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537 related items for PubMed ID: 24890449

  • 1. Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Src‑mediated phosphorylation of EGF receptor tyrosine kinase.
    Kundu J, Choi BY, Jeong CH, Kundu JK, Chun KS.
    Oncol Rep; 2014 Aug; 32(2):821-8. PubMed ID: 24890449
    [Abstract] [Full Text] [Related]

  • 2. Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells.
    Park KW, Kundu J, Chae IG, Kim DH, Yu MH, Kundu JK, Chun KS.
    Int J Oncol; 2014 Apr; 44(4):1309-15. PubMed ID: 24481553
    [Abstract] [Full Text] [Related]

  • 3. Thymoquinone inhibits proliferation in gastric cancer via the STAT3 pathway in vivo and in vitro.
    Zhu WQ, Wang J, Guo XF, Liu Z, Dong WG.
    World J Gastroenterol; 2016 Apr 28; 22(16):4149-59. PubMed ID: 27122665
    [Abstract] [Full Text] [Related]

  • 4. Carnosic acid inhibits STAT3 signaling and induces apoptosis through generation of ROS in human colon cancer HCT116 cells.
    Kim DH, Park KW, Chae IG, Kundu J, Kim EH, Kundu JK, Chun KS.
    Mol Carcinog; 2016 Jun 28; 55(6):1096-110. PubMed ID: 26152521
    [Abstract] [Full Text] [Related]

  • 5. Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway.
    Li F, Rajendran P, Sethi G.
    Br J Pharmacol; 2010 Oct 28; 161(3):541-54. PubMed ID: 20880395
    [Abstract] [Full Text] [Related]

  • 6. Thymoquinone induces oxidative stress-mediated apoptosis through downregulation of Jak2/STAT3 signaling pathway in human melanoma cells.
    Raut PK, Lee HS, Joo SH, Chun KS.
    Food Chem Toxicol; 2021 Nov 28; 157():112604. PubMed ID: 34627931
    [Abstract] [Full Text] [Related]

  • 7. Isoliquiritigenin inhibits the proliferation of human renal carcinoma Caki cells through the ROS-mediated regulation of the Jak2/STAT3 pathway.
    Kim DH, Park JE, Chae IG, Park G, Lee S, Chun KS.
    Oncol Rep; 2017 Jul 28; 38(1):575-583. PubMed ID: 28560439
    [Abstract] [Full Text] [Related]

  • 8. Thymoquinone induces apoptosis of human epidermoid carcinoma A431 cells through ROS-mediated suppression of STAT3.
    Park JE, Kim DH, Ha E, Choi SM, Choi JS, Chun KS, Joo SH.
    Chem Biol Interact; 2019 Oct 01; 312():108799. PubMed ID: 31433961
    [Abstract] [Full Text] [Related]

  • 9. Thymoquinone induces apoptosis of human renal carcinoma Caki-1 cells by inhibiting JAK2/STAT3 through pro-oxidant effect.
    Chae IG, Song NY, Kim DH, Lee MY, Park JM, Chun KS.
    Food Chem Toxicol; 2020 May 01; 139():111253. PubMed ID: 32165235
    [Abstract] [Full Text] [Related]

  • 10. JAK2 regulation by licochalcone H inhibits the cell growth and induces apoptosis in oral squamous cell carcinoma.
    Oh HN, Oh KB, Lee MH, Seo JH, Kim E, Yoon G, Cho SS, Cho YS, Choi HW, Chae JI, Shim JH.
    Phytomedicine; 2019 Jan 01; 52():60-69. PubMed ID: 30599913
    [Abstract] [Full Text] [Related]

  • 11. Thymoquinone Augments Cisplatin-Induced Apoptosis on Esophageal Carcinoma Through Mitigating the Activation of JAK2/STAT3 Pathway.
    Hu X, Ma J, Vikash V, Li J, Wu D, Liu Y, Zhang J, Dong W.
    Dig Dis Sci; 2018 Jan 01; 63(1):126-134. PubMed ID: 29197940
    [Abstract] [Full Text] [Related]

  • 12. Molecular targeting of Akt by thymoquinone promotes G(1) arrest through translation inhibition of cyclin D1 and induces apoptosis in breast cancer cells.
    Rajput S, Kumar BN, Dey KK, Pal I, Parekh A, Mandal M.
    Life Sci; 2013 Nov 13; 93(21):783-90. PubMed ID: 24044882
    [Abstract] [Full Text] [Related]

  • 13. 15-Lipoxygenase-1-enhanced Src-Janus kinase 2-signal transducer and activator of transcription 3 stimulation and monocyte chemoattractant protein-1 expression require redox-sensitive activation of epidermal growth factor receptor in vascular wall remodeling.
    Singh NK, Wang D, Kundumani-Sridharan V, Van Quyen D, Niu J, Rao GN.
    J Biol Chem; 2011 Jun 24; 286(25):22478-88. PubMed ID: 21536676
    [Abstract] [Full Text] [Related]

  • 14. Generation of ROS by CAY10598 leads to inactivation of STAT3 signaling and induction of apoptosis in human colon cancer HCT116 cells.
    Chae IG, Kim DH, Kundu J, Jeong CH, Kundu JK, Chun KS.
    Free Radic Res; 2014 Nov 24; 48(11):1311-21. PubMed ID: 25096910
    [Abstract] [Full Text] [Related]

  • 15. Thymoquinone Induces Downregulation of BCR-ABL/JAK/STAT Pathway and Apoptosis in K562 Leukemia Cells.
    Al-Rawashde FA, Wan Taib WR, Ismail I, Johan MF, Al-Wajeeh AS, Al-Jamal HAN.
    Asian Pac J Cancer Prev; 2021 Dec 01; 22(12):3959-3965. PubMed ID: 34967577
    [Abstract] [Full Text] [Related]

  • 16. Concomitant inactivation of the epidermal growth factor receptor, phosphatidylinositol 3-kinase/Akt and Janus tyrosine kinase 2/signal transducer and activator of transcription 3 signalling pathways in cardiotoxin III-treated A549 cells.
    Su JC, Lin KL, Chien CM, Chuang PW, Chang LS, Lin SR.
    Clin Exp Pharmacol Physiol; 2010 Aug 01; 37(8):833-40. PubMed ID: 20456425
    [Abstract] [Full Text] [Related]

  • 17. Apigetrin inhibits gastric cancer progression through inducing apoptosis and regulating ROS-modulated STAT3/JAK2 pathway.
    Sun Q, Lu NN, Feng L.
    Biochem Biophys Res Commun; 2018 Mar 25; 498(1):164-170. PubMed ID: 29408335
    [Abstract] [Full Text] [Related]

  • 18. Ursolic Acid Induces Apoptosis in Colorectal Cancer Cells Partially via Upregulation of MicroRNA-4500 and Inhibition of JAK2/STAT3 Phosphorylation.
    Kim K, Shin EA, Jung JH, Park JE, Kim DS, Shim BS, Kim SH.
    Int J Mol Sci; 2018 Dec 29; 20(1):. PubMed ID: 30597956
    [Abstract] [Full Text] [Related]

  • 19. 4-Methoxydalbergione suppresses growth and induces apoptosis in human osteosarcoma cells in vitro and in vivo xenograft model through down-regulation of the JAK2/STAT3 pathway.
    Park KR, Yun HM, Quang TH, Oh H, Lee DS, Auh QS, Kim EC.
    Oncotarget; 2016 Feb 09; 7(6):6960-71. PubMed ID: 26755649
    [Abstract] [Full Text] [Related]

  • 20. A sesquiterpene lactone antrocin from Antrodia camphorata negatively modulates JAK2/STAT3 signaling via microRNA let-7c and induces apoptosis in lung cancer cells.
    Yeh CT, Huang WC, Rao YK, Ye M, Lee WH, Wang LS, Tzeng DT, Wu CH, Shieh YS, Huang CY, Chen YJ, Hsiao M, Wu AT, Yang Z, Tzeng YM.
    Carcinogenesis; 2013 Dec 09; 34(12):2918-28. PubMed ID: 23880305
    [Abstract] [Full Text] [Related]


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