulino A, Modesti A, Bei R.
    Oncotarget; 2016 Feb 23; 7(8):9250-70. PubMed ID: 26843616
    [Abstract] [Full Text] [Related]

  • 11. Hedgehog-signaling is upregulated in non-producing human adrenal adenomas and antagonism of hedgehog-signaling inhibits proliferation of NCI-H295R cells and an immortalized primary human adrenal cell line.
    Werminghaus P, Haase M, Hornsby PJ, Schinner S, Schott M, Malendowicz LK, Lammers BJ, Goretzki PE, Müller-Mattheis V, Markus Giessing, Willenberg HS.
    J Steroid Biochem Mol Biol; 2014 Jan 23; 139():7-15. PubMed ID: 24063979
    [Abstract] [Full Text] [Related]

  • 12. Expressions of sonic hedgehog, patched, smoothened and Gli-1 in human intestinal stromal tumors and their correlation with prognosis.
    Yoshizaki A, Nakayama T, Naito S, Wen CY, Sekine I.
    World J Gastroenterol; 2006 Sep 21; 12(35):5687-91. PubMed ID: 17007023
    [Abstract] [Full Text] [Related]

  • 13. Overexpression of smoothened activates the sonic hedgehog signaling pathway in pancreatic cancer-associated fibroblasts.
    Walter K, Omura N, Hong SM, Griffith M, Vincent A, Borges M, Goggins M.
    Clin Cancer Res; 2010 Mar 15; 16(6):1781-9. PubMed ID: 20215540
    [Abstract] [Full Text] [Related]

  • 14. Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors.
    Dagklis A, Demeyer S, De Bie J, Radaelli E, Pauwels D, Degryse S, Gielen O, Vicente C, Vandepoel R, Geerdens E, Uyttebroeck A, Boeckx N, de Bock CE, Cools J.
    Blood; 2016 Dec 08; 128(23):2642-2654. PubMed ID: 27694322
    [Abstract] [Full Text] [Related]

  • 15. Targeting hedgehog signaling pathway in pediatric tumors: in vitro evaluation of SMO and GLI inhibitors.
    Arnhold V, Boos J, Lanvers-Kaminsky C.
    Cancer Chemother Pharmacol; 2016 Mar 08; 77(3):495-505. PubMed ID: 26781311
    [Abstract] [Full Text] [Related]

  • 16. Hedgehog signaling is a novel therapeutic target in tamoxifen-resistant breast cancer aberrantly activated by PI3K/AKT pathway.
    Ramaswamy B, Lu Y, Teng KY, Nuovo G, Li X, Shapiro CL, Majumder S.
    Cancer Res; 2012 Oct 01; 72(19):5048-59. PubMed ID: 22875023
    [Abstract] [Full Text] [Related]

  • 17. Regulation of DNA damage following termination of Hedgehog (HH) survival signaling at the level of the GLI genes in human colon cancer.
    Agyeman A, Mazumdar T, Houghton JA.
    Oncotarget; 2012 Aug 01; 3(8):854-68. PubMed ID: 23097684
    [Abstract] [Full Text] [Related]

  • 18. Investigating the relationship between cell cycle stage and diosgenin-induced megakaryocytic differentiation of HEL cells using sedimentation field-flow fractionation.
    Cailleteau C, Micallef L, Lepage C, Cardot PJ, Beneytout JL, Liagre B, Battu S.
    Anal Bioanal Chem; 2010 Oct 01; 398(3):1273-83. PubMed ID: 20714892
    [Abstract] [Full Text] [Related]

  • 19. Changes in lipoxygenase activities in human erythroleukemia (HEL) cells during diosgenin-induced differentiation.
    Nappez C, Liagre B, Beneytout JL.
    Cancer Lett; 1995 Sep 04; 96(1):133-40. PubMed ID: 7553601
    [Abstract] [Full Text] [Related]

  • 20. Role of MAPKs and NF-kappaB in diosgenin-induced megakaryocytic differentiation and subsequent apoptosis in HEL cells.
    Leger DY, Liagre B, Beneytout JL.
    Int J Oncol; 2006 Jan 04; 28(1):201-7. PubMed ID: 16327997
    [Abstract] [Full Text] [Related]

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