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237 related items for PubMed ID: 24927176

  • 1. TRAIL enhances apoptosis of human hepatocellular carcinoma cells sensitized by hepatitis C virus infection: therapeutic implications.
    Jang JY, Kim SJ, Cho EK, Jeong SW, Park EJ, Lee WC, Lee SH, Kim SG, Kim YS, Kim HS, Kim BS, Lin W, Chung RT.
    PLoS One; 2014; 9(6):e98171. PubMed ID: 24927176
    [Abstract] [Full Text] [Related]

  • 2. Hepatitis C virus sensitizes host cells to TRAIL-induced apoptosis by up-regulating DR4 and DR5 via a MEK1-dependent pathway.
    Deng Z, Yan H, Hu J, Zhang S, Peng P, Liu Q, Guo D.
    PLoS One; 2012; 7(5):e37700. PubMed ID: 22662193
    [Abstract] [Full Text] [Related]

  • 3. HIV infection increases HCV-induced hepatocyte apoptosis.
    Jang JY, Shao RX, Lin W, Weinberg E, Chung WJ, Tsai WL, Zhao H, Goto K, Zhang L, Mendez-Navarro J, Jilg N, Peng LF, Brockman MA, Chung RT.
    J Hepatol; 2011 Apr; 54(4):612-20. PubMed ID: 21146890
    [Abstract] [Full Text] [Related]

  • 4. Hepatitis C virus core protein modulates TRAIL-mediated apoptosis by enhancing Bid cleavage and activation of mitochondria apoptosis signaling pathway.
    Chou AH, Tsai HF, Wu YY, Hu CY, Hwang LH, Hsu PI, Hsu PN.
    J Immunol; 2005 Feb 15; 174(4):2160-6. PubMed ID: 15699147
    [Abstract] [Full Text] [Related]

  • 5. Salirasib sensitizes hepatocarcinoma cells to TRAIL-induced apoptosis through DR5 and survivin-dependent mechanisms.
    Charette N, De Saeger C, Horsmans Y, Leclercq I, Stärkel P.
    Cell Death Dis; 2013 Jan 24; 4(1):e471. PubMed ID: 23348585
    [Abstract] [Full Text] [Related]

  • 6. TRAIL induces apoptosis but not necroptosis in colorectal and pancreatic cancer cells preferentially via the TRAIL-R2/DR5 receptor.
    Nahacka Z, Svadlenka J, Peterka M, Ksandrova M, Benesova S, Neuzil J, Andera L.
    Biochim Biophys Acta Mol Cell Res; 2018 Mar 24; 1865(3):522-531. PubMed ID: 29278689
    [Abstract] [Full Text] [Related]

  • 7. Expression of TRAIL and the death receptors DR4 and DR5 correlates with progression of degeneration in human intervertebral disks.
    Bertram H, Nerlich A, Omlor G, Geiger F, Zimmermann G, Fellenberg J.
    Mod Pathol; 2009 Jul 24; 22(7):895-905. PubMed ID: 19305384
    [Abstract] [Full Text] [Related]

  • 8. 5, 7-Dimethoxyflavone sensitizes TRAIL-induced apoptosis through DR5 upregulation in hepatocellular carcinoma cells.
    Yang JF, Cao JG, Tian L, Liu F.
    Cancer Chemother Pharmacol; 2012 Jan 24; 69(1):195-206. PubMed ID: 21660448
    [Abstract] [Full Text] [Related]

  • 9. Notch1 signaling sensitizes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human hepatocellular carcinoma cells by inhibiting Akt/Hdm2-mediated p53 degradation and up-regulating p53-dependent DR5 expression.
    Wang C, Qi R, Li N, Wang Z, An H, Zhang Q, Yu Y, Cao X.
    J Biol Chem; 2009 Jun 12; 284(24):16183-16190. PubMed ID: 19376776
    [Abstract] [Full Text] [Related]

  • 10. 6-Methoxydihydrosanguinarine exhibits cytotoxicity and sensitizes TRAIL-induced apoptosis of hepatocellular carcinoma cells through ROS-mediated upregulation of DR5.
    Wang LL, Li RT, Zang ZH, Song YX, Zhang YZ, Zhang TF, Wang FZ, Hao GP, Cao L.
    Med Oncol; 2023 Aug 11; 40(9):266. PubMed ID: 37566135
    [Abstract] [Full Text] [Related]

  • 11. Cisplatin-mediated c-myc overexpression and cytochrome c (cyt c) release result in the up-regulation of the death receptors DR4 and DR5 and the activation of caspase 3 and caspase 9, likely responsible for the TRAIL-sensitizing effect of cisplatin.
    Zhu X, Zhang K, Wang Q, Chen S, Gou Y, Cui Y, Li Q.
    Med Oncol; 2015 Apr 11; 32(4):133. PubMed ID: 25796504
    [Abstract] [Full Text] [Related]

  • 12. Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation.
    Kim JY, Kim EH, Park SS, Lim JH, Kwon TK, Choi KS.
    J Cell Biochem; 2008 Dec 15; 105(6):1386-98. PubMed ID: 18980244
    [Abstract] [Full Text] [Related]

  • 13. Hepatocyte expression of TRAIL pathway regulators correlates with histopathological and clinical parameters in chronic HCV infection.
    Brost S, Zimmermann A, Koschny R, Sykora J, Stremmel W, Schirmacher P, Walczak H, Ganten TM.
    Pathol Res Pract; 2014 Feb 15; 210(2):83-91. PubMed ID: 24268735
    [Abstract] [Full Text] [Related]

  • 14. CAPE promotes TRAIL-induced apoptosis through the upregulation of TRAIL receptors via activation of p38 and suppression of JNK in SK-Hep1 hepatocellular carcinoma cells.
    Kim EY, Ryu JH, Kim AK.
    Int J Oncol; 2013 Oct 15; 43(4):1291-300. PubMed ID: 23857473
    [Abstract] [Full Text] [Related]

  • 15. TRAIL signaling is mediated by DR4 in pancreatic tumor cells despite the expression of functional DR5.
    Lemke J, Noack A, Adam D, Tchikov V, Bertsch U, Röder C, Schütze S, Wajant H, Kalthoff H, Trauzold A.
    J Mol Med (Berl); 2010 Jul 15; 88(7):729-40. PubMed ID: 20354842
    [Abstract] [Full Text] [Related]

  • 16. An HPLC method associated with a thermodynamic analysis to compare the binding of TRAIL and its nanovectorized form to death receptors DR4 and DR5 and their relationship to cytotoxicity.
    Guillaume YC, Lethier L, André C.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2016 Nov 15; 1036-1037():142-148. PubMed ID: 27750195
    [Abstract] [Full Text] [Related]

  • 17. Reactivation of death receptor 4 (DR4) expression sensitizes medulloblastoma cell lines to TRAIL.
    Aguilera DG, Das CM, Sinnappah-Kang ND, Joyce C, Taylor PH, Wen S, Hasselblatt M, Paulus W, Fuller G, Wolff JE, Gopalakrishnan V.
    J Neurooncol; 2009 Jul 15; 93(3):303-18. PubMed ID: 19148581
    [Abstract] [Full Text] [Related]

  • 18. Camptothecin sensitizes human hepatoma Hep3B cells to TRAIL-mediated apoptosis via ROS-dependent death receptor 5 upregulation with the involvement of MAPKs.
    Jayasooriya RG, Choi YH, Hyun JW, Kim GY.
    Environ Toxicol Pharmacol; 2014 Nov 15; 38(3):959-67. PubMed ID: 25461556
    [Abstract] [Full Text] [Related]

  • 19. Death receptor 5 is activated by fucosylation in colon cancer cells.
    Zhang B, van Roosmalen IAM, Reis CR, Setroikromo R, Quax WJ.
    FEBS J; 2019 Feb 15; 286(3):555-571. PubMed ID: 30589515
    [Abstract] [Full Text] [Related]

  • 20. Modulation of TRAIL resistance in colon carcinoma cells: different contributions of DR4 and DR5.
    van Geelen CM, Pennarun B, Le PT, de Vries EG, de Jong S.
    BMC Cancer; 2011 Jan 27; 11():39. PubMed ID: 21272366
    [Abstract] [Full Text] [Related]

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