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1847 related items for PubMed ID: 24952138

  • 1. Phenethyl isothiocyanate induces DNA damage-associated G2/M arrest and subsequent apoptosis in oral cancer cells with varying p53 mutations.
    Yeh YT, Yeh H, Su SH, Lin JS, Lee KJ, Shyu HW, Chen ZF, Huang SY, Su SJ.
    Free Radic Biol Med; 2014 Sep; 74():1-13. PubMed ID: 24952138
    [Abstract] [Full Text] [Related]

  • 2. Benzyl isothiocyanate promotes apoptosis of oral cancer cells via an acute redox stress-mediated DNA damage response.
    Yeh YT, Hsu YN, Huang SY, Lin JS, Chen ZF, Chow NH, Su SH, Shyu HW, Lin CC, Huang WT, Yeh H, Chih YC, Huang YH, Su SJ.
    Food Chem Toxicol; 2016 Nov; 97():336-345. PubMed ID: 27693243
    [Abstract] [Full Text] [Related]

  • 3. Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteogenic sarcoma U-2 OS cells.
    Wu CL, Huang AC, Yang JS, Liao CL, Lu HF, Chou ST, Ma CY, Hsia TC, Ko YC, Chung JG.
    J Orthop Res; 2011 Aug; 29(8):1199-209. PubMed ID: 21374707
    [Abstract] [Full Text] [Related]

  • 4. Phenethyl isothiocyanate triggers apoptosis in human malignant melanoma A375.S2 cells through reactive oxygen species and the mitochondria-dependent pathways.
    Huang SH, Hsu MH, Hsu SC, Yang JS, Huang WW, Huang AC, Hsiao YP, Yu CC, Chung JG.
    Hum Exp Toxicol; 2014 Mar; 33(3):270-83. PubMed ID: 23760257
    [Abstract] [Full Text] [Related]

  • 5. Phenethyl isothiocyanate (PEITC) promotes G2/M phase arrest via p53 expression and induces apoptosis through caspase- and mitochondria-dependent signaling pathways in human prostate cancer DU 145 cells.
    Tang NY, Huang YT, Yu CS, Ko YC, Wu SH, Ji BC, Yang JS, Yang JL, Hsia TC, Chen YY, Chung JG.
    Anticancer Res; 2011 May; 31(5):1691-702. PubMed ID: 21617228
    [Abstract] [Full Text] [Related]

  • 6. Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
    Wu SJ, Ng LT, Lin CC.
    Eur J Pharmacol; 2005 Aug 22; 518(2-3):96-106. PubMed ID: 16054126
    [Abstract] [Full Text] [Related]

  • 7. Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.
    Huang SH, Wu LW, Huang AC, Yu CC, Lien JC, Huang YP, Yang JS, Yang JH, Hsiao YP, Wood WG, Yu CS, Chung JG.
    J Agric Food Chem; 2012 Jan 18; 60(2):665-75. PubMed ID: 22148415
    [Abstract] [Full Text] [Related]

  • 8. Non-thermal atmospheric pressure plasma induces apoptosis in oral cavity squamous cell carcinoma: Involvement of DNA-damage-triggering sub-G(1) arrest via the ATM/p53 pathway.
    Chang JW, Kang SU, Shin YS, Kim KI, Seo SJ, Yang SS, Lee JS, Moon E, Baek SJ, Lee K, Kim CH.
    Arch Biochem Biophys; 2014 Mar 01; 545():133-40. PubMed ID: 24486404
    [Abstract] [Full Text] [Related]

  • 9. Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells.
    Xiao D, Johnson CS, Trump DL, Singh SV.
    Mol Cancer Ther; 2004 May 01; 3(5):567-75. PubMed ID: 15141014
    [Abstract] [Full Text] [Related]

  • 10. Phenethyl isothiocyanate induces IPEC-J2 cells cytotoxicity and apoptosis via S-G2/M phase arrest and mitochondria-mediated Bax/Bcl-2 pathway.
    Liu S, Zhu Y, Yan S, Xiao H, Yi J, Li R, Wu J, Wen L.
    Comp Biochem Physiol C Toxicol Pharmacol; 2019 Dec 01; 226():108574. PubMed ID: 31446007
    [Abstract] [Full Text] [Related]

  • 11. Reactivation of mutant p53 by a dietary-related compound phenethyl isothiocyanate inhibits tumor growth.
    Aggarwal M, Saxena R, Sinclair E, Fu Y, Jacobs A, Dyba M, Wang X, Cruz I, Berry D, Kallakury B, Mueller SC, Agostino SD, Blandino G, Avantaggiati ML, Chung FL.
    Cell Death Differ; 2016 Oct 01; 23(10):1615-27. PubMed ID: 27258787
    [Abstract] [Full Text] [Related]

  • 12. Phenethyl isothiocyanate induced apoptosis via down regulation of Bcl-2/XIAP and triggering of the mitochondrial pathway in MCF-7 cells.
    Lee JW, Cho MK.
    Arch Pharm Res; 2008 Dec 01; 31(12):1604-12. PubMed ID: 19099231
    [Abstract] [Full Text] [Related]

  • 13. Anti-tumor effect of germacrone on human hepatoma cell lines through inducing G2/M cell cycle arrest and promoting apoptosis.
    Liu Y, Wang W, Fang B, Ma F, Zheng Q, Deng P, Zhao S, Chen M, Yang G, He G.
    Eur J Pharmacol; 2013 Jan 05; 698(1-3):95-102. PubMed ID: 23117090
    [Abstract] [Full Text] [Related]

  • 14. 2-Hydroxyethyl methacrylate-induced apoptosis through the ATM- and p53-dependent intrinsic mitochondrial pathway.
    Schweikl H, Petzel C, Bolay C, Hiller KA, Buchalla W, Krifka S.
    Biomaterials; 2014 Mar 05; 35(9):2890-904. PubMed ID: 24411679
    [Abstract] [Full Text] [Related]

  • 15. The dietary phytochemical 3,3'-diindolylmethane induces G2/M arrest and apoptosis in oral squamous cell carcinoma by modulating Akt-NF-κB, MAPK, and p53 signaling.
    Weng JR, Bai LY, Chiu CF, Wang YC, Tsai MH.
    Chem Biol Interact; 2012 Feb 05; 195(3):224-30. PubMed ID: 22290291
    [Abstract] [Full Text] [Related]

  • 16. Ovatodiolide isolated from Anisomeles indica induces cell cycle G2/M arrest and apoptosis via a ROS-dependent ATM/ATR signaling pathways.
    Yu CY, Jerry Teng CL, Hung PS, Cheng CC, Hsu SL, Hwang GY, Tzeng YM.
    Eur J Pharmacol; 2018 Jan 15; 819():16-29. PubMed ID: 28986085
    [Abstract] [Full Text] [Related]

  • 17. Epigenetic reactivation of RASSF1A by phenethyl isothiocyanate (PEITC) and promotion of apoptosis in LNCaP cells.
    Boyanapalli SS, Li W, Fuentes F, Guo Y, Ramirez CN, Gonzalez XP, Pung D, Kong AN.
    Pharmacol Res; 2016 Dec 15; 114():175-184. PubMed ID: 27818231
    [Abstract] [Full Text] [Related]

  • 18. Caspase-dependent apoptosis induction by phenethyl isothiocyanate, a cruciferous vegetable-derived cancer chemopreventive agent, is mediated by Bak and Bax.
    Xiao D, Zeng Y, Choi S, Lew KL, Nelson JB, Singh SV.
    Clin Cancer Res; 2005 Apr 01; 11(7):2670-9. PubMed ID: 15814648
    [Abstract] [Full Text] [Related]

  • 19. Phenethyl isothiocyanate-induced apoptosis in PC-3 human prostate cancer cells is mediated by reactive oxygen species-dependent disruption of the mitochondrial membrane potential.
    Xiao D, Lew KL, Zeng Y, Xiao H, Marynowski SW, Dhir R, Singh SV.
    Carcinogenesis; 2006 Nov 01; 27(11):2223-34. PubMed ID: 16774948
    [Abstract] [Full Text] [Related]

  • 20. p53 mutant-type in human prostate cancer cells determines the sensitivity to phenethyl isothiocyanate induced growth inhibition.
    Aggarwal M, Saxena R, Asif N, Sinclair E, Tan J, Cruz I, Berry D, Kallakury B, Pham Q, Wang TTY, Chung FL.
    J Exp Clin Cancer Res; 2019 Jul 15; 38(1):307. PubMed ID: 31307507
    [Abstract] [Full Text] [Related]

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