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980 related items for PubMed ID: 24914817

  • 1. A 2-amino quinoline, 5-(3-(2-(7-chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acid, interacts with PfMDR1 and inhibits its drug transport in Plasmodium falciparum.
    Edaye S, Reiling SJ, Leimanis ML, Wunderlich J, Rohrbach P, Georges E.
    Mol Biochem Parasitol; 2014 Jun; 195(1):34-42. PubMed ID: 24914817
    [Abstract] [Full Text] [Related]

  • 2. Mechanistic basis for multidrug resistance and collateral drug sensitivity conferred to the malaria parasite by polymorphisms in PfMDR1 and PfCRT.
    Shafik SH, Richards SN, Corry B, Martin RE.
    PLoS Biol; 2022 May; 20(5):e3001616. PubMed ID: 35507548
    [Abstract] [Full Text] [Related]

  • 3. A Redox-Active Fluorescent pH Indicator for Detecting Plasmodium falciparum Strains with Reduced Responsiveness to Quinoline Antimalarial Drugs.
    Jida M, Sanchez CP, Urgin K, Ehrhardt K, Mounien S, Geyer A, Elhabiri M, Lanzer M, Davioud-Charvet E.
    ACS Infect Dis; 2017 Feb 10; 3(2):119-131. PubMed ID: 28183182
    [Abstract] [Full Text] [Related]

  • 4. Genetic linkage analyses redefine the roles of PfCRT and PfMDR1 in drug accumulation and susceptibility in Plasmodium falciparum.
    Sanchez CP, Mayer S, Nurhasanah A, Stein WD, Lanzer M.
    Mol Microbiol; 2011 Nov 10; 82(4):865-78. PubMed ID: 21999470
    [Abstract] [Full Text] [Related]

  • 5. Verapamil-Sensitive Transport of Quinacrine and Methylene Blue via the Plasmodium falciparum Chloroquine Resistance Transporter Reduces the Parasite's Susceptibility to these Tricyclic Drugs.
    van Schalkwyk DA, Nash MN, Shafik SH, Summers RL, Lehane AM, Smith PJ, Martin RE.
    J Infect Dis; 2016 Mar 01; 213(5):800-10. PubMed ID: 26503982
    [Abstract] [Full Text] [Related]

  • 6. Chloroquine transport via the malaria parasite's chloroquine resistance transporter.
    Martin RE, Marchetti RV, Cowan AI, Howitt SM, Bröer S, Kirk K.
    Science; 2009 Sep 25; 325(5948):1680-2. PubMed ID: 19779197
    [Abstract] [Full Text] [Related]

  • 7. Prevalent pfmdr1 n86y mutant Plasmodium falciparum in Madagascar despite absence of pfcrt mutant strains.
    Rason MA, Andrianantenaina HB, Ariey F, Raveloson A, Domarle O, Randrianarivelojosia M.
    Am J Trop Med Hyg; 2007 Jun 25; 76(6):1079-83. PubMed ID: 17556614
    [Abstract] [Full Text] [Related]

  • 8. Monitoring of in vitro susceptibilities and molecular markers of resistance of Plasmodium falciparum isolates from Thai-Myanmar border to chloroquine, quinine, mefloquine and artesunate.
    Chaijaroenkul W, Wisedpanichkij R, Na-Bangchang K.
    Acta Trop; 2010 Feb 25; 113(2):190-4. PubMed ID: 19879850
    [Abstract] [Full Text] [Related]

  • 9. A Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug Piperaquine.
    Dhingra SK, Redhi D, Combrinck JM, Yeo T, Okombo J, Henrich PP, Cowell AN, Gupta P, Stegman ML, Hoke JM, Cooper RA, Winzeler E, Mok S, Egan TJ, Fidock DA.
    mBio; 2017 May 09; 8(3):. PubMed ID: 28487425
    [Abstract] [Full Text] [Related]

  • 10. Synergism between Pfcrt and Pfmdr1 genes could account for the slow recovery of chloroquine sensitive Plasmodium falciparum strains in Ghana after chloroquine withdrawal.
    Asare KK, Boampong JN, Duah NO, Afoakwah R, Sehgal R, Quashie NB.
    J Infect Public Health; 2017 May 09; 10(1):110-119. PubMed ID: 27026134
    [Abstract] [Full Text] [Related]

  • 11. Functional characteristics of the malaria parasite's "chloroquine resistance transporter": implications for chemotherapy.
    Summers RL, Martin RE.
    Virulence; 2010 May 09; 1(4):304-8. PubMed ID: 21178460
    [Abstract] [Full Text] [Related]

  • 12. Chloroquine resistance-conferring mutations in pfcrt give rise to a chloroquine-associated H+ leak from the malaria parasite's digestive vacuole.
    Lehane AM, Kirk K.
    Antimicrob Agents Chemother; 2008 Dec 09; 52(12):4374-80. PubMed ID: 18852275
    [Abstract] [Full Text] [Related]

  • 13. Efflux of a range of antimalarial drugs and 'chloroquine resistance reversers' from the digestive vacuole in malaria parasites with mutant PfCRT.
    Lehane AM, Kirk K.
    Mol Microbiol; 2010 Aug 09; 77(4):1039-51. PubMed ID: 20598081
    [Abstract] [Full Text] [Related]

  • 14. Rapid detection of Pfcrt and Pfmdr1 mutations in Plasmodium falciparum isolates by FRET and in vivo response to chloroquine among children from Osogbo, Nigeria.
    Ojurongbe O, Ogungbamigbe TO, Fagbenro-Beyioku AF, Fendel R, Kremsner PG, Kun JF.
    Malar J; 2007 Apr 11; 6():41. PubMed ID: 17428334
    [Abstract] [Full Text] [Related]

  • 15. Single nucleotide polymorphisms in Plasmodium falciparum V type H(+) pyrophosphatase gene (pfvp2) and their associations with pfcrt and pfmdr1 polymorphisms.
    Jovel IT, Ferreira PE, Veiga MI, Malmberg M, Mårtensson A, Kaneko A, Zakeri S, Murillo C, Nosten F, Björkman A, Ursing J.
    Infect Genet Evol; 2014 Jun 11; 24():111-5. PubMed ID: 24657918
    [Abstract] [Full Text] [Related]

  • 16. Pfcrt mutant haplotypes may not correspond with chloroquine resistance.
    Goswami D, Dhiman S, Rabha B, Kumar D, Baruah I, Sharma DK, Veer V.
    J Infect Dev Ctries; 2014 Jun 11; 8(6):768-73. PubMed ID: 24916876
    [Abstract] [Full Text] [Related]

  • 17. [The point mutations in Pfcrt and Pfmdr1 genes in Plasmodium falciparum isolated from Hainan Province].
    Guan YY, Tang LH, Hu L, Feng XP, Liu DQ.
    Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi; 2005 Jun 30; 23(3):135-9. PubMed ID: 16299999
    [Abstract] [Full Text] [Related]

  • 18. Molecular Mechanisms for Drug Hypersensitivity Induced by the Malaria Parasite's Chloroquine Resistance Transporter.
    Richards SN, Nash MN, Baker ES, Webster MW, Lehane AM, Shafik SH, Martin RE.
    PLoS Pathog; 2016 Jul 30; 12(7):e1005725. PubMed ID: 27441371
    [Abstract] [Full Text] [Related]

  • 19. Quinoline-resistance reversing agents for the malaria parasite Plasmodium falciparum.
    van Schalkwyk DA, Egan TJ.
    Drug Resist Updat; 2006 Jul 30; 9(4-5):211-26. PubMed ID: 17064951
    [Abstract] [Full Text] [Related]

  • 20. Increased prevalence of the Plasmodium falciparum Pfmdr1 86N genotype among field isolates from Franceville, Gabon after replacement of chloroquine by artemether-lumefantrine and artesunate-mefloquine.
    Lekana-Douki JB, Dinzouna Boutamba SD, Zatra R, Zang Edou SE, Ekomy H, Bisvigou U, Toure-Ndouo FS.
    Infect Genet Evol; 2011 Mar 30; 11(2):512-7. PubMed ID: 21251998
    [Abstract] [Full Text] [Related]

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