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315 related items for PubMed ID: 24812669
1. Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival. Tang CH, Ranatunga S, Kriss CL, Cubitt CL, Tao J, Pinilla-Ibarz JA, Del Valle JR, Hu CC. J Clin Invest; 2014 Jun; 124(6):2585-98. PubMed ID: 24812669 [Abstract] [Full Text] [Related]
2. Development of Tumor-Targeting IRE-1 Inhibitors for B-cell Cancer Therapy. Shao A, Xu Q, Spalek WT, Cain CF, Kang CW, Tang CA, Del Valle JR, Hu CA. Mol Cancer Ther; 2020 Dec; 19(12):2432-2444. PubMed ID: 33051362 [Abstract] [Full Text] [Related]
3. Inhibition of Human Dendritic Cell ER Stress Response Reduces T Cell Alloreactivity Yet Spares Donor Anti-tumor Immunity. Betts BC, Locke FL, Sagatys EM, Pidala J, Walton K, Menges M, Reff J, Saha A, Djeu JY, Kiluk JV, Lee MC, Kim J, Kang CW, Tang CH, Frieling J, Lynch CC, List A, Rodriguez PC, Blazar BR, Conejo-Garcia JR, Del Valle JR, Hu CC, Anasetti C. Front Immunol; 2018 Dec; 9():2887. PubMed ID: 30574153 [Abstract] [Full Text] [Related]
4. XBP-1s Promotes B Cell Pathogenicity in Chronic GVHD by Restraining the Activity of Regulated IRE-1α-Dependent Decay. Choi HJ, Tang CA, Tian L, Wu Y, Sofi MH, Ticer T, Schutt SD, Hu CA, Yu XZ. Front Immunol; 2021 Dec; 12():705484. PubMed ID: 34659198 [Abstract] [Full Text] [Related]
5. Endoplasmic reticulum stress-induced IRE1α activation mediates cross-talk of GSK-3β and XBP-1 to regulate inflammatory cytokine production. Kim S, Joe Y, Kim HJ, Kim YS, Jeong SO, Pae HO, Ryter SW, Surh YJ, Chung HT. J Immunol; 2015 May 01; 194(9):4498-506. PubMed ID: 25821218 [Abstract] [Full Text] [Related]
6. Endoplasmic Reticulum Stress Response Mediator IRE-1α Promotes Host Dendritic Cells in Graft-versus-Host Disease Development. Choi HJ, Wu Y, McDaniel Mims B, Pugel A, Tang CA, Tian L, Hu CA, Yu XZ. J Immunol; 2024 Aug 01; 213(3):384-393. PubMed ID: 38864663 [Abstract] [Full Text] [Related]
7. Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease. Volkmann K, Lucas JL, Vuga D, Wang X, Brumm D, Stiles C, Kriebel D, Der-Sarkissian A, Krishnan K, Schweitzer C, Liu Z, Malyankar UM, Chiovitti D, Canny M, Durocher D, Sicheri F, Patterson JB. J Biol Chem; 2011 Apr 08; 286(14):12743-55. PubMed ID: 21303903 [Abstract] [Full Text] [Related]
8. High-Density Lipoprotein Prevents Endoplasmic Reticulum Stress-Induced Downregulation of Liver LOX-1 Expression. Hong D, Li LF, Gao HC, Wang X, Li CC, Luo Y, Bai YP, Zhang GG. PLoS One; 2015 Apr 08; 10(4):e0124285. PubMed ID: 25923692 [Abstract] [Full Text] [Related]
9. Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers. Zundell JA, Fukumoto T, Lin J, Fatkhudinov N, Nacarelli T, Kossenkov AV, Liu Q, Cassel J, Hu CA, Wu S, Zhang R. Cancer Res; 2021 Oct 15; 81(20):5325-5335. PubMed ID: 34548333 [Abstract] [Full Text] [Related]
10. Dual role of inositol-requiring enzyme 1α (IRE-1α) in Cd-induced apoptosis in human renal tubular epithelial cells: Endoplasmic reticulum stress and STAT3 signaling activation. Chou X, Ma K, Shen Y, Min Z, Wu Q, Sun D. Toxicology; 2021 May 30; 456():152769. PubMed ID: 33813002 [Abstract] [Full Text] [Related]
12. Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma. Mimura N, Fulciniti M, Gorgun G, Tai YT, Cirstea D, Santo L, Hu Y, Fabre C, Minami J, Ohguchi H, Kiziltepe T, Ikeda H, Kawano Y, French M, Blumenthal M, Tam V, Kertesz NL, Malyankar UM, Hokenson M, Pham T, Zeng Q, Patterson JB, Richardson PG, Munshi NC, Anderson KC. Blood; 2012 Jun 14; 119(24):5772-81. PubMed ID: 22538852 [Abstract] [Full Text] [Related]
13. BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha. Lisbona F, Rojas-Rivera D, Thielen P, Zamorano S, Todd D, Martinon F, Glavic A, Kress C, Lin JH, Walter P, Reed JC, Glimcher LH, Hetz C. Mol Cell; 2009 Mar 27; 33(6):679-91. PubMed ID: 19328063 [Abstract] [Full Text] [Related]
14. ATF6 upregulates XBP1S and inhibits ER stress-mediated apoptosis in osteoarthritis cartilage. Guo FJ, Xiong Z, Lu X, Ye M, Han X, Jiang R. Cell Signal; 2014 Feb 27; 26(2):332-42. PubMed ID: 24269637 [Abstract] [Full Text] [Related]
15. Endoplasmic reticulum stress and IRE-1 signaling cause apoptosis in colon cancer cells in response to andrographolide treatment. Banerjee A, Ahmed H, Yang P, Czinn SJ, Blanchard TG. Oncotarget; 2016 Jul 05; 7(27):41432-41444. PubMed ID: 27166181 [Abstract] [Full Text] [Related]
16. Endoplasmic reticulum stress promotes macrophage-derived foam cell formation by up-regulating cluster of differentiation 36 (CD36) expression. Yao S, Miao C, Tian H, Sang H, Yang N, Jiao P, Han J, Zong C, Qin S. J Biol Chem; 2014 Feb 14; 289(7):4032-42. PubMed ID: 24366867 [Abstract] [Full Text] [Related]
17. Reduced response of IRE1α/Xbp-1 signaling pathway to bortezomib contributes to drug resistance in multiple myeloma cells. Xu X, Liu J, Huang B, Chen M, Yuan S, Li X, Li J. Tumori; 2017 May 12; 103(3):261-267. PubMed ID: 27647225 [Abstract] [Full Text] [Related]
18. A novel chemical, STF-083010, reverses tamoxifen-related drug resistance in breast cancer by inhibiting IRE1/XBP1. Ming J, Ruan S, Wang M, Ye D, Fan N, Meng Q, Tian B, Huang T. Oncotarget; 2015 Dec 01; 6(38):40692-703. PubMed ID: 26517687 [Abstract] [Full Text] [Related]
19. Dinaciclib (SCH727965) inhibits the unfolded protein response through a CDK1- and 5-dependent mechanism. Nguyen TK, Grant S. Mol Cancer Ther; 2014 Mar 01; 13(3):662-74. PubMed ID: 24362465 [Abstract] [Full Text] [Related]
20. Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway. Namba T, Chu K, Kodama R, Byun S, Yoon KW, Hiraki M, Mandinova A, Lee SW. Oncotarget; 2015 Aug 21; 6(24):19990-20001. PubMed ID: 26254280 [Abstract] [Full Text] [Related] Page: [Next] [New Search]