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257 related items for PubMed ID: 24853400
1. Expression of CYP3A in chronic ethanol-fed mice is mediated by endogenous pregnane X receptor ligands formed by enhanced cholesterol metabolism. Je YT, Sim WC, Kim DG, Jung BH, Shin HS, Lee BH. Arch Toxicol; 2015 Apr; 89(4):579-89. PubMed ID: 24853400 [Abstract] [Full Text] [Related]
2. Chronic ethanol exposure downregulates hepatic expression of pregnane X receptor and P450 3A11 in female ICR mice. Wang JP, Xu DX, Sun MF, Chen YH, Wang H, Wei W. Toxicology; 2005 Nov 15; 215(3):234-44. PubMed ID: 16126318 [Abstract] [Full Text] [Related]
3. Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance. Dussault I, Yoo HD, Lin M, Wang E, Fan M, Batta AK, Salen G, Erickson SK, Forman BM. Proc Natl Acad Sci U S A; 2003 Feb 04; 100(3):833-8. PubMed ID: 12569201 [Abstract] [Full Text] [Related]
4. Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor. Goodwin B, Gauthier KC, Umetani M, Watson MA, Lochansky MI, Collins JL, Leitersdorf E, Mangelsdorf DJ, Kliewer SA, Repa JJ. Proc Natl Acad Sci U S A; 2003 Jan 07; 100(1):223-8. PubMed ID: 12509506 [Abstract] [Full Text] [Related]
5. Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3a in mouse liver. Xu DX, Wei W, Sun MF, Wu CY, Wang JP, Wei LZ, Zhou CF. Free Radic Biol Med; 2004 Jul 01; 37(1):10-22. PubMed ID: 15183191 [Abstract] [Full Text] [Related]
6. Pregnane X receptor mediated-transcription regulation of CYP3A by glycyrrhizin: a possible mechanism for its hepatoprotective property against lithocholic acid-induced injury. Wang YG, Zhou JM, Ma ZC, Li H, Liang QD, Tan HL, Xiao CR, Zhang BL, Gao Y. Chem Biol Interact; 2012 Oct 25; 200(1):11-20. PubMed ID: 22982774 [Abstract] [Full Text] [Related]
7. Perinatal lipopolysaccharide exposure downregulates pregnane X receptor and Cyp3a11 expression in fetal mouse liver. Xu DX, Chen YH, Wang JP, Sun MF, Wang H, Wei LZ, Wei W. Toxicol Sci; 2005 Sep 25; 87(1):38-45. PubMed ID: 15976188 [Abstract] [Full Text] [Related]
8. Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes. Roth A, Looser R, Kaufmann M, Meyer UA. Pharmacogenet Genomics; 2008 Apr 25; 18(4):325-37. PubMed ID: 18334917 [Abstract] [Full Text] [Related]
9. Indirect activation of pregnane X receptor in the induction of hepatic CYP3A11 by high-dose rifampicin in mice. Yamasaki Y, Kobayashi K, Inaba A, Uehara D, Tojima H, Kakizaki S, Chiba K. Xenobiotica; 2018 Nov 25; 48(11):1098-1105. PubMed ID: 29095659 [Abstract] [Full Text] [Related]
10. Lipopolysaccharide downregulates the expressions of intestinal pregnane X receptor and cytochrome P450 3a11. Xu DX, Wang JP, Sun MF, Chen YH, Wei W. Eur J Pharmacol; 2006 Apr 24; 536(1-2):162-70. PubMed ID: 16556443 [Abstract] [Full Text] [Related]
11. Gastrectomy increases the expression of hepatic cytochrome P450 3A by increasing lithocholic acid-producing enteric bacteria in mice. Ishii M, Toda T, Ikarashi N, Kusunoki Y, Kon R, Ochiai W, Machida Y, Sugiyama K. Biol Pharm Bull; 2014 Apr 24; 37(2):298-305. PubMed ID: 24270587 [Abstract] [Full Text] [Related]
12. The involvement of the pregnane X receptor in hepatic gene regulation during inflammation in mice. Teng S, Piquette-Miller M. J Pharmacol Exp Ther; 2005 Feb 24; 312(2):841-8. PubMed ID: 15456840 [Abstract] [Full Text] [Related]
13. Lipopolysaccharide treatment downregulates the expression of the pregnane X receptor, cyp3a11 and mdr1a genes in mouse placenta. Chen YH, Wang JP, Wang H, Sun MF, Wei LZ, Wei W, Xu DX. Toxicology; 2005 Aug 01; 211(3):242-52. PubMed ID: 15869837 [Abstract] [Full Text] [Related]
14. The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. Staudinger JL, Goodwin B, Jones SA, Hawkins-Brown D, MacKenzie KI, LaTour A, Liu Y, Klaassen CD, Brown KK, Reinhard J, Willson TM, Koller BH, Kliewer SA. Proc Natl Acad Sci U S A; 2001 Mar 13; 98(6):3369-74. PubMed ID: 11248085 [Abstract] [Full Text] [Related]
15. Hepatoprotective role of PXR activation and MRP3 in cholic acid-induced cholestasis. Teng S, Piquette-Miller M. Br J Pharmacol; 2007 Jun 13; 151(3):367-76. PubMed ID: 17435798 [Abstract] [Full Text] [Related]
16. Coordinated roles of pregnane X receptor and constitutive androstane receptor in autoinduction of voriconazole metabolism in mice. Ohbuchi M, Yoshinari K, Kaneko H, Matsumoto S, Inoue A, Kawamura A, Usui T, Yamazoe Y. Antimicrob Agents Chemother; 2013 Mar 13; 57(3):1332-8. PubMed ID: 23274663 [Abstract] [Full Text] [Related]
17. CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice. Wagner M, Halilbasic E, Marschall HU, Zollner G, Fickert P, Langner C, Zatloukal K, Denk H, Trauner M. Hepatology; 2005 Aug 13; 42(2):420-30. PubMed ID: 15986414 [Abstract] [Full Text] [Related]
18. Interactions of pharmaceuticals and other xenobiotics on hepatic pregnane X receptor and cytochrome P450 3A signaling pathway in rainbow trout (Oncorhynchus mykiss). Wassmur B, Gräns J, Kling P, Celander MC. Aquat Toxicol; 2010 Oct 01; 100(1):91-100. PubMed ID: 20719396 [Abstract] [Full Text] [Related]
19. Melatonin attenuates lipopolysaccharide-induced down-regulation of pregnane X receptor and its target gene CYP3A in mouse liver. Xu DX, Wei W, Sun MF, Wei LZ, Wang JP. J Pineal Res; 2005 Jan 01; 38(1):27-34. PubMed ID: 15617534 [Abstract] [Full Text] [Related]
20. Intestinal detoxification limits the activation of hepatic pregnane X receptor by lithocholic acid. Owen BM, Milona A, van Mil S, Clements P, Holder J, Boudjelal M, Cairns W, Parker M, White R, Williamson C. Drug Metab Dispos; 2010 Jan 01; 38(1):143-9. PubMed ID: 19797606 [Abstract] [Full Text] [Related] Page: [Next] [New Search]