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Journal Abstract Search

143 related items for PubMed ID: 24935013

  • 1. Targeted therapies: ibrutinib resonates with us.
    Villanueva MT.
    Nat Rev Clin Oncol; 2014 Jul; 11(7):380. PubMed ID: 24935013
    [No Abstract] [Full Text] [Related]

  • 2. PLCG2 C2 domain mutations co-occur with BTK and PLCG2 resistance mutations in chronic lymphocytic leukemia undergoing ibrutinib treatment.
    Jones D, Woyach JA, Zhao W, Caruthers S, Tu H, Coleman J, Byrd JC, Johnson AJ, Lozanski G.
    Leukemia; 2017 Jul; 31(7):1645-1647. PubMed ID: 28366935
    [No Abstract] [Full Text] [Related]

  • 3. Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib.
    Woyach JA, Furman RR, Liu TM, Ozer HG, Zapatka M, Ruppert AS, Xue L, Li DH, Steggerda SM, Versele M, Dave SS, Zhang J, Yilmaz AS, Jaglowski SM, Blum KA, Lozanski A, Lozanski G, James DF, Barrientos JC, Lichter P, Stilgenbauer S, Buggy JJ, Chang BY, Johnson AJ, Byrd JC.
    N Engl J Med; 2014 Jun 12; 370(24):2286-94. PubMed ID: 24869598
    [Abstract] [Full Text] [Related]

  • 4. Deciphering Ibrutinib Resistance in Chronic Lymphocytic Leukemia.
    Lenz G.
    J Clin Oncol; 2017 May 01; 35(13):1451-1452. PubMed ID: 28291389
    [No Abstract] [Full Text] [Related]

  • 5. Ibrutinib resistance in chronic lymphocytic leukemia.
    Furman RR, Cheng S, Lu P, Setty M, Perez AR, Guo A, Racchumi J, Xu G, Wu H, Ma J, Steggerda SM, Coleman M, Leslie C, Wang YL.
    N Engl J Med; 2014 Jun 12; 370(24):2352-4. PubMed ID: 24869597
    [No Abstract] [Full Text] [Related]

  • 6. Ibrutinib-naïve chronic lymphocytic leukemia lacks Bruton tyrosine kinase mutations associated with treatment resistance.
    Famà R, Bomben R, Rasi S, Dal Bo M, Ciardullo C, Monti S, Rossi F, D'Agaro T, Zucchetto A, Gattei V, Gaidano G, Rossi D.
    Blood; 2014 Dec 11; 124(25):3831-3. PubMed ID: 25498455
    [No Abstract] [Full Text] [Related]

  • 7. Hypermorphic mutation of phospholipase C, γ2 acquired in ibrutinib-resistant CLL confers BTK independency upon B-cell receptor activation.
    Liu TM, Woyach JA, Zhong Y, Lozanski A, Lozanski G, Dong S, Strattan E, Lehman A, Zhang X, Jones JA, Flynn J, Andritsos LA, Maddocks K, Jaglowski SM, Blum KA, Byrd JC, Dubovsky JA, Johnson AJ.
    Blood; 2015 Jul 02; 126(1):61-8. PubMed ID: 25972157
    [Abstract] [Full Text] [Related]

  • 8. BTKC481S-Mediated Resistance to Ibrutinib in Chronic Lymphocytic Leukemia.
    Woyach JA, Ruppert AS, Guinn D, Lehman A, Blachly JS, Lozanski A, Heerema NA, Zhao W, Coleman J, Jones D, Abruzzo L, Gordon A, Mantel R, Smith LL, McWhorter S, Davis M, Doong TJ, Ny F, Lucas M, Chase W, Jones JA, Flynn JM, Maddocks K, Rogers K, Jaglowski S, Andritsos LA, Awan FT, Blum KA, Grever MR, Lozanski G, Johnson AJ, Byrd JC.
    J Clin Oncol; 2017 May 01; 35(13):1437-1443. PubMed ID: 28418267
    [Abstract] [Full Text] [Related]

  • 9. Ibrutinib treatment of CLL: the cancer fights back.
    Young RM, Staudt LM.
    Cancer Cell; 2014 Jul 14; 26(1):11-3. PubMed ID: 25026208
    [Abstract] [Full Text] [Related]

  • 10. Using high-sensitivity sequencing for the detection of mutations in BTK and PLCγ2 genes in cellular and cell-free DNA and correlation with progression in patients treated with BTK inhibitors.
    Albitar A, Ma W, DeDios I, Estella J, Ahn I, Farooqui M, Wiestner A, Albitar M.
    Oncotarget; 2017 Mar 14; 8(11):17936-17944. PubMed ID: 28212557
    [Abstract] [Full Text] [Related]

  • 11. Are BTK and PLCG2 mutations necessary and sufficient for ibrutinib resistance in chronic lymphocytic leukemia?
    Lampson BL, Brown JR.
    Expert Rev Hematol; 2018 Mar 14; 11(3):185-194. PubMed ID: 29381098
    [Abstract] [Full Text] [Related]

  • 12. The evolutionary landscape of chronic lymphocytic leukemia treated with ibrutinib targeted therapy.
    Landau DA, Sun C, Rosebrock D, Herman SEM, Fein J, Sivina M, Underbayev C, Liu D, Hoellenriegel J, Ravichandran S, Farooqui MZH, Zhang W, Cibulskis C, Zviran A, Neuberg DS, Livitz D, Bozic I, Leshchiner I, Getz G, Burger JA, Wiestner A, Wu CJ.
    Nat Commun; 2017 Dec 19; 8(1):2185. PubMed ID: 29259203
    [Abstract] [Full Text] [Related]

  • 13. Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition.
    Burger JA, Landau DA, Taylor-Weiner A, Bozic I, Zhang H, Sarosiek K, Wang L, Stewart C, Fan J, Hoellenriegel J, Sivina M, Dubuc AM, Fraser C, Han Y, Li S, Livak KJ, Zou L, Wan Y, Konoplev S, Sougnez C, Brown JR, Abruzzo LV, Carter SL, Keating MJ, Davids MS, Wierda WG, Cibulskis K, Zenz T, Werner L, Dal Cin P, Kharchencko P, Neuberg D, Kantarjian H, Lander E, Gabriel S, O'Brien S, Letai A, Weitz DA, Nowak MA, Getz G, Wu CJ.
    Nat Commun; 2016 May 20; 7():11589. PubMed ID: 27199251
    [Abstract] [Full Text] [Related]

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  • 16. Identification of a structurally novel BTK mutation that drives ibrutinib resistance in CLL.
    Sharma S, Galanina N, Guo A, Lee J, Kadri S, Van Slambrouck C, Long B, Wang W, Ming M, Furtado LV, Segal JP, Stock W, Venkataraman G, Tang WJ, Lu P, Wang YL.
    Oncotarget; 2016 Oct 18; 7(42):68833-68841. PubMed ID: 27626698
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  • 20. The Phospholipase Cγ2 Mutants R665W and L845F Identified in Ibrutinib-resistant Chronic Lymphocytic Leukemia Patients Are Hypersensitive to the Rho GTPase Rac2 Protein.
    Walliser C, Hermkes E, Schade A, Wiese S, Deinzer J, Zapatka M, Désiré L, Mertens D, Stilgenbauer S, Gierschik P.
    J Biol Chem; 2016 Oct 14; 291(42):22136-22148. PubMed ID: 27542411
    [Abstract] [Full Text] [Related]

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