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389 related items for PubMed ID: 24825125

  • 1. Through-vial impedance spectroscopy of critical events during the freezing stage of the lyophilization cycle: the example of the impact of sucrose on the crystallization of mannitol.
    Arshad MS, Smith G, Polygalov E, Ermolina I.
    Eur J Pharm Biopharm; 2014 Aug; 87(3):598-605. PubMed ID: 24825125
    [Abstract] [Full Text] [Related]

  • 2. Impact of freezing procedure and annealing on the physico-chemical properties and the formation of mannitol hydrate in mannitol-sucrose-NaCl formulations.
    Hawe A, Friess W.
    Eur J Pharm Biopharm; 2006 Nov; 64(3):316-25. PubMed ID: 16875806
    [Abstract] [Full Text] [Related]

  • 3. Effect of cyclophosphamide on the solid form of mannitol during lyophilization.
    Patel K, Munjal B, Bansal AK.
    Eur J Pharm Sci; 2017 Apr 01; 101():251-257. PubMed ID: 28214546
    [Abstract] [Full Text] [Related]

  • 4. Use of subambient differential scanning calorimetry to monitor the frozen-state behavior of blends of excipients for freeze-drying.
    Martini A, Kume S, Crivellente M, Artico R.
    PDA J Pharm Sci Technol; 1997 Apr 01; 51(2):62-7. PubMed ID: 9146035
    [Abstract] [Full Text] [Related]

  • 5. An application for impedance spectroscopy in the characterisation of the glass transition during the lyophilization cycle: the example of a 10% w/v maltodextrin solution.
    Smith G, Arshad MS, Polygalov E, Ermolina I.
    Eur J Pharm Biopharm; 2013 Nov 01; 85(3 Pt B):1130-40. PubMed ID: 23959072
    [Abstract] [Full Text] [Related]

  • 6. Impact of fast and conservative freeze-drying on product quality of protein-mannitol-sucrose-glycerol lyophilizates.
    Horn J, Schanda J, Friess W.
    Eur J Pharm Biopharm; 2018 Jun 01; 127():342-354. PubMed ID: 29522899
    [Abstract] [Full Text] [Related]

  • 7. Vial breakage during freeze-drying: crystallization of sodium chloride in sodium chloride-sucrose frozen aqueous solutions.
    Milton N, Gopalrathnam G, Craig GD, Mishra DS, Roy ML, Yu L.
    J Pharm Sci; 2007 Jul 01; 96(7):1848-53. PubMed ID: 17299763
    [Abstract] [Full Text] [Related]

  • 8. An impedance-based process analytical technology for monitoring the lyophilisation process.
    Smith G, Polygalov E, Arshad MS, Page T, Taylor J, Ermolina I.
    Int J Pharm; 2013 Jun 05; 449(1-2):72-83. PubMed ID: 23591008
    [Abstract] [Full Text] [Related]

  • 9. Investigation of freeze/thaw-related quality attributes of a liquid biopharmaceutical formulation: the role of saccharide excipients.
    Zhou R, Schlam RF, Yin S, Gandhi RB, Adams ML.
    PDA J Pharm Sci Technol; 2012 Jun 05; 66(3):221-35. PubMed ID: 22634588
    [Abstract] [Full Text] [Related]

  • 10. Crystallization of mannitol below Tg' during freeze-drying in binary and ternary aqueous systems.
    Pyne A, Surana R, Suryanarayanan R.
    Pharm Res; 2002 Jun 05; 19(6):901-8. PubMed ID: 12134964
    [Abstract] [Full Text] [Related]

  • 11. In-line and real-time process monitoring of a freeze drying process using Raman and NIR spectroscopy as complementary process analytical technology (PAT) tools.
    De Beer TR, Vercruysse P, Burggraeve A, Quinten T, Ouyang J, Zhang X, Vervaet C, Remon JP, Baeyens WR.
    J Pharm Sci; 2009 Sep 05; 98(9):3430-46. PubMed ID: 19130604
    [Abstract] [Full Text] [Related]

  • 12. Formulations of sugars with amino acids or mannitol--influence of concentration ratio on the properties of the freeze-concentrate and the lyophilizate.
    Lueckel B, Bodmer D, Helk B, Leuenberger H.
    Pharm Dev Technol; 1998 Aug 05; 3(3):325-36. PubMed ID: 9742553
    [Abstract] [Full Text] [Related]

  • 13. Effective inhibition of mannitol crystallization in frozen solutions by sodium chloride.
    Telang C, Yu L, Suryanarayanan R.
    Pharm Res; 2003 Apr 05; 20(4):660-7. PubMed ID: 12739776
    [Abstract] [Full Text] [Related]

  • 14. Vial breakage by frozen mannitol solutions: correlation with thermal characteristics and effect of stereoisomerism, additives, and vial configuration.
    Williams NA, Dean T.
    J Parenter Sci Technol; 1991 Apr 05; 45(2):94-100. PubMed ID: 1904931
    [Abstract] [Full Text] [Related]

  • 15. Process Analytical Technology in Freeze-Drying: Detection of the Secondary Solute + Water Crystallization with Heat Flux Sensors.
    Wang Q, Shalaev E.
    AAPS PharmSciTech; 2018 Apr 05; 19(3):1477-1482. PubMed ID: 29101534
    [Abstract] [Full Text] [Related]

  • 16. Mechanistic studies of glass vial breakage for frozen formulations. I. Vial breakage caused by crystallizable excipient mannitol.
    Jiang G, Akers M, Jain M, Guo J, Distler A, Swift R, Wadhwa MV, Jameel F, Patro S, Freund E.
    PDA J Pharm Sci Technol; 2007 Apr 05; 61(6):441-51. PubMed ID: 18410045
    [Abstract] [Full Text] [Related]

  • 17. Controlled nucleation in freeze-drying: effects on pore size in the dried product layer, mass transfer resistance, and primary drying rate.
    Konstantinidis AK, Kuu W, Otten L, Nail SL, Sever RR.
    J Pharm Sci; 2011 Aug 05; 100(8):3453-3470. PubMed ID: 21465488
    [Abstract] [Full Text] [Related]

  • 18. Controlling the physical form of mannitol in freeze-dried systems.
    Mehta M, Bhardwaj SP, Suryanarayanan R.
    Eur J Pharm Biopharm; 2013 Oct 05; 85(2):207-13. PubMed ID: 23643784
    [Abstract] [Full Text] [Related]

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