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445 related items for PubMed ID: 24818748

  • 1. Emerging roles of the p38 MAPK and PI3K/AKT/mTOR pathways in oncogene-induced senescence.
    Xu Y, Li N, Xiang R, Sun P.
    Trends Biochem Sci; 2014 Jun; 39(6):268-76. PubMed ID: 24818748
    [Abstract] [Full Text] [Related]

  • 2. Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells.
    Pan ST, Qin Y, Zhou ZW, He ZX, Zhang X, Yang T, Yang YX, Wang D, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Jun; 9():1601-26. PubMed ID: 25834400
    [Abstract] [Full Text] [Related]

  • 3. AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy.
    Astle MV, Hannan KM, Ng PY, Lee RS, George AJ, Hsu AK, Haupt Y, Hannan RD, Pearson RB.
    Oncogene; 2012 Apr 12; 31(15):1949-62. PubMed ID: 21909130
    [Abstract] [Full Text] [Related]

  • 4. Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells.
    Wang F, Wang Q, Zhou ZW, Yu SN, Pan ST, He ZX, Zhang X, Wang D, Yang YX, Yang T, Sun T, Li M, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Apr 12; 9():537-60. PubMed ID: 25632222
    [Abstract] [Full Text] [Related]

  • 5. The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells.
    Li JP, Yang YX, Liu QL, Pan ST, He ZX, Zhang X, Yang T, Chen XW, Wang D, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Apr 12; 9():1627-52. PubMed ID: 25834401
    [Abstract] [Full Text] [Related]

  • 6. Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells.
    Wang F, Li H, Yan XG, Zhou ZW, Yi ZG, He ZX, Pan ST, Yang YX, Wang ZZ, Zhang X, Yang T, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Apr 12; 9():575-601. PubMed ID: 25632225
    [Abstract] [Full Text] [Related]

  • 7. Euptox A Induces G1 Arrest and Autophagy via p38 MAPK- and PI3K/Akt/mTOR-Mediated Pathways in Mouse Splenocytes.
    Mo Q, Hu L, Weng J, Zhang Y, Zhou Y, Xu R, Zuo Z, Deng J, Ren Z, Zhong Z, Peng G, Nong X, Wei Y, Hu Y.
    J Histochem Cytochem; 2017 Sep 12; 65(9):543-558. PubMed ID: 28745544
    [Abstract] [Full Text] [Related]

  • 8. The role of the PI3K/Akt/mTOR signalling pathway in human cancers induced by infection with human papillomaviruses.
    Zhang L, Wu J, Ling MT, Zhao L, Zhao KN.
    Mol Cancer; 2015 Apr 17; 14():87. PubMed ID: 26022660
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of Autophagy Promotes Salinomycin-Induced Apoptosis via Reactive Oxygen Species-Mediated PI3K/AKT/mTOR and ERK/p38 MAPK-Dependent Signaling in Human Prostate Cancer Cells.
    Kim KY, Park KI, Kim SH, Yu SN, Park SG, Kim YW, Seo YK, Ma JY, Ahn SC.
    Int J Mol Sci; 2017 May 18; 18(5):. PubMed ID: 28524116
    [Abstract] [Full Text] [Related]

  • 10. A senescence secretory switch mediated by PI3K/AKT/mTOR activation controls chemoprotective endothelial secretory responses.
    Bent EH, Gilbert LA, Hemann MT.
    Genes Dev; 2016 Aug 15; 30(16):1811-21. PubMed ID: 27566778
    [Abstract] [Full Text] [Related]

  • 11. Escape from p21-mediated oncogene-induced senescence leads to cell dedifferentiation and dependence on anti-apoptotic Bcl-xL and MCL1 proteins.
    de Carné Trécesson S, Guillemin Y, Bélanger A, Bernard AC, Preisser L, Ravon E, Gamelin E, Juin P, Barré B, Coqueret O.
    J Biol Chem; 2011 Apr 15; 286(15):12825-38. PubMed ID: 21292770
    [Abstract] [Full Text] [Related]

  • 12. A comprehensive immunohistochemical and molecular approach to the PI3K/AKT/mTOR (phosphoinositide 3-kinase/v-akt murine thymoma viral oncogene/mammalian target of rapamycin) pathway in bladder urothelial carcinoma.
    Korkolopoulou P, Levidou G, Trigka EA, Prekete N, Karlou M, Thymara I, Sakellariou S, Fragkou P, Isaiadis D, Pavlopoulos P, Patsouris E, Saetta AA.
    BJU Int; 2012 Dec 15; 110(11 Pt C):E1237-48. PubMed ID: 23107319
    [Abstract] [Full Text] [Related]

  • 13. G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells.
    Gao N, Flynn DC, Zhang Z, Zhong XS, Walker V, Liu KJ, Shi X, Jiang BH.
    Am J Physiol Cell Physiol; 2004 Aug 15; 287(2):C281-91. PubMed ID: 15028555
    [Abstract] [Full Text] [Related]

  • 14. Impact of oncogenic driver mutations on feedback between the PI3K and MEK pathways in cancer cells.
    Yuen HF, Abramczyk O, Montgomery G, Chan KK, Huang YH, Sasazuki T, Shirasawa S, Gopesh S, Chan KW, Fennell D, Janne P, El-Tanani M, Murray JT.
    Biosci Rep; 2012 Aug 15; 32(4):413-22. PubMed ID: 22668349
    [Abstract] [Full Text] [Related]

  • 15. Involvement of PI3K-AKT-mTOR pathway in protein kinase CKII inhibition-mediated senescence in human colon cancer cells.
    Park JH, Kim JJ, Bae YS.
    Biochem Biophys Res Commun; 2013 Apr 19; 433(4):420-5. PubMed ID: 23523798
    [Abstract] [Full Text] [Related]

  • 16. A functional genetic screen defines the AKT-induced senescence signaling network.
    Chan KT, Blake S, Zhu H, Kang J, Trigos AS, Madhamshettiwar PB, Diesch J, Paavolainen L, Horvath P, Hannan RD, George AJ, Sanij E, Hannan KM, Simpson KJ, Pearson RB.
    Cell Death Differ; 2020 Feb 19; 27(2):725-741. PubMed ID: 31285545
    [Abstract] [Full Text] [Related]

  • 17. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK, Wang ZL, Pan ST, Ding HQ, Au GH, He ZX, Zhou ZW, Xiao G, Yang YX, Zhang X, Yang T, Chen XW, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Feb 19; 9():1555-84. PubMed ID: 25792811
    [Abstract] [Full Text] [Related]

  • 18. HMGB1/PI3K/Akt/mTOR Signaling Participates in the Pathological Process of Acute Lung Injury by Regulating the Maturation and Function of Dendritic Cells.
    Li R, Zou X, Huang H, Yu Y, Zhang H, Liu P, Pan S, Ouyang Y, Shang Y.
    Front Immunol; 2020 Feb 19; 11():1104. PubMed ID: 32636835
    [Abstract] [Full Text] [Related]

  • 19. Opposite effects of Ha-Ras and Ki-Ras on radiation-induced apoptosis via differential activation of PI3K/Akt and Rac/p38 mitogen-activated protein kinase signaling pathways.
    Choi JA, Park MT, Kang CM, Um HD, Bae S, Lee KH, Kim TH, Kim JH, Cho CK, Lee YS, Chung HY, Lee SJ.
    Oncogene; 2004 Jan 08; 23(1):9-20. PubMed ID: 14712206
    [Abstract] [Full Text] [Related]

  • 20. PI3K/AKT/mTOR Signaling Regulates the Virus/Host Cell Crosstalk in HPV-Positive Cervical Cancer Cells.
    Bossler F, Hoppe-Seyler K, Hoppe-Seyler F.
    Int J Mol Sci; 2019 May 03; 20(9):. PubMed ID: 31058807
    [Abstract] [Full Text] [Related]

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