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136 related items for PubMed ID: 2484074

  • 1. New positive inotropic agent OPC-8212 modulates single Ca2+ channels in ventricular myocytes of guinea pig.
    Yatani A, Imoto Y, Schwartz A, Brown AM.
    J Cardiovasc Pharmacol; 1989 Jun; 13(6):812-9. PubMed ID: 2484074
    [Abstract] [Full Text] [Related]

  • 2. Positive inotropic effect of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1 -piperazinyl]-2(1H)-quinolinone (OPC-8212) and mechanism of action in guinea pig ventricular myocardium.
    Takeya K, Yajima M, Kobayashi-Ando S, Ando H.
    Arzneimittelforschung; 1984 Jun; 34(3A):364-70. PubMed ID: 6331466
    [Abstract] [Full Text] [Related]

  • 3. Identification of cardiotonic sodium channel activators by potassium depolarization in isolated guinea-pig atria.
    Berthold H, Scholtysik G, Schaad A.
    J Pharmacol Methods; 1990 Sep; 24(2):121-35. PubMed ID: 1700227
    [Abstract] [Full Text] [Related]

  • 4. Effects of new inotropic agents on cyclic nucleotide metabolism and calcium transients in canine ventricular muscle.
    Endoh M, Yanagisawa T, Taira N, Blinks JR.
    Circulation; 1986 Mar; 73(3 Pt 2):III117-33. PubMed ID: 2417745
    [Abstract] [Full Text] [Related]

  • 5. A dihydropyridine (Bay k 8644) that enhances calcium currents in guinea pig and calf myocardial cells. A new type of positive inotropic agent.
    Thomas G, Chung M, Cohen CJ.
    Circ Res; 1985 Jan; 56(1):87-96. PubMed ID: 2578336
    [Abstract] [Full Text] [Related]

  • 6. Ionic basis for OPC-8212-induced increase in action potential duration in isolated rabbit, guinea pig and human ventricular myocytes.
    Lathrop DA, Nánási PP, Schwartz A, Varró A.
    Eur J Pharmacol; 1993 Aug 24; 240(2-3):127-37. PubMed ID: 8243533
    [Abstract] [Full Text] [Related]

  • 7. Involvement of cyclic AMP in the positive inotropic effect of OPC-8212, a new cardiotonic agent, on the canine ventricular muscle.
    Yanagisawa T, Endoh M, Taira N.
    Jpn J Pharmacol; 1984 Nov 24; 36(3):379-88. PubMed ID: 6097725
    [Abstract] [Full Text] [Related]

  • 8. Cyclic-AMP-dependent phosphorylation modulates the stereospecific activation of cardiac Ca channels by Bay K 8644.
    Tiaho F, Richard S, Lory P, Nerbonne JM, Nargeot J.
    Pflugers Arch; 1990 Sep 24; 417(1):58-66. PubMed ID: 1705699
    [Abstract] [Full Text] [Related]

  • 9. Modulation of manganese currents by 1, 4-dihydropyridines, isoproterenol and forskolin in rabbit ventricular cells.
    Masumiya H, Tsujikawa H, Hino N, Ochi R.
    Pflugers Arch; 2003 Sep 24; 446(6):695-701. PubMed ID: 12827360
    [Abstract] [Full Text] [Related]

  • 10. Effects of a new positive inotropic agent, 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212) and its solvent sulfolane on isolated heart preparations of the rat, guinea pig, and dog.
    Grupp G, Grupp IL, Newman G, Schwartz A.
    Arzneimittelforschung; 1984 Sep 24; 34(3A):359-63. PubMed ID: 6540089
    [Abstract] [Full Text] [Related]

  • 11. Effects of a novel cardiotonic agent (+-)-6-[3-(3,4-dimethoxybenzylamino)-2-hydroxypropoxy]-2(1H)-quinolino ne (OPC-18790) on contractile force, cyclic AMP level, and aequorin light transients in dog ventricular myocardium.
    Endoh M, Kawabata Y, Katano Y, Norota I.
    J Cardiovasc Pharmacol; 1994 May 24; 23(5):723-30. PubMed ID: 7521454
    [Abstract] [Full Text] [Related]

  • 12. Cardiac inotropic responses to calcium and forskolin are not altered by prolonged isoproterenol infusion.
    Bowling N, Wyss VL, Gengo PJ, Utterback B, Kauffman RF, Hayes JS.
    Eur J Pharmacol; 1990 Oct 09; 187(2):155-64. PubMed ID: 1703077
    [Abstract] [Full Text] [Related]

  • 13. Subcellular mechanism of the positive inotropic effect of a new quinolinone derivative OPC-8490 on the dog ventricular myocardium.
    Endoh M, Satoh H, Norota I, Hirano K, Hosokawa T.
    Heart Vessels; 1991 Oct 09; 6(3):158-67. PubMed ID: 1655692
    [Abstract] [Full Text] [Related]

  • 14. Positive inotropic and chronotropic effects of toborinone and its electrophysiological properties in the isolated hearts of rabbits and guinea-pigs.
    Takase H, Orito K, Mori T, Fujiki H, Sekiguchi K, Tominaga M, Iijima T.
    Arzneimittelforschung; 1996 Jun 09; 46(6):579-86. PubMed ID: 8767347
    [Abstract] [Full Text] [Related]

  • 15. Effects of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl] -2(1H)-quinolinone (OPC-8212), a new inotropic agent, on cardiotonic activity and coronary hemodynamics.
    Inoue M, Hori M, Nakajima S, Kitakaze M, Fukunami M, Ishida Y, Abe H.
    Arzneimittelforschung; 1984 Jun 09; 34(3A):355-9. PubMed ID: 6540088
    [Abstract] [Full Text] [Related]

  • 16. Dual effects of dihydropyridines on whole cell and unitary calcium currents in single ventricular cells of guinea-pig.
    Brown AM, Kunze DL, Yatani A.
    J Physiol; 1986 Oct 09; 379():495-514. PubMed ID: 2435896
    [Abstract] [Full Text] [Related]

  • 17. Altered pharmacologic responsiveness of reduced L-type calcium currents in myocytes surviving in the infarcted heart.
    Aggarwal R, Boyden PA.
    J Cardiovasc Electrophysiol; 1996 Jan 09; 7(1):20-35. PubMed ID: 8718981
    [Abstract] [Full Text] [Related]

  • 18. Modulation of calcium channel currents in guinea-pig single ventricular heart cells by the dihydropyridine Bay K 8644.
    Markwardt F, Nilius B.
    J Physiol; 1988 May 09; 399():559-75. PubMed ID: 2457095
    [Abstract] [Full Text] [Related]

  • 19. Mode and mechanism of action of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212), a novel positive inotropic drug, on the dog heart.
    Taira N, Endoh M, Iijima T, Satoh K, Yanagisawa T, Yamashita S, Maruyama M, Kawada M, Morita T, Wada Y.
    Arzneimittelforschung; 1984 May 09; 34(3A):347-55. PubMed ID: 6331465
    [Abstract] [Full Text] [Related]

  • 20. L-type calcium channel activity in human atrial myocytes as influenced by 5-HT.
    Jahnel U, Nawrath H, Rupp J, Ochi R.
    Naunyn Schmiedebergs Arch Pharmacol; 1993 Oct 09; 348(4):396-402. PubMed ID: 7506393
    [Abstract] [Full Text] [Related]

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