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235 related items for PubMed ID: 24931193

  • 1. Constitutive activities in the thyrotropin receptor: regulation and significance.
    Kleinau G, Biebermann H.
    Adv Pharmacol; 2014; 70():81-119. PubMed ID: 24931193
    [Abstract] [Full Text] [Related]

  • 2. Thyroid-stimulating hormone and thyroid-stimulating hormone receptor structure-function relationships.
    Szkudlinski MW, Fremont V, Ronin C, Weintraub BD.
    Physiol Rev; 2002 Apr; 82(2):473-502. PubMed ID: 11917095
    [Abstract] [Full Text] [Related]

  • 3. Mutations in the mouse TSH receptor equivalent to human constitutively activating TSH receptor mutations also cause constitutive activity.
    Neumann S, Krohn K, Chey S, Paschke R.
    Horm Metab Res; 2001 May; 33(5):263-9. PubMed ID: 11440271
    [Abstract] [Full Text] [Related]

  • 4. New pathogenic thyrotropin receptor mutations decipher differentiated activity switching at a conserved helix 6 motif of family A GPCR.
    Biebermann H, Winkler F, Handke D, Teichmann A, Gerling B, Cameron F, Eichhorst J, Grüters A, Wiesner B, Kühnen P, Krude H, Kleinau G.
    J Clin Endocrinol Metab; 2012 Feb; 97(2):E228-32. PubMed ID: 22112806
    [Abstract] [Full Text] [Related]

  • 5. Identification and evaluation of constitutively active thyroid stimulating hormone receptor mutations.
    Lado-Abeal J, Quisenberry LR, Castro-Piedras I.
    Methods Enzymol; 2010 Feb; 484():375-95. PubMed ID: 21036242
    [Abstract] [Full Text] [Related]

  • 6. Controversial constitutive TSHR activity: patients, physiology, and in vitro characterization.
    Huth S, Jaeschke H, Schaarschmidt J, Paschke R.
    Horm Metab Res; 2014 Jun; 46(7):453-61. PubMed ID: 24845969
    [Abstract] [Full Text] [Related]

  • 7. Thyrotropin receptor mutations as a tool to understand thyrotropin receptor action.
    Wonerow P, Neumann S, Gudermann T, Paschke R.
    J Mol Med (Berl); 2001 Dec; 79(12):707-21. PubMed ID: 11862314
    [Abstract] [Full Text] [Related]

  • 8. Shared sporadic and somatic thyrotropin receptor mutations display more active in vitro activities than familial thyrotropin receptor mutations.
    Lueblinghoff J, Eszlinger M, Jaeschke H, Mueller S, Bircan R, Gozu H, Sancak S, Akalin S, Paschke R.
    Thyroid; 2011 Mar; 21(3):221-9. PubMed ID: 21190443
    [Abstract] [Full Text] [Related]

  • 9. TSH receptor monoclonal antibodies with agonist, antagonist, and inverse agonist activities.
    Sanders J, Miguel RN, Furmaniak J, Smith BR.
    Methods Enzymol; 2010 Mar; 485():393-420. PubMed ID: 21050929
    [Abstract] [Full Text] [Related]

  • 10. Comparative proteomic analysis to dissect differences in signal transduction in activating TSH receptor mutations in the thyroid.
    Krause K, Boisnard A, Ihling C, Ludgate M, Eszlinger M, Krohn K, Sinz A, Fuhrer D.
    Int J Biochem Cell Biol; 2012 Feb; 44(2):290-301. PubMed ID: 22074661
    [Abstract] [Full Text] [Related]

  • 11. Identification and functional characterization of two novel activating thyrotropin receptor mutants in toxic thyroid follicular adenomas.
    Castro I, Lima L, Seoane R, Lado-Abeal J.
    Thyroid; 2009 Jun; 19(6):645-9. PubMed ID: 19499991
    [Abstract] [Full Text] [Related]

  • 12. Proper targeting and activity of a nonfunctioning thyroid-stimulating hormone receptor (TSHr) combining an inactivating and activating TSHr mutation in one receptor.
    Agretti P, De Marco G, Collecchi P, Chiovato L, Vitti P, Pinchera A, Tonacchera M.
    Eur J Biochem; 2003 Sep; 270(18):3839-47. PubMed ID: 12950268
    [Abstract] [Full Text] [Related]

  • 13. A familial thyrotropin (TSH) receptor mutation provides in vivo evidence that the inositol phosphates/Ca2+ cascade mediates TSH action on thyroid hormone synthesis.
    Grasberger H, Van Sande J, Hag-Dahood Mahameed A, Tenenbaum-Rakover Y, Refetoff S.
    J Clin Endocrinol Metab; 2007 Jul; 92(7):2816-20. PubMed ID: 17456567
    [Abstract] [Full Text] [Related]

  • 14. A new phenotype of nongoitrous and nonautoimmune hyperthyroidism caused by a heterozygous thyrotropin receptor mutation in transmembrane helix 6.
    Winkler F, Kleinau G, Tarnow P, Rediger A, Grohmann L, Gaetjens I, Krause G, L'Allemand D, Grüters A, Krude H, Biebermann H.
    J Clin Endocrinol Metab; 2010 Aug; 95(8):3605-10. PubMed ID: 20501679
    [Abstract] [Full Text] [Related]

  • 15. Current standards, variations, and pitfalls for the determination of constitutive TSHR activity in vitro.
    Mueller S, Jaeschke H, Paschke R.
    Methods Enzymol; 2010 Aug; 485():421-36. PubMed ID: 21050930
    [Abstract] [Full Text] [Related]

  • 16. Oncogenic potential of a mutant human thyrotropin receptor expressed in FRTL-5 cells.
    Fournes B, Monier R, Michiels F, Milgrom E, Misrahi M, Feunteun J.
    Oncogene; 1998 Feb 26; 16(8):985-90. PubMed ID: 9519872
    [Abstract] [Full Text] [Related]

  • 17. Lack of in vitro constitutive activity for four previously reported TSH receptor mutations identified in patients with nonautoimmune hyperthyroidism and hot thyroid carcinomas.
    Jaeschke H, Mueller S, Eszlinger M, Paschke R.
    Clin Endocrinol (Oxf); 2010 Dec 26; 73(6):815-20. PubMed ID: 20846293
    [Abstract] [Full Text] [Related]

  • 18. Intracellular entrapment of wild-type TSH receptor by oligomerization with mutants linked to dominant TSH resistance.
    Calebiro D, de Filippis T, Lucchi S, Covino C, Panigone S, Beck-Peccoz P, Dunlap D, Persani L.
    Hum Mol Genet; 2005 Oct 15; 14(20):2991-3002. PubMed ID: 16135555
    [Abstract] [Full Text] [Related]

  • 19. Somatic mutations in the thyrotropin receptor gene and not in the Gs alpha protein gene in 31 toxic thyroid nodules.
    Führer D, Holzapfel HP, Wonerow P, Scherbaum WA, Paschke R.
    J Clin Endocrinol Metab; 1997 Nov 15; 82(11):3885-91. PubMed ID: 9360556
    [Abstract] [Full Text] [Related]

  • 20. The extracellular domain suppresses constitutive activity of the transmembrane domain of the human TSH receptor: implications for hormone-receptor interaction and antagonist design.
    Zhang M, Tong KP, Fremont V, Chen J, Narayan P, Puett D, Weintraub BD, Szkudlinski MW.
    Endocrinology; 2000 Sep 15; 141(9):3514-7. PubMed ID: 10965926
    [Abstract] [Full Text] [Related]

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