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222 related items for PubMed ID: 24939733

  • 1. Glycerol-3-phosphate acyltransferase-4-deficient mice are protected from diet-induced insulin resistance by the enhanced association of mTOR and rictor.
    Zhang C, Cooper DE, Grevengoed TJ, Li LO, Klett EL, Eaton JM, Harris TE, Coleman RA.
    Am J Physiol Endocrinol Metab; 2014 Aug 01; 307(3):E305-15. PubMed ID: 24939733
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  • 2. Inhibited insulin signaling in mouse hepatocytes is associated with increased phosphatidic acid but not diacylglycerol.
    Zhang C, Hwarng G, Cooper DE, Grevengoed TJ, Eaton JM, Natarajan V, Harris TE, Coleman RA.
    J Biol Chem; 2015 Feb 06; 290(6):3519-28. PubMed ID: 25512376
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  • 3. Glycerolipid signals alter mTOR complex 2 (mTORC2) to diminish insulin signaling.
    Zhang C, Wendel AA, Keogh MR, Harris TE, Chen J, Coleman RA.
    Proc Natl Acad Sci U S A; 2012 Jan 31; 109(5):1667-72. PubMed ID: 22307628
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  • 8. GPAT1 Activity and Abundant Palmitic Acid Impair Insulin Suppression of Hepatic Glucose Production in Primary Mouse Hepatocytes.
    Zhang C, Steadman M, Santos HP, Shaikh SR, Xavier RM.
    J Nutr; 2024 Apr 31; 154(4):1109-1118. PubMed ID: 38354952
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  • 9. Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.
    Tang Y, Wallace M, Sanchez-Gurmaches J, Hsiao WY, Li H, Lee PL, Vernia S, Metallo CM, Guertin DA.
    Nat Commun; 2016 Apr 21; 7():11365. PubMed ID: 27098609
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  • 13. Identification of a novel sn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient in Agpat6-/- mice.
    Nagle CA, Vergnes L, Dejong H, Wang S, Lewin TM, Reue K, Coleman RA.
    J Lipid Res; 2008 Apr 21; 49(4):823-31. PubMed ID: 18192653
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  • 14. Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin.
    Toschi A, Lee E, Xu L, Garcia A, Gadir N, Foster DA.
    Mol Cell Biol; 2009 Mar 21; 29(6):1411-20. PubMed ID: 19114562
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  • 15. Thioesterase superfamily member 2 promotes hepatic insulin resistance in the setting of glycerol-3-phosphate acyltransferase 1-induced steatosis.
    Tillander V, Miniami A, Alves-Bezerra M, Coleman RA, Cohen DE.
    J Biol Chem; 2019 Feb 08; 294(6):2009-2020. PubMed ID: 30523156
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  • 17. Hepatic mTORC2 Signaling Facilitates Acute Glucagon Receptor Enhancement of Insulin-Stimulated Glucose Homeostasis in Mice.
    Kim T, Nason S, Antipenko J, Finan B, Shalev A, DiMarchi R, Habegger KM.
    Diabetes; 2022 Oct 01; 71(10):2123-2135. PubMed ID: 35877180
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  • 18. Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity.
    Lamming DW, Ye L, Katajisto P, Goncalves MD, Saitoh M, Stevens DM, Davis JG, Salmon AB, Richardson A, Ahima RS, Guertin DA, Sabatini DM, Baur JA.
    Science; 2012 Mar 30; 335(6076):1638-43. PubMed ID: 22461615
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