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Journal Abstract Search


487 related items for PubMed ID: 24890366

  • 1. Gambogic acid suppresses hypoxia-induced hypoxia-inducible factor-1α/vascular endothelial growth factor expression via inhibiting phosphatidylinositol 3-kinase/Akt/mammalian target protein of rapamycin pathway in multiple myeloma cells.
    Wang F, Zhang W, Guo L, Bao W, Jin N, Liu R, Liu P, Wang Y, Guo Q, Chen B.
    Cancer Sci; 2014 Aug; 105(8):1063-70. PubMed ID: 24890366
    [Abstract] [Full Text] [Related]

  • 2. Chlorogenic acid inhibits hypoxia-induced angiogenesis via down-regulation of the HIF-1α/AKT pathway.
    Park JJ, Hwang SJ, Park JH, Lee HJ.
    Cell Oncol (Dordr); 2015 Apr; 38(2):111-8. PubMed ID: 25561311
    [Abstract] [Full Text] [Related]

  • 3. 4-Hydroxy estradiol but not 2-hydroxy estradiol induces expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor A through phosphatidylinositol 3-kinase/Akt/FRAP pathway in OVCAR-3 and A2780-CP70 human ovarian carcinoma cells.
    Gao N, Nester RA, Sarkar MA.
    Toxicol Appl Pharmacol; 2004 Apr 01; 196(1):124-35. PubMed ID: 15050414
    [Abstract] [Full Text] [Related]

  • 4. Magnolol suppresses hypoxia-induced angiogenesis via inhibition of HIF-1α/VEGF signaling pathway in human bladder cancer cells.
    Chen MC, Lee CF, Huang WH, Chou TC.
    Biochem Pharmacol; 2013 May 01; 85(9):1278-87. PubMed ID: 23416116
    [Abstract] [Full Text] [Related]

  • 5. Scorpiones, Scolopendra and Gekko Inhibit Lung Cancer Growth and Metastasis by Ameliorating Hypoxic Tumor Microenvironment via PI3K/AKT/mTOR/HIF-1α Signaling Pathway.
    Mao QY, Wang XQ, Lin F, Yu MW, Fan HT, Zheng Q, Liu LC, Zhang CC, Li DR, Lin HS.
    Chin J Integr Med; 2024 Sep 01; 30(9):799-808. PubMed ID: 38850481
    [Abstract] [Full Text] [Related]

  • 6. Gambogic acid inhibits angiogenesis through inhibiting PHD2-VHL-HIF-1α pathway.
    Lu N, Hui H, Yang H, Zhao K, Chen Y, You QD, Guo QL.
    Eur J Pharm Sci; 2013 May 13; 49(2):220-6. PubMed ID: 23501055
    [Abstract] [Full Text] [Related]

  • 7. Gambogic acid ameliorates diabetes-induced proliferative retinopathy through inhibition of the HIF-1α/VEGF expression via targeting PI3K/AKT pathway.
    Cui J, Gong R, Hu S, Cai L, Chen L.
    Life Sci; 2018 Jan 01; 192():293-303. PubMed ID: 29129773
    [Abstract] [Full Text] [Related]

  • 8. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C, Moore JW, Robertson N, Harris AL.
    Cancer Res; 2001 Oct 01; 61(19):7349-55. PubMed ID: 11585776
    [Abstract] [Full Text] [Related]

  • 9. The inhibition of hypoxia-induced angiogenesis and metastasis by cinnamaldehyde is mediated by decreasing HIF-1α protein synthesis via PI3K/Akt pathway.
    Patra K, Jana S, Sarkar A, Mandal DP, Bhattacharjee S.
    Biofactors; 2019 May 01; 45(3):401-415. PubMed ID: 30854715
    [Abstract] [Full Text] [Related]

  • 10. Knockdown of KLF5 suppresses hypoxia-induced resistance to cisplatin in NSCLC cells by regulating HIF-1α-dependent glycolysis through inactivation of the PI3K/Akt/mTOR pathway.
    Gong T, Cui L, Wang H, Wang H, Han N.
    J Transl Med; 2018 Jun 14; 16(1):164. PubMed ID: 29898734
    [Abstract] [Full Text] [Related]

  • 11. 12-Deoxyphorbol 13-palmitate inhibits the expression of VEGF and HIF-1α in MCF-7 cells by blocking the PI3K/Akt/mTOR signaling pathway.
    Yang Y, Cong H, Han C, Yue L, Dong H, Liu J.
    Oncol Rep; 2015 Oct 14; 34(4):1755-60. PubMed ID: 26239613
    [Abstract] [Full Text] [Related]

  • 12. Celecoxib Down-Regulates the Hypoxia-Induced Expression of HIF-1α and VEGF Through the PI3K/AKT Pathway in Retinal Pigment Epithelial Cells.
    Sun YZ, Cai N, Liu NN.
    Cell Physiol Biochem; 2017 Oct 14; 44(4):1640-1650. PubMed ID: 29216640
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis, and evaluation of antitumor activity in Pseudolaric acid B Azole derivatives: Novel and potent angiogenesis inhibitor via regulation of the PI3K/AKT and MAPK mediated HIF-1/VEGF signaling pathway.
    Deng H, Xu Q, Li XT, Huang X, Liu JY, Yan R, Quan ZS, Shen QK, Guo HY.
    Eur J Med Chem; 2024 Nov 15; 278():116813. PubMed ID: 39226705
    [Abstract] [Full Text] [Related]

  • 14. Akt1 activation can augment hypoxia-inducible factor-1alpha expression by increasing protein translation through a mammalian target of rapamycin-independent pathway.
    Pore N, Jiang Z, Shu HK, Bernhard E, Kao GD, Maity A.
    Mol Cancer Res; 2006 Jul 15; 4(7):471-9. PubMed ID: 16849522
    [Abstract] [Full Text] [Related]

  • 15. A group of novel HIF-1α inhibitors, glyceollins, blocks HIF-1α synthesis and decreases its stability via inhibition of the PI3K/AKT/mTOR pathway and Hsp90 binding.
    Lee SH, Jee JG, Bae JS, Liu KH, Lee YM.
    J Cell Physiol; 2015 Apr 15; 230(4):853-62. PubMed ID: 25204544
    [Abstract] [Full Text] [Related]

  • 16. Hypoxia-independent overexpression of hypoxia-inducible factor 1alpha as an early change in mouse hepatocarcinogenesis.
    Tanaka H, Yamamoto M, Hashimoto N, Miyakoshi M, Tamakawa S, Yoshie M, Tokusashi Y, Yokoyama K, Yaginuma Y, Ogawa K.
    Cancer Res; 2006 Dec 01; 66(23):11263-70. PubMed ID: 17145871
    [Abstract] [Full Text] [Related]

  • 17. Loss of Mel-18 induces tumor angiogenesis through enhancing the activity and expression of HIF-1α mediated by the PTEN/PI3K/Akt pathway.
    Park JH, Lee JY, Shin DH, Jang KS, Kim HJ, Kong G.
    Oncogene; 2011 Nov 10; 30(45):4578-89. PubMed ID: 21602890
    [Abstract] [Full Text] [Related]

  • 18. Activation of PI3K/mTOR signaling pathway contributes to induction of vascular endothelial growth factor by hCG in bovine developing luteal cells.
    Zhang Z, Yu D, Yin D, Wang Z.
    Anim Reprod Sci; 2011 May 10; 125(1-4):42-8. PubMed ID: 21477953
    [Abstract] [Full Text] [Related]

  • 19. Chrysin inhibits expression of hypoxia-inducible factor-1alpha through reducing hypoxia-inducible factor-1alpha stability and inhibiting its protein synthesis.
    Fu B, Xue J, Li Z, Shi X, Jiang BH, Fang J.
    Mol Cancer Ther; 2007 Jan 10; 6(1):220-6. PubMed ID: 17237281
    [Abstract] [Full Text] [Related]

  • 20. Delphinidin inhibits angiogenesis through the suppression of HIF-1α and VEGF expression in A549 lung cancer cells.
    Kim MH, Jeong YJ, Cho HJ, Hoe HS, Park KK, Park YY, Choi YH, Kim CH, Chang HW, Park YJ, Chung IK, Chang YC.
    Oncol Rep; 2017 Feb 10; 37(2):777-784. PubMed ID: 27959445
    [Abstract] [Full Text] [Related]


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