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592 related items for PubMed ID: 24903225
1. Obatoclax analog SC-2001 inhibits STAT3 phosphorylation through enhancing SHP-1 expression and induces apoptosis in human breast cancer cells. Liu CY, Su JC, Ni MH, Tseng LM, Chu PY, Wang DS, Tai WT, Kao YP, Hung MH, Shiau CW, Chen KF. Breast Cancer Res Treat; 2014 Jul; 146(1):71-84. PubMed ID: 24903225 [Abstract] [Full Text] [Related]
2. RFX-1-dependent activation of SHP-1 inhibits STAT3 signaling in hepatocellular carcinoma cells. Su JC, Chiang HC, Tseng PH, Tai WT, Hsu CY, Li YS, Huang JW, Ko CH, Lin MW, Chu PY, Liu CY, Chen KF, Shiau CW. Carcinogenesis; 2014 Dec; 35(12):2807-14. PubMed ID: 25322871 [Abstract] [Full Text] [Related]
3. RFX1-dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells. Su JC, Tseng PH, Hsu CY, Tai WT, Huang JW, Ko CH, Lin MW, Liu CY, Chen KF, Shiau CW. Oncotarget; 2014 Jul 15; 5(13):4909-19. PubMed ID: 24952874 [Abstract] [Full Text] [Related]
4. A novel obatoclax derivative, SC-2001, induces apoptosis in hepatocellular carcinoma cells through SHP-1-dependent STAT3 inactivation. Chen KF, Su JC, Liu CY, Huang JW, Chen KC, Chen WL, Tai WT, Shiau CW. Cancer Lett; 2012 Aug 01; 321(1):27-35. PubMed ID: 22465052 [Abstract] [Full Text] [Related]
5. Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells. Liu CY, Tseng LM, Su JC, Chang KC, Chu PY, Tai WT, Shiau CW, Chen KF. Breast Cancer Res; 2013 Aug 01; 15(4):R63. PubMed ID: 23938089 [Abstract] [Full Text] [Related]
6. Sequential combination of docetaxel with a SHP-1 agonist enhanced suppression of p-STAT3 signaling and apoptosis in triple negative breast cancer cells. Liu CY, Chen KF, Chao TI, Chu PY, Huang CT, Huang TT, Yang HP, Wang WL, Lee CH, Lau KY, Tsai WC, Su JC, Wu CY, Chen MH, Shiau CW, Tseng LM. J Mol Med (Berl); 2017 Sep 01; 95(9):965-975. PubMed ID: 28578456 [Abstract] [Full Text] [Related]
7. SC-2001 overcomes STAT3-mediated sorafenib resistance through RFX-1/SHP-1 activation in hepatocellular carcinoma. Su JC, Tseng PH, Wu SH, Hsu CY, Tai WT, Li YS, Chen IT, Liu CY, Chen KF, Shiau CW. Neoplasia; 2014 Jul 01; 16(7):595-605. PubMed ID: 25047655 [Abstract] [Full Text] [Related]
8. Sorafenib analogue SC-60 induces apoptosis through the SHP-1/STAT3 pathway and enhances docetaxel cytotoxicity in triple-negative breast cancer cells. Liu CY, Su JC, Huang TT, Chu PY, Huang CT, Wang WL, Lee CH, Lau KY, Tsai WC, Yang HP, Shiau CW, Tseng LM, Chen KF. Mol Oncol; 2017 Mar 01; 11(3):266-279. PubMed ID: 28084011 [Abstract] [Full Text] [Related]
9. The tyrosine kinase inhibitor nintedanib activates SHP-1 and induces apoptosis in triple-negative breast cancer cells. Liu CY, Huang TT, Chu PY, Huang CT, Lee CH, Wang WL, Lau KY, Tsai WC, Chao TI, Su JC, Chen MH, Shiau CW, Tseng LM, Chen KF. Exp Mol Med; 2017 Aug 11; 49(8):e366. PubMed ID: 28798401 [Abstract] [Full Text] [Related]
10. Signal transducer and activator of transcription 3 as molecular therapy for non-small-cell lung cancer. Wang CY, Chao TT, Tai WT, Chang FY, Su WP, Chen YL, Chen PT, Weng CY, Yuan A, Shiau CW, Yu CJ, Chen KF. J Thorac Oncol; 2014 Apr 11; 9(4):488-96. PubMed ID: 24736071 [Abstract] [Full Text] [Related]
11. Small molecule 1'-acetoxychavicol acetate suppresses breast tumor metastasis by regulating the SHP-1/STAT3/MMPs signaling pathway. Wang J, Zhang L, Chen G, Zhang J, Li Z, Lu W, Liu M, Pang X. Breast Cancer Res Treat; 2014 Nov 11; 148(2):279-89. PubMed ID: 25301089 [Abstract] [Full Text] [Related]
12. Dovitinib induces apoptosis and overcomes sorafenib resistance in hepatocellular carcinoma through SHP-1-mediated inhibition of STAT3. Tai WT, Cheng AL, Shiau CW, Liu CY, Ko CH, Lin MW, Chen PJ, Chen KF. Mol Cancer Ther; 2012 Feb 11; 11(2):452-63. PubMed ID: 22180308 [Abstract] [Full Text] [Related]
13. Pharmacological Targeting SHP-1-STAT3 Signaling Is a Promising Therapeutic Approach for the Treatment of Colorectal Cancer. Fan LC, Teng HW, Shiau CW, Tai WT, Hung MH, Yang SH, Jiang JK, Chen KF. Neoplasia; 2015 Sep 11; 17(9):687-696. PubMed ID: 26476076 [Abstract] [Full Text] [Related]
14. WMJ-8-B, a novel hydroxamate derivative, induces MDA-MB-231 breast cancer cell death via the SHP-1-STAT3-survivin cascade. Chuang YF, Huang SW, Hsu YF, Yu MC, Ou G, Huang WJ, Hsu MJ. Br J Pharmacol; 2017 Sep 11; 174(17):2941-2961. PubMed ID: 28646512 [Abstract] [Full Text] [Related]
15. A sorafenib derivative and novel SHP-1 agonist, SC-59, acts synergistically with radiotherapy in hepatocellular carcinoma cells through inhibition of STAT3. Huang CY, Tai WT, Hsieh CY, Hsu WM, Lai YJ, Chen LJ, Shiau CW, Chen KF. Cancer Lett; 2014 Jul 28; 349(2):136-43. PubMed ID: 24735751 [Abstract] [Full Text] [Related]
16. β-Caryophyllene oxide inhibits constitutive and inducible STAT3 signaling pathway through induction of the SHP-1 protein tyrosine phosphatase. Kim C, Cho SK, Kapoor S, Kumar A, Vali S, Abbasi T, Kim SH, Sethi G, Ahn KS. Mol Carcinog; 2014 Oct 28; 53(10):793-806. PubMed ID: 23765383 [Abstract] [Full Text] [Related]
17. Evodiamine inhibits STAT3 signaling by inducing phosphatase shatterproof 1 in hepatocellular carcinoma cells. Yang J, Cai X, Lu W, Hu C, Xu X, Yu Q, Cao P. Cancer Lett; 2013 Jan 28; 328(2):243-51. PubMed ID: 23032719 [Abstract] [Full Text] [Related]
19. Signal transducer and activator of transcription 3 is a major kinase-independent target of sorafenib in hepatocellular carcinoma. Tai WT, Cheng AL, Shiau CW, Huang HP, Huang JW, Chen PJ, Chen KF. J Hepatol; 2011 Nov 28; 55(5):1041-8. PubMed ID: 21354226 [Abstract] [Full Text] [Related]
20. Capillarisin inhibits constitutive and inducible STAT3 activation through induction of SHP-1 and SHP-2 tyrosine phosphatases. Lee JH, Chiang SY, Nam D, Chung WS, Lee J, Na YS, Sethi G, Ahn KS. Cancer Lett; 2014 Apr 01; 345(1):140-8. PubMed ID: 24333736 [Abstract] [Full Text] [Related] Page: [Next] [New Search]