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314 related items for PubMed ID: 24806638

  • 1. Leucine facilitates the insulin-stimulated glucose uptake and insulin signaling in skeletal muscle cells: involving mTORC1 and mTORC2.
    Liu H, Liu R, Xiong Y, Li X, Wang X, Ma Y, Guo H, Hao L, Yao P, Liu L, Wang D, Yang X.
    Amino Acids; 2014 Aug; 46(8):1971-9. PubMed ID: 24806638
    [Abstract] [Full Text] [Related]

  • 2. Ceramide inhibits insulin-stimulated Akt phosphorylation through activation of Rheb/mTORC1/S6K signaling in skeletal muscle.
    Hsieh CT, Chuang JH, Yang WC, Yin Y, Lin Y.
    Cell Signal; 2014 Jul; 26(7):1400-8. PubMed ID: 24650522
    [Abstract] [Full Text] [Related]

  • 3. Chronic inhibition of the mTORC1/S6K1 pathway increases insulin-induced PI3K activity but inhibits Akt2 and glucose transport stimulation in 3T3-L1 adipocytes.
    Veilleux A, Houde VP, Bellmann K, Marette A.
    Mol Endocrinol; 2010 Apr; 24(4):766-78. PubMed ID: 20203102
    [Abstract] [Full Text] [Related]

  • 4. mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.
    Le Bacquer O, Queniat G, Gmyr V, Kerr-Conte J, Lefebvre B, Pattou F.
    J Endocrinol; 2013 Jan; 216(1):21-9. PubMed ID: 23092880
    [Abstract] [Full Text] [Related]

  • 5. Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin.
    Takano A, Usui I, Haruta T, Kawahara J, Uno T, Iwata M, Kobayashi M.
    Mol Cell Biol; 2001 Aug; 21(15):5050-62. PubMed ID: 11438661
    [Abstract] [Full Text] [Related]

  • 6. Enhanced skeletal muscle insulin sensitivity after acute resistance-type exercise is upregulated by rapamycin-sensitive mTOR complex 1 inhibition.
    Kido K, Sase K, Yokokawa T, Fujita S.
    Sci Rep; 2020 May 22; 10(1):8509. PubMed ID: 32444657
    [Abstract] [Full Text] [Related]

  • 7. Cellular depletion of atypical PKC{lambda} is associated with enhanced insulin sensitivity and glucose uptake in L6 rat skeletal muscle cells.
    Stretton C, Evans A, Hundal HS.
    Am J Physiol Endocrinol Metab; 2010 Sep 22; 299(3):E402-12. PubMed ID: 20530734
    [Abstract] [Full Text] [Related]

  • 8. Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1.
    Nascimento EB, Snel M, Guigas B, van der Zon GC, Kriek J, Maassen JA, Jazet IM, Diamant M, Ouwens DM.
    Cell Signal; 2010 Jun 22; 22(6):961-7. PubMed ID: 20138985
    [Abstract] [Full Text] [Related]

  • 9. A novel PKB/Akt inhibitor, MK-2206, effectively inhibits insulin-stimulated glucose metabolism and protein synthesis in isolated rat skeletal muscle.
    Lai YC, Liu Y, Jacobs R, Rider MH.
    Biochem J; 2012 Oct 01; 447(1):137-47. PubMed ID: 22793019
    [Abstract] [Full Text] [Related]

  • 10. L-leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the L-leucine-induced up-regulation of system A amino acid transport.
    Peyrollier K, Hajduch E, Blair AS, Hyde R, Hundal HS.
    Biochem J; 2000 Sep 01; 350 Pt 2(Pt 2):361-8. PubMed ID: 10947949
    [Abstract] [Full Text] [Related]

  • 11. An amino acid mixture enhances insulin-stimulated glucose uptake in isolated rat epitrochlearis muscle.
    Kleinert M, Liao YH, Nelson JL, Bernard JR, Wang W, Ivy JL.
    J Appl Physiol (1985); 2011 Jul 01; 111(1):163-9. PubMed ID: 21527668
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  • 13. Ketoisocaproic acid, a metabolite of leucine, suppresses insulin-stimulated glucose transport in skeletal muscle cells in a BCAT2-dependent manner.
    Moghei M, Tavajohi-Fini P, Beatty B, Adegoke OA.
    Am J Physiol Cell Physiol; 2016 Sep 01; 311(3):C518-27. PubMed ID: 27488662
    [Abstract] [Full Text] [Related]

  • 14. Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes.
    Tremblay F, Gagnon A, Veilleux A, Sorisky A, Marette A.
    Endocrinology; 2005 Mar 01; 146(3):1328-37. PubMed ID: 15576463
    [Abstract] [Full Text] [Related]

  • 15. High leptin levels acutely inhibit insulin-stimulated glucose uptake without affecting glucose transporter 4 translocation in l6 rat skeletal muscle cells.
    Sweeney G, Keen J, Somwar R, Konrad D, Garg R, Klip A.
    Endocrinology; 2001 Nov 01; 142(11):4806-12. PubMed ID: 11606447
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  • 17. Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity.
    Lamming DW, Ye L, Katajisto P, Goncalves MD, Saitoh M, Stevens DM, Davis JG, Salmon AB, Richardson A, Ahima RS, Guertin DA, Sabatini DM, Baur JA.
    Science; 2012 Mar 30; 335(6076):1638-43. PubMed ID: 22461615
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  • 19. Acetaldehyde promotes rapamycin-dependent activation of p70(S6K) and glucose uptake despite inhibition of Akt and mTOR in dopaminergic SH-SY5Y human neuroblastoma cells.
    Fang CX, Yang X, Sreejayan N, Ren J.
    Exp Neurol; 2007 Jan 30; 203(1):196-204. PubMed ID: 16962100
    [Abstract] [Full Text] [Related]

  • 20. Amino acids and leucine allow insulin activation of the PKB/mTOR pathway in normal adipocytes treated with wortmannin and in adipocytes from db/db mice.
    Hinault C, Mothe-Satney I, Gautier N, Lawrence JC, Van Obberghen E.
    FASEB J; 2004 Dec 30; 18(15):1894-6. PubMed ID: 15479767
    [Abstract] [Full Text] [Related]

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