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601 related items for PubMed ID: 24844147

  • 1. Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons.
    Richter F, Gao F, Medvedeva V, Lee P, Bove N, Fleming SM, Michaud M, Lemesre V, Patassini S, De La Rosa K, Mulligan CK, Sioshansi PC, Zhu C, Coppola G, Bordet T, Pruss RM, Chesselet MF.
    Neurobiol Dis; 2014 Sep; 69():263-75. PubMed ID: 24844147
    [Abstract] [Full Text] [Related]

  • 2. Region specific mitochondrial impairment in mice with widespread overexpression of alpha-synuclein.
    Subramaniam SR, Vergnes L, Franich NR, Reue K, Chesselet MF.
    Neurobiol Dis; 2014 Oct; 70():204-13. PubMed ID: 25016198
    [Abstract] [Full Text] [Related]

  • 3. Telmisartan attenuates MPTP induced dopaminergic degeneration and motor dysfunction through regulation of α-synuclein and neurotrophic factors (BDNF and GDNF) expression in C57BL/6J mice.
    Sathiya S, Ranju V, Kalaivani P, Priya RJ, Sumathy H, Sunil AG, Babu CS.
    Neuropharmacology; 2013 Oct; 73():98-110. PubMed ID: 23747572
    [Abstract] [Full Text] [Related]

  • 4. AAV1/2-induced overexpression of A53T-α-synuclein in the substantia nigra results in degeneration of the nigrostriatal system with Lewy-like pathology and motor impairment: a new mouse model for Parkinson's disease.
    Ip CW, Klaus LC, Karikari AA, Visanji NP, Brotchie JM, Lang AE, Volkmann J, Koprich JB.
    Acta Neuropathol Commun; 2017 Feb 01; 5(1):11. PubMed ID: 28143577
    [Abstract] [Full Text] [Related]

  • 5. Caffeic acid reduces A53T α-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse model of Parkinson's disease.
    Zhang Y, Wu Q, Zhang L, Wang Q, Yang Z, Liu J, Feng L.
    Pharmacol Res; 2019 Dec 01; 150():104538. PubMed ID: 31707034
    [Abstract] [Full Text] [Related]

  • 6. Cyclosporine A and MnTMPyP Alleviate α-Synuclein Expression and Aggregation in Cypermethrin-Induced Parkinsonism.
    Agrawal S, Dixit A, Singh A, Tripathi P, Singh D, Patel DK, Singh MP.
    Mol Neurobiol; 2015 Dec 01; 52(3):1619-1628. PubMed ID: 25370934
    [Abstract] [Full Text] [Related]

  • 7. Manganese exposure exacerbates progressive motor deficits and neurodegeneration in the MitoPark mouse model of Parkinson's disease: Relevance to gene and environment interactions in metal neurotoxicity.
    Langley MR, Ghaisas S, Ay M, Luo J, Palanisamy BN, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG.
    Neurotoxicology; 2018 Jan 01; 64():240-255. PubMed ID: 28595911
    [Abstract] [Full Text] [Related]

  • 8. Overexpression of parkin ameliorates dopaminergic neurodegeneration induced by 1- methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
    Bian M, Liu J, Hong X, Yu M, Huang Y, Sheng Z, Fei J, Huang F.
    PLoS One; 2012 Jan 01; 7(6):e39953. PubMed ID: 22792139
    [Abstract] [Full Text] [Related]

  • 9. Monoamine Oxidase-B Inhibition Facilitates α-Synuclein Secretion In Vitro and Delays Its Aggregation in rAAV-Based Rat Models of Parkinson's Disease.
    Nakamura Y, Arawaka S, Sato H, Sasaki A, Shigekiyo T, Takahata K, Tsunekawa H, Kato T.
    J Neurosci; 2021 Sep 01; 41(35):7479-7491. PubMed ID: 34290084
    [Abstract] [Full Text] [Related]

  • 10. Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson's disease model.
    Wegrzynowicz M, Bar-On D, Calo' L, Anichtchik O, Iovino M, Xia J, Ryazanov S, Leonov A, Giese A, Dalley JW, Griesinger C, Ashery U, Spillantini MG.
    Acta Neuropathol; 2019 Oct 01; 138(4):575-595. PubMed ID: 31165254
    [Abstract] [Full Text] [Related]

  • 11. α-Synuclein-induced dopaminergic neurodegeneration in a rat model of Parkinson's disease occurs independent of ATP13A2 (PARK9).
    Daniel G, Musso A, Tsika E, Fiser A, Glauser L, Pletnikova O, Schneider BL, Moore DJ.
    Neurobiol Dis; 2015 Jan 01; 73():229-43. PubMed ID: 25461191
    [Abstract] [Full Text] [Related]

  • 12. Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease.
    Frahm S, Melis V, Horsley D, Rickard JE, Riedel G, Fadda P, Scherma M, Harrington CR, Wischik CM, Theuring F, Schwab K.
    Behav Brain Res; 2018 Feb 26; 339():153-168. PubMed ID: 29180135
    [Abstract] [Full Text] [Related]

  • 13. Tea polyphenols alleviate motor impairments, dopaminergic neuronal injury, and cerebral α-synuclein aggregation in MPTP-intoxicated parkinsonian monkeys.
    Chen M, Wang T, Yue F, Li X, Wang P, Li Y, Chan P, Yu S.
    Neuroscience; 2015 Feb 12; 286():383-92. PubMed ID: 25498223
    [Abstract] [Full Text] [Related]

  • 14. Behavioral effects of dopaminergic agonists in transgenic mice overexpressing human wildtype alpha-synuclein.
    Fleming SM, Salcedo J, Hutson CB, Rockenstein E, Masliah E, Levine MS, Chesselet MF.
    Neuroscience; 2006 Nov 03; 142(4):1245-53. PubMed ID: 16934409
    [Abstract] [Full Text] [Related]

  • 15. Mutant α-Synuclein Overexpression Induces Stressless Pacemaking in Vagal Motoneurons at Risk in Parkinson's Disease.
    Lasser-Katz E, Simchovitz A, Chiu WH, Oertel WH, Sharon R, Soreq H, Roeper J, Goldberg JA.
    J Neurosci; 2017 Jan 04; 37(1):47-57. PubMed ID: 28053029
    [Abstract] [Full Text] [Related]

  • 16. Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice.
    Longo F, Mercatelli D, Novello S, Arcuri L, Brugnoli A, Vincenzi F, Russo I, Berti G, Mabrouk OS, Kennedy RT, Shimshek DR, Varani K, Bubacco L, Greggio E, Morari M.
    Acta Neuropathol Commun; 2017 Mar 14; 5(1):22. PubMed ID: 28292328
    [Abstract] [Full Text] [Related]

  • 17. Neuroprotective effects of osmotin in Parkinson's disease-associated pathology via the AdipoR1/MAPK/AMPK/mTOR signaling pathways.
    Park JS, Choe K, Lee HJ, Park TJ, Kim MO.
    J Biomed Sci; 2023 Aug 11; 30(1):66. PubMed ID: 37568205
    [Abstract] [Full Text] [Related]

  • 18. Reprint of: revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abuse.
    Perfeito R, Cunha-Oliveira T, Rego AC.
    Free Radic Biol Med; 2013 Sep 11; 62():186-201. PubMed ID: 23743292
    [Abstract] [Full Text] [Related]

  • 19. Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of α-synuclein in Parkinson's disease models.
    Hebron ML, Lonskaya I, Moussa CE.
    Hum Mol Genet; 2013 Aug 15; 22(16):3315-28. PubMed ID: 23666528
    [Abstract] [Full Text] [Related]

  • 20. Soluble Epoxide Hydrolase Inhibition Attenuates MPTP-Induced Neurotoxicity in the Nigrostriatal Dopaminergic System: Involvement of α-Synuclein Aggregation and ER Stress.
    Huang HJ, Wang YT, Lin HC, Lee YH, Lin AM.
    Mol Neurobiol; 2018 Jan 15; 55(1):138-144. PubMed ID: 28822080
    [Abstract] [Full Text] [Related]

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