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Journal Abstract Search

185 related items for PubMed ID: 24828090

  • 1. Antibacterial inhibitors of Gram-positive thymidylate kinase: structure-activity relationships and chiral preference of a new hydrophobic binding region.
    Kawatkar SP, Keating TA, Olivier NB, Breen JN, Green OM, Guler SY, Hentemann MF, Loch JT, McKenzie AR, Newman JV, Otterson LG, Martínez-Botella G.
    J Med Chem; 2014 Jun 12; 57(11):4584-97. PubMed ID: 24828090
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  • 2. Sulfonylpiperidines as novel, antibacterial inhibitors of Gram-positive thymidylate kinase (TMK).
    Martínez-Botella G, Loch JT, Green OM, Kawatkar SP, Olivier NB, Boriack-Sjodin PA, Keating TA.
    Bioorg Med Chem Lett; 2013 Jan 01; 23(1):169-73. PubMed ID: 23206863
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  • 4. Discovery of selective and potent inhibitors of gram-positive bacterial thymidylate kinase (TMK).
    Martínez-Botella G, Breen JN, Duffy JE, Dumas J, Geng B, Gowers IK, Green OM, Guler S, Hentemann MF, Hernandez-Juan FA, Joseph-McCarthy D, Kawatkar S, Larsen NA, Lazari O, Loch JT, Macritchie JA, McKenzie AR, Newman JV, Olivier NB, Otterson LG, Owens AP, Read J, Sheppard DW, Keating TA.
    J Med Chem; 2012 Nov 26; 55(22):10010-21. PubMed ID: 23043329
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  • 5. Discovery of (3S)-amino-(4R)-ethylpiperidinyl quinolones as potent antibacterial agents with a broad spectrum of activity and activity against resistant pathogens.
    Hu XE, Kim NK, Gray JL, Almstead JI, Seibel WL, Ledoussal B.
    J Med Chem; 2003 Aug 14; 46(17):3655-61. PubMed ID: 12904069
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  • 6. DNA binding ligands targeting drug-resistant bacteria: structure, activity, and pharmacology.
    Kaizerman JA, Gross MI, Ge Y, White S, Hu W, Duan JX, Baird EE, Johnson KW, Tanaka RD, Moser HE, Bürli RW.
    J Med Chem; 2003 Aug 28; 46(18):3914-29. PubMed ID: 12930152
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  • 8. Novel N-linked aminopiperidine inhibitors of bacterial topoisomerase type II: broad-spectrum antibacterial agents with reduced hERG activity.
    Reck F, Alm R, Brassil P, Newman J, Dejonge B, Eyermann CJ, Breault G, Breen J, Comita-Prevoir J, Cronin M, Davis H, Ehmann D, Galullo V, Geng B, Grebe T, Morningstar M, Walker P, Hayter B, Fisher S.
    J Med Chem; 2011 Nov 24; 54(22):7834-47. PubMed ID: 21999508
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  • 9. In-vitro profile of a new beta-lactam, ceftobiprole, with activity against methicillin-resistant Staphylococcus aureus.
    Jones ME.
    Clin Microbiol Infect; 2007 Jun 24; 13 Suppl 2():17-24. PubMed ID: 17488372
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  • 14. Tyrosyl-tRNA synthetase inhibitors as antibacterial agents: synthesis, molecular docking and structure-activity relationship analysis of 3-aryl-4-arylaminofuran-2(5H)-ones.
    Xiao ZP, Ma TW, Liao ML, Feng YT, Peng XC, Li JL, Li ZP, Wu Y, Luo Q, Deng Y, Liang X, Zhu HL.
    Eur J Med Chem; 2011 Oct 24; 46(10):4904-14. PubMed ID: 21856050
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  • 18. New antibacterial agents derived from the DNA gyrase inhibitor cyclothialidine.
    Angehrn P, Buchmann S, Funk C, Goetschi E, Gmuender H, Hebeisen P, Kostrewa D, Link H, Luebbers T, Masciadri R, Nielsen J, Reindl P, Ricklin F, Schmitt-Hoffmann A, Theil FP.
    J Med Chem; 2004 Mar 11; 47(6):1487-513. PubMed ID: 14998336
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  • 20. Identification of phenylisoxazolines as novel and viable antibacterial agents active against Gram-positive pathogens.
    Barbachyn MR, Cleek GJ, Dolak LA, Garmon SA, Morris J, Seest EP, Thomas RC, Toops DS, Watt W, Wishka DG, Ford CW, Zurenko GE, Hamel JC, Schaadt RD, Stapert D, Yagi BH, Adams WJ, Friis JM, Slatter JG, Sams JP, Oien NL, Zaya MJ, Wienkers LC, Wynalda MA.
    J Med Chem; 2003 Jan 16; 46(2):284-302. PubMed ID: 12519066
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