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Journal Abstract Search

816 related items for PubMed ID: 24768714

  • 1. A dual role for the anti-apoptotic Bcl-2 protein in cancer: mitochondria versus endoplasmic reticulum.
    Akl H, Vervloessem T, Kiviluoto S, Bittremieux M, Parys JB, De Smedt H, Bultynck G.
    Biochim Biophys Acta; 2014 Oct; 1843(10):2240-52. PubMed ID: 24768714
    [Abstract] [Full Text] [Related]

  • 2. HA14-1 potentiates apoptosis in B-cell cancer cells sensitive to a peptide disrupting IP 3 receptor / Bcl-2 complexes.
    Akl H, La Rovere RM, Janssens A, Vandenberghe P, Parys JB, Bultynck G.
    Int J Dev Biol; 2015 Oct; 59(7-9):391-8. PubMed ID: 26260683
    [Abstract] [Full Text] [Related]

  • 3. Inositol 1,4,5-trisphosphate receptor-isoform diversity in cell death and survival.
    Ivanova H, Vervliet T, Missiaen L, Parys JB, De Smedt H, Bultynck G.
    Biochim Biophys Acta; 2014 Oct; 1843(10):2164-83. PubMed ID: 24642269
    [Abstract] [Full Text] [Related]

  • 4. Bcl-2 regulation of the inositol 1,4,5-trisphosphate receptor and calcium signaling in normal and malignant lymphocytes: potential new target for cancer treatment.
    Greenberg EF, Lavik AR, Distelhorst CW.
    Biochim Biophys Acta; 2014 Oct; 1843(10):2205-10. PubMed ID: 24642270
    [Abstract] [Full Text] [Related]

  • 5. Constitutive IP3 signaling underlies the sensitivity of B-cell cancers to the Bcl-2/IP3 receptor disruptor BIRD-2.
    Bittremieux M, La Rovere RM, Akl H, Martines C, Welkenhuyzen K, Dubron K, Baes M, Janssens A, Vandenberghe P, Laurenti L, Rietdorf K, Morciano G, Pinton P, Mikoshiba K, Bootman MD, Efremov DG, De Smedt H, Parys JB, Bultynck G.
    Cell Death Differ; 2019 Mar; 26(3):531-547. PubMed ID: 29899382
    [Abstract] [Full Text] [Related]

  • 6. IP3R2 levels dictate the apoptotic sensitivity of diffuse large B-cell lymphoma cells to an IP3R-derived peptide targeting the BH4 domain of Bcl-2.
    Akl H, Monaco G, La Rovere R, Welkenhuyzen K, Kiviluoto S, Vervliet T, Molgó J, Distelhorst CW, Missiaen L, Mikoshiba K, Parys JB, De Smedt H, Bultynck G.
    Cell Death Dis; 2013 May 16; 4(5):e632. PubMed ID: 23681227
    [Abstract] [Full Text] [Related]

  • 7. The selective BH4-domain biology of Bcl-2-family members: IP3Rs and beyond.
    Monaco G, Vervliet T, Akl H, Bultynck G.
    Cell Mol Life Sci; 2013 Apr 16; 70(7):1171-83. PubMed ID: 22955373
    [Abstract] [Full Text] [Related]

  • 8. BIRD-2, a BH4-domain-targeting peptide of Bcl-2, provokes Bax/Bak-independent cell death in B-cell cancers through mitochondrial Ca2+-dependent mPTP opening.
    Kerkhofs M, La Rovere R, Welkenhuysen K, Janssens A, Vandenberghe P, Madesh M, Parys JB, Bultynck G.
    Cell Calcium; 2021 Mar 16; 94():102333. PubMed ID: 33450506
    [Abstract] [Full Text] [Related]

  • 9. Reciprocal sensitivity of diffuse large B-cell lymphoma cells to Bcl-2 inhibitors BIRD-2 versus venetoclax.
    Vervloessem T, Akl H, Tousseyn T, De Smedt H, Parys JB, Bultynck G.
    Oncotarget; 2017 Dec 19; 8(67):111656-111671. PubMed ID: 29340082
    [Abstract] [Full Text] [Related]

  • 10. A synthetic peptide targeting the BH4 domain of Bcl-2 induces apoptosis in multiple myeloma and follicular lymphoma cells alone or in combination with agents targeting the BH3-binding pocket of Bcl-2.
    Lavik AR, Zhong F, Chang MJ, Greenberg E, Choudhary Y, Smith MR, McColl KS, Pink J, Reu FJ, Matsuyama S, Distelhorst CW.
    Oncotarget; 2015 Sep 29; 6(29):27388-402. PubMed ID: 26317541
    [Abstract] [Full Text] [Related]

  • 11. Regulation of the ryanodine receptor by anti-apoptotic Bcl-2 is independent of its BH3-domain-binding properties.
    Vervliet T, Lemmens I, Welkenhuyzen K, Tavernier J, Parys JB, Bultynck G.
    Biochem Biophys Res Commun; 2015 Jul 31; 463(3):174-9. PubMed ID: 25957473
    [Abstract] [Full Text] [Related]

  • 12. Targeting Bcl-2-IP3 receptor interaction to treat cancer: A novel approach inspired by nearly a century treating cancer with adrenal corticosteroid hormones.
    Distelhorst CW.
    Biochim Biophys Acta Mol Cell Res; 2018 Nov 31; 1865(11 Pt B):1795-1804. PubMed ID: 30053503
    [Abstract] [Full Text] [Related]

  • 13. The Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavage.
    Schulman JJ, Wright FA, Kaufmann T, Wojcikiewicz RJH.
    J Biol Chem; 2013 Aug 30; 288(35):25340-25349. PubMed ID: 23884412
    [Abstract] [Full Text] [Related]

  • 14. The type 2 inositol 1,4,5-trisphosphate receptor, emerging functions for an intriguing Ca²⁺-release channel.
    Vervloessem T, Yule DI, Bultynck G, Parys JB.
    Biochim Biophys Acta; 2015 Sep 30; 1853(9):1992-2005. PubMed ID: 25499268
    [Abstract] [Full Text] [Related]

  • 15. Bcl-2 and FKBP12 bind to IP3 and ryanodine receptors at overlapping sites: the complexity of protein-protein interactions for channel regulation.
    Vervliet T, Parys JB, Bultynck G.
    Biochem Soc Trans; 2015 Jun 30; 43(3):396-404. PubMed ID: 26009182
    [Abstract] [Full Text] [Related]

  • 16. The BH4 domain of anti-apoptotic Bcl-XL, but not that of the related Bcl-2, limits the voltage-dependent anion channel 1 (VDAC1)-mediated transfer of pro-apoptotic Ca2+ signals to mitochondria.
    Monaco G, Decrock E, Arbel N, van Vliet AR, La Rovere RM, De Smedt H, Parys JB, Agostinis P, Leybaert L, Shoshan-Barmatz V, Bultynck G.
    J Biol Chem; 2015 Apr 03; 290(14):9150-61. PubMed ID: 25681439
    [Abstract] [Full Text] [Related]

  • 17. A double point mutation at residues Ile14 and Val15 of Bcl-2 uncovers a role for the BH4 domain in both protein stability and function.
    Monaco G, La Rovere R, Karamanou S, Welkenhuyzen K, Ivanova H, Vandermarliere E, Di Martile M, Del Bufalo D, De Smedt H, Parys JB, Economou A, Bultynck G.
    FEBS J; 2018 Jan 03; 285(1):127-145. PubMed ID: 29131545
    [Abstract] [Full Text] [Related]

  • 18. Targeting Bcl-2 based on the interaction of its BH4 domain with the inositol 1,4,5-trisphosphate receptor.
    Rong YP, Barr P, Yee VC, Distelhorst CW.
    Biochim Biophys Acta; 2009 Jun 03; 1793(6):971-8. PubMed ID: 19056433
    [Abstract] [Full Text] [Related]

  • 19. Recent advances in canonical versus non-canonical Ca2+-signaling-related anti-apoptotic Bcl-2 functions and prospects for cancer treatment.
    Cauwelier C, de Ridder I, Bultynck G.
    Biochim Biophys Acta Mol Cell Res; 2024 Jun 03; 1871(5):119713. PubMed ID: 38521468
    [Abstract] [Full Text] [Related]

  • 20. The BH4 domain of Bcl-2 orthologues from different classes of vertebrates can act as an evolutionary conserved inhibitor of IP3 receptor channels.
    Ivanova H, Luyten T, Decrock E, Vervliet T, Leybaert L, Parys JB, Bultynck G.
    Cell Calcium; 2017 Mar 03; 62():41-46. PubMed ID: 28179071
    [Abstract] [Full Text] [Related]

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