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119 related items for PubMed ID: 24859271

  • 1. Investigation of maternal and fetal exposure to an IgG2 monoclonal antibody following biweekly intravaginal administration to cynomolgus monkeys throughout pregnancy.
    Moffat GJ, Davies R, Kwon G, Retter MW, Chellman GJ, Kanapuram S, Moore M, Loomis M, Wang W, Pyrah IT.
    Reprod Toxicol; 2014 Sep; 48():132-7. PubMed ID: 24859271
    [Abstract] [Full Text] [Related]

  • 2. Placental transfer of a fully human IgG2 monoclonal antibody in the cynomolgus monkey, rat, and rabbit: a comparative assessment from during organogenesis to late gestation.
    Moffat GJ, Retter MW, Kwon G, Loomis M, Hock MB, Hall C, Bussiere J, Lewis EM, Chellman GJ.
    Birth Defects Res B Dev Reprod Toxicol; 2014 Apr; 101(2):178-88. PubMed ID: 24753333
    [Abstract] [Full Text] [Related]

  • 3. Assessment of fetal exposure risk following seminal excretion of a therapeutic IgG4 (T-IgG4) monoclonal antibody using a rabbit model.
    Breslin WJ, Hilbish KG, Page TJ, Coutant DE.
    Reprod Toxicol; 2014 Sep; 48():124-31. PubMed ID: 24863471
    [Abstract] [Full Text] [Related]

  • 4. An Enhanced Pre- and Postnatal Development Study in Cynomolgus Monkeys with Tabalumab: A Human IgG4 Monoclonal Antibody.
    Breslin WJ, Hilbish KG, Martin JA, Halstead CA, Newcomb DL, Chellman GJ.
    Birth Defects Res B Dev Reprod Toxicol; 2015 Jun; 104(3):100-16. PubMed ID: 26195230
    [Abstract] [Full Text] [Related]

  • 5. Placental transfer of Fc-containing biopharmaceuticals across species, an industry survey analysis.
    Bowman CJ, Breslin WJ, Connor AV, Martin PL, Moffat GJ, Sivaraman L, Tornesi MB, Chivers S.
    Birth Defects Res B Dev Reprod Toxicol; 2013 Dec; 98(6):459-85. PubMed ID: 24391099
    [Abstract] [Full Text] [Related]

  • 6. Developmental immunotoxicology assessment of rituximab in cynomolgus monkeys.
    Vaidyanathan A, McKeever K, Anand B, Eppler S, Weinbauer GF, Beyer JC.
    Toxicol Sci; 2011 Jan; 119(1):116-25. PubMed ID: 20937725
    [Abstract] [Full Text] [Related]

  • 7. Pre- and postnatal development in the cynomolgus monkey following administration of ABT-874, a human anti-IL-12/23p40 monoclonal antibody.
    Enright BP, Tornesi B, Weinbauer GF, Blaich G.
    Birth Defects Res B Dev Reprod Toxicol; 2012 Dec; 95(6):431-43. PubMed ID: 23212752
    [Abstract] [Full Text] [Related]

  • 8. Evaluation of early fetal exposure to vaginally-administered metronidazole in pregnant cynomolgus monkeys.
    Thompson KE, Newcomb DL, Moffat GJ, Zalikowski J, Chellman GJ, McNerney ME.
    Reprod Toxicol; 2016 Jan; 59():17-21. PubMed ID: 26524246
    [Abstract] [Full Text] [Related]

  • 9. Retinoid metabolism and transplacental pharmacokinetics in the cynomolgus monkey following a nonteratogenic dosing regimen with all-trans-retinoic acid.
    Tzimas G, Nau H, Hendrickx AG, Peterson PE, Hummler H.
    Teratology; 1996 Nov; 54(5):255-65. PubMed ID: 9035347
    [Abstract] [Full Text] [Related]

  • 10. Embryo-fetal developmental toxicity of figitumumab, an anti-insulin-like growth factor-1 receptor (IGF-1R) monoclonal antibody, in cynomolgus monkeys.
    Bowman CJ, Chmielewski G, Oneda S, Finco D, Boucher MA, Todd M.
    Birth Defects Res B Dev Reprod Toxicol; 2010 Aug; 89(4):326-38. PubMed ID: 20540090
    [Abstract] [Full Text] [Related]

  • 11. Embryo-fetal distribution of a biopharmaceutical IgG2 during rat organogenesis.
    Bowman CJ, King LE, Stedman DB.
    Reprod Toxicol; 2012 Aug; 34(1):66-72. PubMed ID: 22543284
    [Abstract] [Full Text] [Related]

  • 12. Quantitative determination of humanized monoclonal antibody rhuMAb2H7 in cynomolgus monkey serum using a Generic Immunoglobulin Pharmacokinetic (GRIP) assay.
    Yang J, Ng C, Lowman H, Chestnut R, Schofield C, Sandlund B, Ernst J, Bennett G, Quarmby V.
    J Immunol Methods; 2008 Jun 01; 335(1-2):8-20. PubMed ID: 18402977
    [Abstract] [Full Text] [Related]

  • 13. Pharmacokinetics of humanized monoclonal anti-tumor necrosis factor-{alpha} antibody and its neonatal Fc receptor variants in mice and cynomolgus monkeys.
    Deng R, Loyet KM, Lien S, Iyer S, DeForge LE, Theil FP, Lowman HB, Fielder PJ, Prabhu S.
    Drug Metab Dispos; 2010 Apr 01; 38(4):600-5. PubMed ID: 20071453
    [Abstract] [Full Text] [Related]

  • 14. Placental and Fetal Effects of Onartuzumab, a Met/HGF Signaling Antagonist, When Administered to Pregnant Cynomolgus Monkeys.
    Prell RA, Dybdal N, Arima A, Chihaya Y, Nijem I, Halpern W.
    Toxicol Sci; 2018 Sep 01; 165(1):186-197. PubMed ID: 29893934
    [Abstract] [Full Text] [Related]

  • 15. An interspecies comparison of placental antibody transfer: new insights into developmental toxicity testing of monoclonal antibodies.
    Pentsuk N, van der Laan JW.
    Birth Defects Res B Dev Reprod Toxicol; 2009 Aug 01; 86(4):328-44. PubMed ID: 19626656
    [Abstract] [Full Text] [Related]

  • 16. Placental transfer of 125 iodinated humanized immunoglobulin G2Δa in the cynomolgus monkey.
    Catlin NR, Mitchell AZ, Potchoiba MJ, O'Hara DM, Wang M, Zhang M, Weinbauer GF, Bowman CJ.
    Birth Defects Res; 2020 Jan 01; 112(1):105-117. PubMed ID: 31746560
    [Abstract] [Full Text] [Related]

  • 17. Embryo-fetal exposure and developmental outcome of thalidomide following oral and intravaginal administration to pregnant rabbits.
    Hui JY, Hoffmann M, Kumar G.
    Reprod Toxicol; 2014 Sep 01; 48():115-23. PubMed ID: 24859269
    [Abstract] [Full Text] [Related]

  • 18. Developmental and peri-postnatal study in cynomolgus monkeys with belimumab, a monoclonal antibody directed against B-lymphocyte stimulator.
    Auyeung-Kim DJ, Devalaraja MN, Migone TS, Cai W, Chellman GJ.
    Reprod Toxicol; 2009 Dec 01; 28(4):443-55. PubMed ID: 19631735
    [Abstract] [Full Text] [Related]

  • 19. Embryotoxicity studies of norfloxacin in cynomolgus monkeys: I. Teratology studies and norfloxacin plasma concentration in pregnant and nonpregnant monkeys.
    Cukierski MA, Prahalada S, Zacchei AG, Peter CP, Rodgers JD, Hess DL, Cukierski MJ, Tarantal AF, Nyland T, Robertson RT.
    Teratology; 1989 Jan 01; 39(1):39-52. PubMed ID: 2718139
    [Abstract] [Full Text] [Related]

  • 20. Reprint of "Potential seminal transport of pharmaceuticals to the conceptus".
    Scialli AR, Bailey G, Beyer BK, Bøgh IB, Breslin WJ, Chen CL, DeLise AM, Hui JY, Moffat GJ, Stewart J, Thompson KE.
    Reprod Toxicol; 2016 Jan 01; 59():22-30. PubMed ID: 26854737
    [Abstract] [Full Text] [Related]

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