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Journal Abstract Search

249 related items for PubMed ID: 24797889

  • 1. Novel shikonin derivatives targeting tubulin as anticancer agents.
    Guo J, Chen XF, Liu J, Lin HY, Han HW, Liu HC, Huang SC, Shahla BK, Kulek A, Qi JL, Wang XM, Ling LJ, Yang YH.
    Chem Biol Drug Des; 2014 Nov; 84(5):603-15. PubMed ID: 24797889
    [Abstract] [Full Text] [Related]

  • 2. Design, Synthesis, and Biological Evaluation of Chalcone-Containing Shikonin Derivatives as Inhibitors of Tubulin Polymerization.
    Qiu HY, Wang F, Wang X, Sun WX, Qi JL, Pang YJ, Yang RW, Lu GH, Wang XM, Yang YH.
    ChemMedChem; 2017 Mar 07; 12(5):399-406. PubMed ID: 28211616
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and biological evaluation of heterocyclic carboxylic acyl shikonin derivatives.
    Wang XM, Lin HY, Kong WY, Guo J, Shi J, Huang SC, Qi JL, Yang RW, Gu HW, Yang YH.
    Chem Biol Drug Des; 2014 Mar 07; 83(3):334-43. PubMed ID: 24118825
    [Abstract] [Full Text] [Related]

  • 4. A potent anticancer agent of shikonin derivative targeting tubulin.
    Baloch SK, Ma L, Xu GH, Bai LF, Zhao H, Tang CY, Pang YJ, Yang RW, Wang XM, Lu GH, Yang YH.
    Chirality; 2015 Mar 07; 27(3):274-80. PubMed ID: 25663187
    [Abstract] [Full Text] [Related]

  • 5. Synthesis of aryl dihydrothiazol acyl shikonin ester derivatives as anticancer agents through microtubule stabilization.
    Lin HY, Li ZK, Bai LF, Baloch SK, Wang F, Qiu HY, Wang X, Qi JL, Yang RW, Wang XM, Yang YH.
    Biochem Pharmacol; 2015 Jul 15; 96(2):93-106. PubMed ID: 25957661
    [Abstract] [Full Text] [Related]

  • 6. Design and characterization of α-lipoic acyl shikonin ester twin drugs as tubulin and PDK1 dual inhibitors.
    Lin HY, Han HW, Sun WX, Yang YS, Tang CY, Lu GH, Qi JL, Wang XM, Yang YH.
    Eur J Med Chem; 2018 Jan 20; 144():137-150. PubMed ID: 29268130
    [Abstract] [Full Text] [Related]

  • 7. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
    [Abstract] [Full Text] [Related]

  • 8. Development of a novel class of tubulin inhibitors with promising anticancer activities.
    Xi J, Zhu X, Feng Y, Huang N, Luo G, Mao Y, Han X, Tian W, Wang G, Han X, Luo R, Huang Z, An J.
    Mol Cancer Res; 2013 Aug 01; 11(8):856-64. PubMed ID: 23666368
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis and biological evaluation of benzoylacrylic acid shikonin ester derivatives as irreversible dual inhibitors of tubulin and EGFR.
    Sun WX, Han HW, Yang MK, Wen ZL, Wang YS, Fu JY, Lu YT, Wang MY, Bao JX, Lu GH, Qi JL, Wang XM, Lin HY, Yang YH.
    Bioorg Med Chem; 2019 Dec 01; 27(23):115153. PubMed ID: 31648877
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors.
    Qin YJ, Li YJ, Jiang AQ, Yang MR, Zhu QZ, Dong H, Zhu HL.
    Eur J Med Chem; 2015 Apr 13; 94():447-57. PubMed ID: 25828827
    [Abstract] [Full Text] [Related]

  • 11. Induction of apoptosis through tubulin inhibition in human cancer cells by new chromene-based chalcones.
    Aryapour H, Riazi GH, Ahmadian S, Foroumadi A, Mahdavi M, Emami S.
    Pharm Biol; 2012 Dec 13; 50(12):1551-60. PubMed ID: 22984888
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and biological evaluation of novel shikonin-benzo[b]furan derivatives as tubulin polymerization inhibitors targeting the colchicine binding site.
    Shao YY, Yin Y, Lian BP, Leng JF, Xia YZ, Kong LY.
    Eur J Med Chem; 2020 Mar 15; 190():112105. PubMed ID: 32035399
    [Abstract] [Full Text] [Related]

  • 13. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
    Yan J, Pang Y, Sheng J, Wang Y, Chen J, Hu J, Huang L, Li X.
    Biochem Pharmacol; 2015 Sep 01; 97(1):51-61. PubMed ID: 26212540
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
    Xu S, An B, Li Y, Luo X, Li X, Jia X.
    Bioorg Med Chem Lett; 2018 Jun 01; 28(10):1769-1775. PubMed ID: 29673981
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and biological evaluation of a series of podophyllotoxins derivatives as a class of potent antitubulin agents.
    Liu Y, Wei D, Zhao Y, Cheng W, Lu Y, Ma Y, Li X, Han C, Wei Y, Cao H, Zhao C.
    Bioorg Med Chem; 2012 Nov 01; 20(21):6285-95. PubMed ID: 23022053
    [Abstract] [Full Text] [Related]

  • 16. Synthesis, biological evaluation and molecular modeling of 1,3,4-thiadiazol-2-amide derivatives as novel antitubulin agents.
    Li YJ, Qin YJ, Makawana JA, Wang YT, Zhang YQ, Zhang YL, Yang MR, Jiang AQ, Zhu HL.
    Bioorg Med Chem; 2014 Aug 01; 22(15):4312-22. PubMed ID: 24909678
    [Abstract] [Full Text] [Related]

  • 17. New benzimidazole-2-urea derivates as tubulin inhibitors.
    Wang W, Kong D, Cheng H, Tan L, Zhang Z, Zhuang X, Long H, Zhou Y, Xu Y, Yang X, Ding K.
    Bioorg Med Chem Lett; 2014 Sep 01; 24(17):4250-3. PubMed ID: 25091926
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
    Lai Q, Wang Y, Wang R, Lai W, Tang L, Tao Y, Liu Y, Zhang R, Huang L, Xiang H, Zeng S, Gou L, Chen H, Yao Y, Yang J.
    Eur J Med Chem; 2018 Aug 05; 156():162-179. PubMed ID: 30006162
    [Abstract] [Full Text] [Related]

  • 19. Biological evaluation and molecular modelling study of podophyllotoxin derivatives as potent inhibitors of tubulin polymerization.
    Ma Y, Fang S, Li H, Han C, Lu Y, Zhao Y, Liu Y, Zhao C.
    Chem Biol Drug Des; 2013 Jul 05; 82(1):12-21. PubMed ID: 23786349
    [Abstract] [Full Text] [Related]

  • 20. Indicine N-oxide binds to tubulin at a distinct site and inhibits the assembly of microtubules: a mechanism for its cytotoxic activity.
    Appadurai P, Rathinasamy K.
    Toxicol Lett; 2014 Feb 10; 225(1):66-77. PubMed ID: 24300171
    [Abstract] [Full Text] [Related]

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