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182 related items for PubMed ID: 24867259
1. Nutlin-3 induces BCL2A1 expression by activating ELK1 through the mitochondrial p53-ROS-ERK1/2 pathway. Lee SY, Choi HC, Choe YJ, Shin SJ, Lee SH, Kim HS. Int J Oncol; 2014 Aug; 45(2):675-82. PubMed ID: 24867259 [Abstract] [Full Text] [Related]
2. ERK1/2 activation mediated by the nutlin‑3‑induced mitochondrial translocation of p53. Lee SY, Shin SJ, Kim HS. Int J Oncol; 2013 Mar; 42(3):1027-35. PubMed ID: 23314357 [Abstract] [Full Text] [Related]
3. Nutlin-3 induces HO-1 expression by activating JNK in a transcription-independent manner of p53. Choe YJ, Lee SY, Ko KW, Shin SJ, Kim HS. Int J Oncol; 2014 Mar; 44(3):761-8. PubMed ID: 24366007 [Abstract] [Full Text] [Related]
4. Molecular mechanisms of nutlin-induced apoptosis in multiple myeloma: evidence for p53-transcription-dependent and -independent pathways. Saha MN, Jiang H, Chang H. Cancer Biol Ther; 2010 Sep 15; 10(6):567-78. PubMed ID: 20595817 [Abstract] [Full Text] [Related]
8. The transcription-independent mitochondrial p53 program is a major contributor to nutlin-induced apoptosis in tumor cells. Vaseva AV, Marchenko ND, Moll UM. Cell Cycle; 2009 Jun 01; 8(11):1711-9. PubMed ID: 19411846 [Abstract] [Full Text] [Related]
9. Mouse double minute antagonist Nutlin-3a enhances chemotherapy-induced apoptosis in cancer cells with mutant p53 by activating E2F1. Ambrosini G, Sambol EB, Carvajal D, Vassilev LT, Singer S, Schwartz GK. Oncogene; 2007 May 24; 26(24):3473-81. PubMed ID: 17146434 [Abstract] [Full Text] [Related]
10. Involvement of ERK1/2-mediated ELK1/CHOP/DR5 pathway in 6-(methylsulfinyl)hexyl isothiocyanate-induced apoptosis of colorectal cancer cells. Yano S, Wu S, Sakao K, Hou DX. Biosci Biotechnol Biochem; 2019 May 24; 83(5):960-969. PubMed ID: 30730256 [Abstract] [Full Text] [Related]
11. DDTD, an isoflavone derivative, induces cell apoptosis through the reactive oxygen species/apoptosis signal-regulating kinase 1 pathway in human osteosarcoma cells. Chen JT, Fong YC, Li TM, Liu JF, Hsu CW, Chang CS, Tang CH. Eur J Pharmacol; 2008 Nov 12; 597(1-3):19-26. PubMed ID: 18822283 [Abstract] [Full Text] [Related]
12. Nutlin-3, a small-molecule MDM2 inhibitor, sensitizes Caki cells to TRAIL-induced apoptosis through p53-mediated PUMA upregulation and ROS-mediated DR5 upregulation. Park EJ, Choi KS, Yoo YH, Kwon TK. Anticancer Drugs; 2013 Mar 12; 24(3):260-9. PubMed ID: 23187459 [Abstract] [Full Text] [Related]
13. E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell lines. Kitagawa M, Aonuma M, Lee SH, Fukutake S, McCormick F. Oncogene; 2008 Sep 11; 27(40):5303-14. PubMed ID: 18521084 [Abstract] [Full Text] [Related]
14. p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2. Li PF, Dietz R, von Harsdorf R. EMBO J; 1999 Nov 01; 18(21):6027-36. PubMed ID: 10545114 [Abstract] [Full Text] [Related]
15. Small molecule inhibition of HDM2 leads to p53-mediated cell death in retinoblastoma cells. Elison JR, Cobrinik D, Claros N, Abramson DH, Lee TC. Arch Ophthalmol; 2006 Sep 01; 124(9):1269-75. PubMed ID: 16966622 [Abstract] [Full Text] [Related]
16. TRIAD1 Is a Novel Transcriptional Target of p53 and Regulates Nutlin-3a-Induced Cell Death. Lee J, An S, Choi YM, Jung JH, Li L, Meng H, Dong Y, Ahn KJ, An IS, Bae S. J Cell Biochem; 2017 Jul 01; 118(7):1733-1740. PubMed ID: 27935098 [Abstract] [Full Text] [Related]
17. Oridonin synergizes with Nutlin-3 in osteosarcoma cells by modulating the levels of multiple Bcl-2 family proteins. Wang XH, Zhang SF, Bao JT, Liu FY. Tumour Biol; 2017 Jun 01; 39(6):1010428317701638. PubMed ID: 28618955 [Abstract] [Full Text] [Related]
19. Elephantopus scaber induces apoptosis through ROS-dependent mitochondrial signaling pathway in HCT116 human colorectal carcinoma cells. Chan CK, Supriady H, Goh BH, Kadir HA. J Ethnopharmacol; 2015 Jun 20; 168():291-304. PubMed ID: 25861953 [Abstract] [Full Text] [Related]
20. Inhibition of p53-murine double minute 2 interaction by nutlin-3A stabilizes p53 and induces cell cycle arrest and apoptosis in Hodgkin lymphoma. Drakos E, Thomaides A, Medeiros LJ, Li J, Leventaki V, Konopleva M, Andreeff M, Rassidakis GZ. Clin Cancer Res; 2007 Jun 01; 13(11):3380-7. PubMed ID: 17545546 [Abstract] [Full Text] [Related] Page: [Next] [New Search]