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360 related items for PubMed ID: 24866585

  • 1. YM155 sensitizes triple-negative breast cancer to membrane-bound TRAIL through p38 MAPK- and CHOP-mediated DR5 upregulation.
    Pennati M, Sbarra S, De Cesare M, Lopergolo A, Locatelli SL, Campi E, Daidone MG, Carlo-Stella C, Gianni AM, Zaffaroni N.
    Int J Cancer; 2015 Jan 15; 136(2):299-309. PubMed ID: 24866585
    [Abstract] [Full Text] [Related]

  • 2. Caudatin potentiates the anti-tumor effects of TRAIL against human breast cancer by upregulating DR5.
    Fei HR, Yuan C, Wang GL, Zhao Y, Li ZJ, Du X, Wang FZ.
    Phytomedicine; 2019 Sep 15; 62():152950. PubMed ID: 31102888
    [Abstract] [Full Text] [Related]

  • 3. Small molecule inhibitor YM155-mediated activation of death receptor 5 is crucial for chemotherapy-induced apoptosis in pancreatic carcinoma.
    Zhao X, Puszyk WM, Lu Z, Ostrov DA, George TJ, Robertson KD, Liu C.
    Mol Cancer Ther; 2015 Jan 15; 14(1):80-9. PubMed ID: 25344582
    [Abstract] [Full Text] [Related]

  • 4. Etoposide and doxorubicin enhance the sensitivity of triple negative breast cancers through modulation of TRAIL-DR5 axis.
    Das S, Tripathi N, Siddharth S, Nayak A, Nayak D, Sethy C, Bharatam PV, Kundu CN.
    Apoptosis; 2017 Oct 15; 22(10):1205-1224. PubMed ID: 28702823
    [Abstract] [Full Text] [Related]

  • 5. Quercetin enhances apoptotic effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in ovarian cancer cells through reactive oxygen species (ROS) mediated CCAAT enhancer-binding protein homologous protein (CHOP)-death receptor 5 pathway.
    Yi L, Zongyuan Y, Cheng G, Lingyun Z, Guilian Y, Wei G.
    Cancer Sci; 2014 May 15; 105(5):520-7. PubMed ID: 24612139
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of euchromatin histone-lysine N-methyltransferase 2 sensitizes breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through reactive oxygen species-mediated activating transcription factor 4-C/EBP homologous protein-death receptor 5 pathway activation.
    Kim SY, Hong M, Heo SH, Park S, Kwon TK, Sung YH, Oh Y, Lee S, Yi GS, Kim I.
    Mol Carcinog; 2018 Nov 15; 57(11):1492-1506. PubMed ID: 29964331
    [Abstract] [Full Text] [Related]

  • 7. Synergistic antitumor activities of sepantronium bromide (YM155), a survivin suppressant, in combination with microtubule-targeting agents in triple-negative breast cancer cells.
    Kaneko N, Yamanaka K, Kita A, Tabata K, Akabane T, Mori M.
    Biol Pharm Bull; 2013 Nov 15; 36(12):1921-7. PubMed ID: 24432379
    [Abstract] [Full Text] [Related]

  • 8. Pterostilbene Enhances TRAIL-Induced Apoptosis through the Induction of Death Receptors and Downregulation of Cell Survival Proteins in TRAIL-Resistance Triple Negative Breast Cancer Cells.
    Hung CM, Liu LC, Ho CT, Lin YC, Way TD.
    J Agric Food Chem; 2017 Dec 27; 65(51):11179-11191. PubMed ID: 29164887
    [Abstract] [Full Text] [Related]

  • 9. YM155, a selective survivin suppressant, inhibits tumor spread and prolongs survival in a spontaneous metastatic model of human triple negative breast cancer.
    Yamanaka K, Nakata M, Kaneko N, Fushiki H, Kita A, Nakahara T, Koutoku H, Sasamata M.
    Int J Oncol; 2011 Sep 27; 39(3):569-75. PubMed ID: 21674125
    [Abstract] [Full Text] [Related]

  • 10. YM155 sensitizes TRAIL-induced apoptosis through cathepsin S-dependent down-regulation of Mcl-1 and NF-κB-mediated down-regulation of c-FLIP expression in human renal carcinoma Caki cells.
    Woo SM, Min KJ, Seo BR, Kwon TK.
    Oncotarget; 2016 Sep 20; 7(38):61520-61532. PubMed ID: 27528031
    [Abstract] [Full Text] [Related]

  • 11. Antitumor activity of YM155, a selective small-molecule survivin suppressant, alone and in combination with docetaxel in human malignant melanoma models.
    Yamanaka K, Nakahara T, Yamauchi T, Kita A, Takeuchi M, Kiyonaga F, Kaneko N, Sasamata M.
    Clin Cancer Res; 2011 Aug 15; 17(16):5423-31. PubMed ID: 21737502
    [Abstract] [Full Text] [Related]

  • 12. Indomethacin sensitizes TRAIL-resistant melanoma cells to TRAIL-induced apoptosis through ROS-mediated upregulation of death receptor 5 and downregulation of survivin.
    Tse AK, Cao HH, Cheng CY, Kwan HY, Yu H, Fong WF, Yu ZL.
    J Invest Dermatol; 2014 May 15; 134(5):1397-1407. PubMed ID: 24213373
    [Abstract] [Full Text] [Related]

  • 13. Licochalcone D exhibits cytotoxicity in breast cancer cells and enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis through upregulation of death receptor 5.
    Zhang Y, Wang L, Dong C, Zhuang Y, Hao G, Wang F.
    J Biochem Mol Toxicol; 2024 Jul 15; 38(7):e23757. PubMed ID: 38937960
    [Abstract] [Full Text] [Related]

  • 14. Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL.
    Sung B, Ravindran J, Prasad S, Pandey MK, Aggarwal BB.
    J Biol Chem; 2010 Nov 12; 285(46):35418-27. PubMed ID: 20837473
    [Abstract] [Full Text] [Related]

  • 15. Cyclopamine sensitizes TRAIL-resistant gastric cancer cells to TRAIL-induced apoptosis via endoplasmic reticulum stress-mediated increase of death receptor 5 and survivin degradation.
    Na YJ, Lee DH, Kim JL, Kim BR, Park SH, Jo MJ, Jeong S, Kim HJ, Lee SY, Jeong YA, Oh SC.
    Int J Biochem Cell Biol; 2017 Aug 12; 89():147-156. PubMed ID: 28624529
    [Abstract] [Full Text] [Related]

  • 16. CSC-3436 sensitizes triple negative breast cancer cells to TRAIL-induced apoptosis through ROS-mediated p38/CHOP/death receptor 5 signaling pathways.
    Huang CC, Cheng YC, Lin YC, Chou CH, Ho CT, Wang HK, Way TD.
    Environ Toxicol; 2021 Dec 12; 36(12):2578-2588. PubMed ID: 34599545
    [Abstract] [Full Text] [Related]

  • 17. Kaempferol Sensitizes Human Ovarian Cancer Cells-OVCAR-3 and SKOV-3 to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)-Induced Apoptosis via JNK/ERK-CHOP Pathway and Up-Regulation of Death Receptors 4 and 5.
    Zhao Y, Tian B, Wang Y, Ding H.
    Med Sci Monit; 2017 Oct 26; 23():5096-5105. PubMed ID: 29070784
    [Abstract] [Full Text] [Related]

  • 18. Amiodarone sensitizes human glioma cells but not astrocytes to TRAIL-induced apoptosis via CHOP-mediated DR5 upregulation.
    Kim IY, Kang YJ, Yoon MJ, Kim EH, Kim SU, Kwon TK, Kim IA, Choi KS.
    Neuro Oncol; 2011 Mar 26; 13(3):267-79. PubMed ID: 21292685
    [Abstract] [Full Text] [Related]

  • 19. Tanshinone IIA Facilitates TRAIL Sensitization by Up-regulating DR5 through the ROS-JNK-CHOP Signaling Axis in Human Ovarian Carcinoma Cell Lines.
    Chang CC, Kuan CP, Lin JY, Lai JS, Ho TF.
    Chem Res Toxicol; 2015 Aug 17; 28(8):1574-83. PubMed ID: 26203587
    [Abstract] [Full Text] [Related]

  • 20. Survivin inhibitor YM155 suppresses gastric cancer xenograft growth in mice without affecting normal tissues.
    Cheng XJ, Lin JC, Ding YF, Zhu L, Ye J, Tu SP.
    Oncotarget; 2016 Feb 09; 7(6):7096-109. PubMed ID: 26771139
    [Abstract] [Full Text] [Related]

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